ZEPTOL 200MG contains carbamazepine which belongs to the group of medicines called anti-convulsants. It is used to treat certain forms of epilepsy and trigeminal neuralgia (painful condition of face). It can also be used to control bipolar disorder if other medicines are not effective. Carbamazepine treats seizure and symptoms of trigeminal neuralgia by inhibiting voltage-dependent sodium channels and preventing action potentials. It is capable of decreasing mania symptoms in bipolar disorder by increasing dopamine turnover and increase GABA transmission.
Prior to the treatment, your doctor may want you to have a several blood tests to find your condition. Inform your doctor, if you have ever had problems with your bone marrow, porphyria or glaucoma before taking this medicine. The most common side effects of taking this medicine are nausea, vomiting, headache, blurred vision and fluid retention. Avoid drinking alcohol or grapefruit juice while taking this medicine, as it may increase your chance of experiencing side effects. ZEPTOL 200MG should be used with caution in pregnant, breastfeeding and in elderly patients.
Carbamazepine inhibits and prolongs the inactivation of voltage-dependent sodium channels at the synapse by lowering polysynaptic nerve response and inhibiting post-tetanic potentiation. Blockade of sodium channels, decreases the abnormal excitability of neurons and therefore controls seizures.
It acts as a specific analgesic for trigeminal neuralgia, by inhibiting lingual mandibular reflex and by reducing pain caused by stimulation of nerves in the face. It decreases mania symptoms in bipolar disorder by increasing dopamine turnover and GABA transmission.
Always take this medicine as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition.
Feeling sick or being sick:
Try taking this medicine with, or just after meal. Stick to simple meals.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
ZEPTOL 200MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.
ZEPTOL 200MG should be used with caution in breastfeeding women. Consult your doctor before taking this medicine.
Do not drive or operate any machines, because this medicine may make you feel dizzy or drowsy or may cause blurred vision.
Avoid consumption of alcohol while taking this medicine.
ZEPTOL 200MG should be taken with caution in patients with kidney disease. Consult your doctor for advice.
ZEPTOL 200MG should be taken with caution in patients with liver disease. Consult your doctor for advice.
Do not take this medicine if you are allergic to carbamazepine or any other similar ingredients like oxcarbazepine, amitriptyline or imipramine.
ZEPTOL 200MG should be taken with caution in patients with heart disease. Consult your doctor for advice.
Before taking this medicine, inform your doctor, if you have:
Talk to your doctor, if you are taking,
Drug | : | Carbamazepine |
Pharmacological Category | : | Anticonvulsant |
Therapeutic Indication | : | Epilepsy, Trigeminal neuralgia, Bipolar disorder |
Dosage Forms | : | Tablet, Syrup |
Store below 20-25°C and keep out of reach of children.
Can ZEPTOL 200MG cause Stevens-Johnson syndrome?
This medicine may rarely cause allergic reactions like Stevens-Johnson syndrome. Stop the treatment and consult your doctor immediately, if you experience it.
Can [GBNKEYORD] cause missed periods?
This medicine may cause menstrual irregularities. Consult your doctor for advice.
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5. Lundbeck LLC. A Study of the Pharmacokinetics (PK) and Safety of IV Carbamazepine Relative to Oral Carbamazepine in Adults with Epilepsy. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on April 2010] [Accessed 26th November 2020] https://clinicaltrials.gov/ct2/show/NCT01079351
6. Zahra Tolou-Ghamari, Mohammad Zare, Jafar Mehvari Habibabadi, and Mohammad Reza Najafi. A quick review of carbamazepine pharmacokinetics in epilepsy from 1953 to 2012. NCBI; PMC US National Library of Medicine, National Institute of Health. March 2013. [Accessed 26th November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743329/
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8. Novartis Pharmaceuticals Corporation. U.S. Food & Drug Administration. [Revised on February 2009] [Accessed 26th November 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/016608s101,018281s048lbl.pdf
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