INTRODUCTION

Z STAT 5MG contain rosuvastatin which belongs to a group of medicine called statins. It is used to treat high cholesterol level and helps to prevent heart attack and stroke. Cholesterol is a fatty substance normally found in bloodstream. When it gets builds up in your blood vessels it may lead to narrowing of blood vessel resulting in heart attack or stroke.

Heart attack occur when an artery supplying your heart with blood and oxygen become blocked. Stroke occur when the blood supply to part of your brain is interrupted and prevent brain tissue from getting oxygen and nutrient. Low cholesterol levels can reduce the risk of having a heart attack, a stroke or related health problems. Z STAT 5MG treat high cholesterol level and helps to prevent heart attack and stroke.

Always take Z STAT 5MG exactly as your doctor has told you. This medicine must be taken with or without food. It should be swallowed whole with water. Do not crush or chew the medicine. This medicine is not recommended for use in children and adolescents below 18 years of age. Before taking this medicine talk to your doctor if you have any kidney, liver, heart problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine. Diabetic patients should monitor their blood sugar level while taking this medicine. The most common side effects include headache, muscle pain, dizziness, weakness, stomach pain, and constipation.

USES OF Z STAT 5MG

• Treat high cholesterol level
• Helps to prevent heart attack and stroke

HOW Z STAT 5MG WORKS

It works by blocking an enzyme (HMG-CoA-reductase) that is required by the body to make cholesterol, thereby lowering "bad" cholesterol (LDL) and triglycerides, and raising "good" cholesterol (HDL).

DIRECTIONS FOR USE

Always take Z STAT 5MG exactly as your doctor has told you. This medicine must be taken with or without food. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF Z STAT 5MG

HOW TO MANAGE SIDE EFFECTS

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Stomach pain:

Keep try to rest and relax. Eat and drink slowly and smaller and frequent meals. Applying a heat pad or covered hot water bottle on your stomach may also help. If still pain persists, speak to your doctor.

Constipation: 

Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Nausea:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Dizziness:

Lie down and close our eyes. Drink plenty of water and keep hydrated. Take plenty of sleep.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking,

• Ciclosporin (used for after organ transplants)
• Regorafenib, darolutamide (used to treat cancer)
• Warfarin or clopidogrel (used for thinning the blood)
• Fibrates such as gemfibrozil, fenofibrate or any other medicine such as ezetimibe (used to treat lower cholesterol)
• Antacids (used to neutralise acid in your stomach)
• Antibiotic such as erythromycin, fusidic acid (used to treat infection)
• Oral contraceptive (the pill)
• Hormone replacement therapy
• Any antiviral medicines

SYNOPSIS

MORE INFORMATION

Store below 30°C and keep out of reach of children.

FAQs ABOUT Z STAT 5MG

Can I take Z STAT 5MG during breastfeeding?

It is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

What foods should be avoided when taking Z STAT 5MG?

You should avoid grapefruit juice while taking this medicine.

How do you take Z STAT 5MG?

This medicine should be taken once a day. It can be taken with or without food. It should be swallowed whole with water. Do not crush or chew the medicine. Try taking this medicine at the same time every day.

REFERENCES

1. KD Tripathi. Hypolipidaemic Drugs and Plasma Expanders. Essentials of Medical Pharmacology. Seventh edition,2013. Page-637.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page-3464-3466.

3. T Teramoto 1, C Watkins. Review of efficacy of rosuvastatin. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. January 2005. [Accessed 27 Oct 2020] https://pubmed.ncbi.nlm.nih.gov/15707472/

4. Zentiva k.s.; Electronic Medicines Compendium (EMC); [Revised on Oct 2018] [Accessed 27 Oct 2020] https://www.medicines.org.uk/emc/files/pil.8866.pdf

5. APL Swift Services (Malta) Limited; Electronic Medicines Compendium (EMC); [Revised on Mar 2019] [Accessed 27 Oct 2020] https://www.medicines.org.uk/emc/files/pil.4367.pdf

6. AstraZeneca UK Ltd ; Electronic Medicines Compendium (EMC); [Revised on Aug 2020] [Accessed 27 Oct 2020] https://www.medicines.org.uk/emc/files/pil.6779.pdf

7. APL Swift Services (Malta) Limited; Electronic Medicines Compendium (EMC); [Revised on Mar 2019] [Accessed 27 Oct 2020]  https://www.medicines.org.uk/emc/files/pil.4365.pdf

8. Wilmington, AstraZeneca Pharmaceuticals LP 2003; U.S. Food & Drug Administration; [Revised on 2010] [Accessed 27 Oct 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021366s016lbl.pdf

USEFUL DIAGNOSTIC TESTS

• Cholesterol - HDL
• Cholesterol - LDL
• Cholesterol - Total