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What is ZEMPRED?
- ZEMPRED contains methylprednisolone, which belongs to a group of medicines called corticosteroids
What ZEMPRED is used for?
Boosting your body with extra corticosteroid such as methylprednisolone can help following surgery (e.g. organ transplants), injuries or other stressful conditions.
These include inflammatory or allergic conditions affecting the:
- brain (e.g. tuberculous meningitis)
- bowel and gut (e.g. Crohn’s disease and ulcerative colitis)
- blood or blood vessels (e.g. leukaemia or arteritis, inflammation of the arteries)
- joints (e.g. rheumatic fever)
- lungs (e.g. asthma, tuberculosis)
- muscle (e.g. dermatomyositis and polymyositis)
- skin (e.g. pemphigus vulgaris, an auto-immune disorder in which the body’s immune system is overactive causing the skin to blister)
Talk to Doctor
Pregnancy & Breast Feeding
Children & Adolescents
Driving & Using Machines
Talk to your Doctor, if you:
- are allergic to ZEMPRED or any other ingredients of this medicine
- have any serious fungal infection to your lungs or oesophagus or any other infection which is not being treated with an antibiotic or antiviral medicine
- have recently had or are about to have any vaccination
- get a rash or another symptom of an infection
- have chickenpox, measles or shingles
- have worm infestation (e.g. threadworm)
- have severe depression or manic depression (bipolar disorder
- have diabetes (or if there is a family history of diabetes)
- have fits or seizures
- have glaucoma (increased pressure in the eye) or if there is a family history of glaucoma, or if you have cataracts
- have viral (e.g. herpes) or fungal eye infection
- are recently suffered a heart attack
- have heart problems, including heart failure, hypertension
- have hypothyroidism (an under-active thyroid)
- have pancreatitis (inflammation of the pancreas which causes severe pain in the abdomen and back)
- have peritonitis (inflammation of the thin lining (peritoneum) around the gut and stomach)
- have kidney or liver disease
- Cataracts have been observed in infants born to mothers treated with long-term ZEMPRED during pregnancy
- There is a risk of low birth weight of a baby; this risk can be minimised by taking the lowest effective dose of the ZEMPRED
- Small amounts of ZEMPRED may get into breast milk
- If you are pregnant, think you may be pregnant or planning to have a baby or are breastfeeding, ask your doctor for advice before taking this medicine, as it could slow the baby’s growth
- ZEMPRED can affect growth in children, so your doctor will prescribe the lowest dose that will be effective for your child
- Undesirable effects, such as dizziness, vertigo, visual disturbances and fatigue are possible after treatment with ZEMPRED If you are affected do not drive or operate machinery
Tell your doctor if you are taking:
- acetazolamide - used to treat glaucoma and epilepsy
- aminoglutethimide or cyclophosphamide – used for treating cancer
- anticoagulants - used to ‘thin’ the blood such as acenocoumarol, phenindione and warfarin
- anticholinesterases - used to treat myasthenia gravis (a muscle condition) such as distigmine and neostigmine
- antibacterials (such as isoniazid, erythromycin, clarithromycin and troleandomycin)
- antidiabetics – medicines used to treat high blood sugar
- aprepitant or fosaprepitant – used to prevent nausea and vomiting
- aspirin and non-steroidal anti-inflammatory medicines (also called NSAIDs) such as ibuprofen used to treat mild to moderate pain
- barbiturates, carbamezipine, phenytoin and primidone – used to treat epilepsy
- carbenoxolone and cimetidine - used for heartburn and acid indigestion
- ciclosporin - used to treat conditions such as severe rheumatoid arthritis, severe psoriasis,organ or bone marrow transplant
- digoxin - used for heart failure and/or an irregular heartbeat
- diltiazem or mibefradil – used for heart problems or high blood pressure
- ethinylestridiol and norethisterone – an oral contraceptive
- antivirals (such as ritonavir, indinavir) and pharmacokinetic enhancers (such as cobicistat) used to treat HIV infections
- ketoconazole or itraconazole – used to treat fungal infections
- pancuronium or vecuronium – or other medicines called neuromuscular blocking agents which are used in some surgical procedures
- potassium depleting agents – such as diuretics (sometimes called water tablets), amphotericin B, xanthenes or beta2 agonists (e.g. medicines used to treat asthma)
- rifampicin and rifabutin – antibiotics used to treat tuberculosis (TB)
- tacrolimus – used following an organ transplant to prevent rejection of the organ
- vaccines - You must not have ‘live’ vaccines while using this medicine. Other vaccines may be less effective
- Always take this medicine exactly as your doctor has told you
For Adults
- The normal daily dose is between 4 mg and 360 mg per day, depending on your condition and how severe it is. Your doctor will prescribe the lowest dose possible
- Swallow the tablets whole with a drink of water. The score line is not intended for breaking the tablet
If you take more ZEMPRED
- If you take too many ZEMPRED or if someone else has taken your medicine, talk to your doctor immediately and you may need Medical attention
If you forget to take ZEMPRED
- If you have forgotten to take your ZEMPRED take them as soon as possible on the same day. Do not take a double dose
If you stop taking ZEMPRED
- Do not stop taking the ZEMPRED until the doctor has told you to do so
Like all medicines, this medicine can cause side effects although not everybody gets them.
- stomach pain, bleeding from the back passage, black or bloodstained stools, vomiting blood
- high blood pressure, symptoms of which are headaches, or generally feeling unwell
- swelling and high blood pressure, caused by increased levels of water and salt content
- cramps and spasms, due to the loss of potassium from your body. in rare cases this can lead to congestive heart failure
- damage to the optic nerve or cataracts (indicated by failing eyesight)
- slowing of normal growth in infants, children and adolescents which may be permanent
- round or moon-shaped face (Cushingoid facies)
- muscle weakness or wasting
- feeling depressed, including thinking about suicide
- feeling high (mania) or moods that go up and down
- feeling anxious, having problems sleeping, difficulty in thinking or being confused and losing your memory
- feeling, seeing or hearing things which do not exist. having strange and frightening thoughts, changing how you act or having feelings of being alone
- acne, poor wound healing, thinning of skin
- Protect from excess heat and light
- Keep this medicine out of reach of children
- Store at room temperature below (15-25°C)
- Do not use this medicine after the expiry date
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DISCLAIMER
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
