Zilokem 80mg Tablet 10'S

INTRODUCTION

ZILOKEM contain Azilsartan medoxomil which belongs to a group of medicine called angiotensin II receptor antagonists (AIIRAs). Angiotensin II is a substance occur naturally in body which tightens the blood vessels, thereby increasing your blood pressure. This medicine blocks this effect so that the blood vessels relax which helps lower your blood pressure.

It is used for treating high blood pressure (essential hypertension) in adult patients (over18 years of age). High blood pressure is a condition in which the force of the blood against the artery walls is high. The common side effects are dizziness, diarrhoea, increased blood creatine phosphokinase. It is not recommended for use in children and adolescents under 18 years. Before taking this medicine tell your doctor if you have ever had kidney, heart or liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF ZILOKEM

• Treat high blood pressure

HOW ZILOKEM WORKS

ZILOKEM works by relaxing the blood vessel by blocking the action of a chemical that usually makes blood vessels tighter. This lowers the blood pressure and allows the blood to flow more smoothly to different organs and the heart to pump more efficiently.

DIRECTIONS FOR USE

Always take ZILOKEM exactly as your doctor has told you. This medicine must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF ZILOKEM

HOW TO MANAGE SIDE EFFECTS

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.  

Diarrhoea:

Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without talk to a doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking,

• lithium (used to treat mental health problems)
• non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, diclofenac, or celecoxib (used to treat pain and inflammation)
• acetylsalicyclic acid (used to treat pain and inflammation)
• potassium supplements, potassium-sparing medicines or salt substitutes containing potassium (used for increasing the amount of potassium in your blood)
• heparin (used for thin blood)
• diuretics
• aliskiren or other medicine to lower your blood pressure (angiotensin converting enzyme inhibitor or angiotensin II receptor blocker such as enalapril, lisinopril, ramipril or valsartan, telmisartan, irbesartan

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ZILOKEM

What is high blood pressure?

High blood pressure is a condition in which the force of the blood against the artery walls is high.

Which class does ZILOKEM belong to?

This medicine belongs to a group of medicine called angiotensin II receptor antagonist (AIIRAs). Angiotensin II is a substance which occur naturally in the body. It tightens the blood vessels which in turn increases the blood pressure. It blocks this effect so that the blood vessels relax which helps lower your blood pressure.

How long it takes for ZILOKEM to show effect?

A reduction in your blood pressure will be measurable within 2 weeks of initiation of treatment and the full effect of your dose will be observed by 4 weeks.

REFERENCES

1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page – 358-359.

2. Caroline M Perry 1. Azilsartan medoxomil: a review of its use in hypertension. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. 1 Sep 2012. [Accessed 27 Nov 2020] https://pubmed.ncbi.nlm.nih.gov/22877322/

3. Emiliano Angeloni. Azilsartan medoxomil in the management of hypertension: an evidence-based review of its place in therapy. US National Library of Medicines, National Institutes of Health. 5 Apr 2016. [Accessed 27 Nov 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829189/

4. Takeda Ireland Limited, Jan 2020; Electronic Medicines Compendium (EMC); [Accessed 27 Nov 2020] https://www.medicines.org.uk/emc/files/pil.4074.pdf

USEFUL DIAGNOSTIC TESTS

• Kidney function test