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Introduction About DYNAGLIPT D 5 TABLET
DYNAGLIPT D 5 TABLET is a combination of Dapagliflozin and Teneligliptin which belongs to a group of medicines called Antidiabetic agents. It is used in the management of type 2 diabetes mellitus. Along management with DYNAGLIPT D 5 TABLET follow regular exercise and diet plan as advised by the doctor to achieve better results.
Dapagliflozin increases urinary glucose excretion and reduces blood glucose levels. Teneligliptin works by increasing the release of insulin from the pancreas and decreasing the release of a hormone (glucagon) that raises blood sugar levels. This reduces fasting and post-meal sugar levels.
DYNAGLIPT D 5 TABLET is not recommended if you have type 1 diabetes mellitus, diabetic ketoacidosis, diabetic coma, severe infection, before and after surgery, serious trauma. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. DYNAGLIPT D 5 TABLET is not recommended for breastfeeding women as it may pass through breast milk. Safety and effectiveness of DYNAGLIPT D 5 TABLET in children and adolescents under 18 years of age have not been established.
Excessive consumption of alcohol intake may cause low blood sugar. The most common side effects of taking DYNAGLIPT D 5 TABLET are diarrhoea, nausea, vomiting, upset stomach, headache, low sugar levels, dizziness, constipation and fever. Contact your doctor if any of the above side effects worsen or persists for a longer duration.
Uses Of DYNAGLIPT D 5 TABLET
- It is used in the management of type 2 diabetes mellitus
How DYNAGLIPT D 5 TABLET Works
DYNAGLIPT D 5 TABLET is a combination of Dapagliflozin and Teneligliptin which helps to lower blood glucose levels. Dapagliflozin belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors which works by inhibiting the reabsorption of glucose in the kidneys, causing excess glucose to be excreted through urine. By lowering blood glucose levels, dapagliflozin helps to improve glycemic control in patients with type 2 diabetes. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor which works by inhibiting the enzyme DPP-4, which breaks down incretin hormones such as GLP-1 (glucagon-like peptide-1). By inhibiting DPP-4, teneligliptin increases the levels of GLP-1, which stimulates insulin secretion and reduces glucagon release. This helps to lower blood glucose levels.
How to use DYNAGLIPT D 5 TABLET
Take DYNAGLIPT D 5 TABLET as advised by your physician. Swallow DYNAGLIPT D 5 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking DYNAGLIPT D 5 TABLET without informing your doctor.
Side Effects Of DYNAGLIPT D 5 TABLET
Common
- diarrhoea
- nausea
- vomiting
- upset stomach
- headache
- low sugar levels
- dizziness
- constipation
- fever
- painful urination, repetitive urination
- urinary tract infections
- allergic reactions
Stop taking DYNAGLIPT D 5 TABLET and consult your doctor immediately, if you experience:
- serious urinary tract infections
- low blood sugar
- serious allergic reactions
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for diarrhea. Consult your doctor if the symptom did not improve.
Headache
Rest in a quiet, dark room. Apply hot or cold compresses to your head or neck.
Nausea And Vomiting
Stick to simple meals. Avoid eating oily, fried, and spicy foods. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom did not improve.
Stomach Discomfort
Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Consult your doctor if the symptom did not improve.
Warning & Precautions
Pregnancy
Monitoring requiredDYNAGLIPT D 5 TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Safe use of this medicine during pregnancy has not been established. Consult your doctor before taking the medicine.
Breastfeeding
ContraindicatedDYNAGLIPT D 5 TABLET is not recommended for breastfeeding women as it may pass through breast milk. Consult your doctor before taking DYNAGLIPT D 5 TABLET.
Alcohol
Consult your doctorExcessive consumption of alcohol intake may cause low blood sugar.
Kidney
Use with CautionDYNAGLIPT D 5 TABLET should be used with caution in patients with renal impairment. Consult your doctor before taking the medicine.
Liver
Use with CautionDYNAGLIPT D 5 TABLET should be used with caution in patients with severe hepatic impairment. No dose adjustment is recommended for patients with mild, moderate, or severe hepatic impairment. Consult your doctor before taking DYNAGLIPT D 5 TABLET.
Allergy
ContraindicatedDo not take DYNAGLIPT D 5 TABLET if you are allergic (hypersensitive) to Dapagliflozin or Teneligliptin or any other ingredients of this medicine.
Heart Disease
Use with CautionDYNAGLIPT D 5 TABLET should be used with caution in patients with congestive heart failure, arrhythmia, severe bradycardia, congenital prolonged QT syndrome or a history of Torsades de pointes. Consult your doctor before taking DYNAGLIPT D 5 TABLET.
Use In Pediatrics
Consult your doctorSafety and effectiveness of DYNAGLIPT D 5 TABLET in children and adolescents under 18 years of age have not been established.
Use In Geriatrics
Use with CautionDYNAGLIPT D 5 TABLET should be used with caution in elderly patients above 65 years of age. Consult your doctor before taking the medicine.
Others
DYNAGLIPT D 5 TABLET is not recommended for use, if you have:
- type 1 diabetes mellitus
- diabetic ketoacidosis
- diabetic coma
- severe infection, before and after surgery, serious trauma
Before taking DYNAGLIPT D 5 TABLET inform your doctor if you:
- have a history of urinary tract infections or problems with urination
- are on a low sodium (salt) diet
- are going to have surgery
- are eating less or there is a change in your diet
- are dehydrated.
- have or have had problems with your pancreas, including pancreatitis or surgery on your pancreas
Interactions
A. Drug-Drug interactions:
Before taking DYNAGLIPT D 5 TABLET inform to your doctor if you are taking any of these medicines:
- MAO inhibitors
- steroids
- medicines used for thyroid function
- medicines used for bacterial infection
Overdosage:
If you or anyone else take too much of DYNAGLIPT D 5 TABLET, contact your doctor immediately or go to a nearest hospital straight away.
Synopsis
| Drug | : | Dapagliflozin, Teneligliptin |
| Pharmacological Category | : | Sodium-glucose co-transporter 2 (SGLT2) inhibitors, Dipeptide peptidase-4 (DPP-4) inhibitor |
| Therapeutic Indication | : | Type 2 Diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
- Keep DYNAGLIPT D 5 TABLET out of reach of children
- Store at temperature below 25°C
FAQs About DYNAGLIPT D 5 TABLET
Q: What is DYNAGLIPT D 5 TABLET used for?
A: It is used in the management of type 2 diabetes mellitus. Along management with DYNAGLIPT D 5 TABLET follow regular exercise and diet plan as advised by the doctor to achieve better results.
Q: Can I stop taking DYNAGLIPT D 5 TABLET without consulting your doctor?
A: No. do not stop taking DYNAGLIPT D 5 TABLET without consulting your doctor because it may lead to unwanted side effects.
Q: Can I consume alcohol while taking DYNAGLIPT D 5 TABLET?
A: Excessive consumption of alcohol intake may cause low blood sugar. Consult your doctor for advice before taking the medicine.
Q: Will taking a higher dose of DYNAGLIPT D 5 TABLET be more effective?
A: No, taking a higher dose of DYNAGLIPT D 5 TABLET will not be effective. Always take the dose as advised by your physician.
Q: What precautions do I need to follow while taking DYNAGLIPT D 5 TABLET?
A: DYNAGLIPT D 5 TABLET is not recommended if you have type 1 diabetes mellitus, diabetic ketoacidosis, diabetic coma, severe infection, before and after surgery, serious trauma. It should be used with caution if you have a history of urinary tract infections or problems with urination, low sodium (salt) diet, are going to have surgery, dehydrated.
Q: What are the common side effects of DYNAGLIPT D 5 TABLET?
A: The most common side effects of taking DYNAGLIPT D 5 TABLET are diarrhoea, nausea, vomiting, upset stomach, headache, low sugar levels, dizziness, constipation and fever. Contact your doctor if any of the above side effects worsen or persists for a longer duration.
References
1. KD Tripathi MD. Hormones and related drugs. Essentials of medical pharmacology. Seventh edition. New Delhi, May 2013. Page – 274.
2. Ajay S. Dabhi, Nikita R. Bhatt, and Mohit J. Shah. Voglibose: An Alpha Glucosidase Inhibitor. December 2013, [Accessed on December 29th, 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919386/
3. AstraZeneca Pharmaceuticals. [Revised on September, 2023] [Accessed on December 30th, 2023] https://den8dhaj6zs0e.cloudfront.net/50fd68b9-106b-4550-b5d0-12b045f8b184/0be9cb1b-3b33-41c7-bfc2-04c9f718e442/0be9cb1b-3b33-41c7-bfc2-04c9f718e442_viewable_rendition__v.pdf
4. MICRO LABS LIMITED. [Revised on April, 2017] [Accessed on December 30th, 2023] https://rwandafda.gov.rw/wp-content/uploads/2022/11/TILYPTIN_20__TENELIGLIPTIN__TABLET-SMPC.pdf
5. John lee. [Accessed on December 30th, 2023] https://johnleeindia.com/product/tenalip-d-10-20/
6. Steris Pharma Pvt. Ltd. [Accessed on December 30th, 2023] https://www.sterisonline.com/blog/teneligliptin-amp-dapagliflozin
7. Leeford. [Accessed on December 30th, 2023] https://www.leeford.in/product/3460/dapaford-10-t
8. Steris Pharma Pvt. Ltd. [Accessed on December 30th, 2023] https://www.sterisindia.com/latest-update/dapagliflozin-tene/39189
Useful Diagnostic Tests
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Post Prandial Blood Sugar (PPBS)
- Insulin-Fasting
- Netmeds Diabetic Checkup
- Advance Diabetes Monitoring (Senior Female)
- Jaanch Diabetic Profile Basic




