Clobetamos Gel(Topical) 30gm
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Introduction About CLOBETAMOS GEL(TOPICAL)
CLOBETAMOS GEL(TOPICAL) is a combination of Clobetasol propionate and Lactic acid which belongs to a group of medicines called Topical Corticosteroids, and Alpha-hydroxy acids, respectively. CLOBETAMOS GEL(TOPICAL) is used to manage, control, prevent, and improve conditions and symptoms of corticosteroid-responsive dermatoses, moderate to severe plaque-type psoriasis, dry skin, scaly skin, and ichthyosis vulgaris.
Corticosteroid-responsive dermatoses are skin conditions that develop as a result of a reaction to corticosteroid medications and are characterised by symptoms such as dry skin, redness, itching, rashes, and/or sores. Psoriasis is a skin disease that causes a rash with itchy, scaly patches that most commonly occur on the knees, elbows, trunk, and scalp.
Ichthyosis vulgaris is an inherited or acquired skin condition that occurs when skin doesn’t shed its dead cells, leading to symptoms such as dry, itchy, rough skin that looks dirty, noticeably on the palms and soles of the feet.
CLOBETAMOS GEL(TOPICAL) should not be used in patients who have skin infections such as rosacea (severe flushing of the skin on and around the nose) or perioral dermatitis (spotty red rash around the mouth).Before applying CLOBETAMOS GEL(TOPICAL), inform your doctor if you have concomitant skin infections (skin diseases caused by parasites).
CLOBETAMOS GEL(TOPICAL) should only be used in pregnant or breastfeeding women if absolutely necessary.CLOBETAMOS GEL(TOPICAL) is not recommended for use in children (below 12 years) due to side effects such as HPA axis suppression (poor body defence against infection), Cushing’s syndrome (hormonal disorder), and intracranial hypertension (high blood pressure in the brain).
The most common symptoms of applying CLOBETAMOS GEL(TOPICAL) are burning and stinging sensations, irritation, itchy skin, red skin, and numbness of fingers. Consult your doctor if any of these symptoms get worse.
Uses Of CLOBETAMOS GEL(TOPICAL)
It is used to manage, control, prevent, & improve conditions, and symptoms of:
- corticosteroid -responsive dermatoses (skin condition that occurs as a reaction to corticosteroid medication)
- moderate to severe plaque-type psoriasis (itchy skin)
- dry skin
- scaly skin
- ichthyosis vulgaris (inherited skin disorder)
How CLOBETAMOS GEL(TOPICAL) Works
CLOBETAMOS GEL(TOPICAL) helps to manage skin infections. Clobetasol propionate manages inflammation by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy, and ammonium lactate acts as a moisturiser and provides relief from minor skin infections.
How to use CLOBETAMOS GEL(TOPICAL)
Always apply CLOBETAMOS GEL(TOPICAL), as directed by your physician. It is for external use only. On the affected area, apply a thin layer of this medicine. Managed areas on the face need not be covered with a plaster or bandage. Do not apply CLOBETAMOS GEL(TOPICAL) to your face beyond 5 days. Avoid applying CLOBETAMOS GEL(TOPICAL) around your eyes, including your eyelids.
Side Effects Of CLOBETAMOS GEL(TOPICAL)
Common
- burning and stinging sensation
- irritation
- itchy skin
- red skin
- folliculitis (inflammation of hair follicle)
- cracking and fissuring of the skin
- numbness of fingers
- skin atrophy (thin appearing skin)
- telangiectasia (small widen blood vessels on skin)
- dryness
- hypertrichosis (excessive hair growth)
- acneiform eruptions (a skin condition that causes small, raised, acne-like bumps on affected site)
- hypopigmentation(skin condition marked by lighter skin tone)
- perioral dermatitis (red rash that circles the mouth)
- allergic contact dermatitis (itchy rash)
- secondary infection
- stretch marks
- heat rash
- peeling skin
Uncommon
- eczema (skin inflammation)
- petechiae (a small red or purple spot caused by bleeding into the skin)
- hyperpigmentation (darkened patches or spots on the skin)
Rare
Stop applying CLOBETAMOS GEL(TOPICAL) and contact your doctor if you experience any of the following side effects:
- irritation
- signs of hypersensitivity reaction such as raised, itchy, red rash, mild redness and itching, severe blisters and swelling
How To Manage Side Effects
Dry Skin:
Try moisturising your skin with an ointment, cream, or lotion two or three times a day, or as often as needed. Moisturizers help to keep the area moist, so they work best on damp skin. After you bathe, pat your skin dry, then apply your moisturizer. Try to avoid using skin care products and soaps that contain alcohol, fragrances, dyes, or other chemicals.
Itchy Skin:
Avoid scratching your skin. Cool your skin by holding on to a damp towel. Try to have cool or warm baths. Wear loose clothing and do not wear tight clothes. Try to avoid using perfumed soaps, deodorants, or moisturizers, and always use unscented moisturizer.
Warning & Precautions
Pregnancy
CLOBETAMOS GEL(TOPICAL) should be used with caution during pregnancy only if its is clearly necessary. Consult your doctor before applying the medicine.
Breastfeeding
CLOBETAMOS GEL(TOPICAL) should be used with caution in breastfeeding women. Consult your doctor before applying the medicine.
Allergy
CLOBETAMOS GEL(TOPICAL) is not recommended for use if you are allergic to clobetasol propionate, ammonium lactate or any other ingredients of this medicine.
Others
CLOBETAMOS GEL(TOPICAL) is not recommended for use if you:
- have skin problems such as rosacea (severe flushing of skin on and around your nose), perioral dermatitis (spotty red rash around your mouth)
Before applying CLOBETAMOS GEL(TOPICAL), inform your doctor if you:
- have concomitant skin infections (skin disease caused by parasites)
Use in Pediatrics:
CLOBETAMOS GEL(TOPICAL) is not recommended for use in children (below 12 years) due to the high risk of occurrence of side effects such as HPA axis suppression (a condition of poor body defence against infection), Cushing’s syndrome (a hormonal disorder), and intracranial hypertension (high blood pressure in the brain). Consult your doctor before taking CLOBETAMOS GEL(TOPICAL).
Use in Geriatrics:
CLOBETAMOS GEL(TOPICAL) should be used with caution in elderly patients (aged 65 years or above). Consult your doctor before applying CLOBETAMOS GEL(TOPICAL).
Interactions
A. Drug-Drug Interactions:
Before applying CLOBETAMOS GEL(TOPICAL), inform your doctor, if you are applying any of the following medicine:
Overdosage:
If you or anyone else accidentally takes too much CLOBETAMOS GEL(TOPICAL), consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are HPA axis suppression (a condition that causes poor body defence against infection), Cushing's syndrome (a hormonal disorder), hyperglycemia (high blood sugar), and glucosuria (low sugar in urine).
Synopsis
| Drug | : | Clobetasol propionate, Ammonium lactate |
| Pharmacological Category | : | Topical Corticosteroid, Alpha-hydroxy acid |
| Therapeutic Indication | : | Corticosteroid -responsive dermatoses, moderate to severe plaque-type psoriasis, dry skin, scaly skin, ichthyosis vulgaris |
| Dosage Forms | : | Gel |
More Information
- Keep CLOBETAMOS GEL(TOPICAL) out of reach from children
- Store CLOBETAMOS GEL(TOPICAL) at room temperature
FAQs About CLOBETAMOS GEL(TOPICAL)
Q: What is the function of CLOBETAMOS GEL(TOPICAL)?
A: CLOBETAMOS GEL(TOPICAL) is used to manage, control, prevent, and improve conditions and symptoms of corticosteroid-responsive dermatoses (a skin condition that occurs as a reaction to corticosteroid medication), moderate to severe plaque-type psoriasis (itchy skin), dry and scaly skin, and ichthyosis vulgaris (an inherited skin disorder).
Q: What happens if too much CLOBETAMOS GEL(TOPICAL) is applied?
A: If you or anyone else applies too much or accidentally swallows CLOBETAMOS GEL(TOPICAL), consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are HPA axis suppression (a condition that causes poor body defence against infection), Cushing's syndrome (a hormonal disorder), hyperglycemia (high blood sugar), and glucosuria (low sugar in urine).
Q: Is CLOBETAMOS GEL(TOPICAL) safe to be used by children?
A: CLOBETAMOS GEL(TOPICAL) is not recommended for use in children (below 12 years) due to the high risk of occurrence of side effects such as HPA axis suppression (a condition of poor body defence against infection), Cushing’s syndrome (a hormonal disorder), and intracranial hypertension (high blood pressure in the brain). Consult your doctor before taking CLOBETAMOS GEL(TOPICAL).
Q: Who should avoid applying CLOBETAMOS GEL(TOPICAL)?
A: CLOBETAMOS GEL(TOPICAL) is not recommended for use in patients allergic to clobetasol propionate and ammonium lactate, which are also not recommended for use in patients suffering from skin problems such as rosacea (severe flushing of the skin on and around your nose) or perioral dermatitis (spotty red rash around your mouth). Consult your doctor before applying the medicine.
Q: Is CLOBETAMOS GEL(TOPICAL) safe to be used by pregnant and breastfeeding women?
A: CLOBETAMOS GEL(TOPICAL) should only be used or applied in pregnant or breastfeeding women if absolutely necessary. Consult your doctor before applying the medicine.
References
1. KD Tripathi. Drugs Acting on Skin and Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 895.
2. Andrew Herxheimer, Berthold Rzany, Hywel Williams, Luigi Naldi, Michael Bigby, Thomas Diepgen. Common inflammatory skin disease. Evidence-Based Dermatology. Second edition. 2008 Page – 134.
3. Clobetasol propionate. NIH National Library of Medicine. National Center for Biotechnology Information. PubChem [Revised in July 2022] [Accessed on 8th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Clobetasol-propionate#section=Biological-Half-Life
4. Clobetasol propionate gel. DailyMed. NIH U.S.National Library of Medicine. [Revised in October 2021] [Accessed on 14th June 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=f9df643a-015d-4101-ac8f-c1e05b052df5#:~:text=%2Dresponsive%20...-,Clobetasol%20Propionate%20Gel%2C%200.05%25%20is%20a%20super%2Dhigh%20potency,manifestations%20of%20corticosteroid%2Dresponsive%20dermatoses.
5. Ammonium lactate lotion. DailyMed. NIH U.S.National Library of Medicine. [Revised in October 2021] [Accessed on 14th June 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=dc3a6462-0f2c-4306-b5ef-c7b47395e959
6. Canbro Healthcare. Covate soft. [Accessed on 9th July 2022] https://www.canbro.in/product/clobetasol-propionate-0-05-ammonium-lactate-12
Useful Diagnostic Tests
- Patch test
- Blood test
- Skin biopsy
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