Z SAR H 50MG is a combination of Hydrochlorothiazide and Losartan which belongs to the group of medicines called Thiazide like diuretics and Angiotensin II receptor antagonists respectively. Z SAR H 50MG is indicated for the treatment of essential hypertension. Essential hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels of several organs, thus causing heart attack, heart or kidney failure, stroke, or even blindness.
Losartan is an Angiotensin-receptor blocker which effectively reduces blood pressure by blocking the actions of Angiotensin – II (a substance that causes narrowing of blood vessels and increase in blood pressure) and hydrochlorothiazide is a diuretic which acts by increasing urine output, thus leading to a decrease in blood pressure. During treatment with Z SAR H 50MG your doctor might regularly monitor your blood pressure, kidney function and electrolyte levels at regular intervals to avoid any untoward side effects.
Z SAR H 50MG is not suitable for use in children (aged less than 18 years) and in adult patients with severe kidney or liver impairment. Long-term use of Z SAR H 50MG may increase the risk of some types of skin and lip cancer, and therefore always protect your skin from sun rays and UV exposure. Z SAR H 50MG is not recommended for use in breast-feeding women and pregnant women (especially after 3 months of gestation), as it may cause potential harm to the unborn baby. The most common side effects of Z SAR H 50MG are cough, diarrhea, stomach pain, dizziness, tiredness, and headache. Consult your doctor if any of the symptom bothers you.
Z SAR H 50MG reduces elevated blood pressure, where hydrochlorothiazide works by making the kidneys pass more water and salt (i.e., urine) and losartan works by inhibiting the binding of angiotensin II (a substance produced in the kidneys which causes narrowing of blood vessels) to its receptors, thus causing the blood vessels to relax which in turn decreases elevated blood pressure.
Take Z SAR H 50MG as advised by your physician. Swallow Z SAR H 50MG with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Stop taking Z SAR H 50MG and contact your doctor immediately if you experience the following side effects:
Nausea:
Take Z SAR H 50MG with or just after meals. Stick to simple meals and avoid eating rich or spicy food. If the symptom did not improve, consult your doctor.
Indigestion:
Eat smaller and frequent meals. Try to eat and drink slowly and follow a regular physical activity. If the symptom did not improve, consult your doctor.
Diarrhea:
Drink lots of fluids, such as water, fruit juice or electrolytes to keep yourself hydrated. Avoid taking medicine on your own to treat diarrhea. Consult your doctor if the symptom did not improve on its own.
Stomach pain:
Try to rest and relax. Try to eat and drink slowly or have smaller and frequent meals. Keep a heat pad on your stomach and avoid eating rich or spicy food. If the symptom did not improve, consult your doctor.
Headache:
Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.
Z SAR H 50MG is not recommended for use in pregnant women and should not be used if you are more than 3 months pregnant, as it may cause serious harm to your baby. Consult your doctor before taking Z SAR H 50MG.
Z SAR H 50MG is not recommended for use in breast-feeding mothers. Your doctor may choose another treatment if you wish to breast-feed. Consult your doctor before taking Z SAR H 50MG.
Do not drive or operate any machines if your ability is affected after taking Z SAR H 50MG.
Avoid consumption of alcohol while taking Z SAR H 50MG because it may aggravate your existing condition and increases the effect of Z SAR H 50MG.
Z SAR H 50MG is not recommended for use in patients with severe kidney impairment or kidneys not producing any urine. It should be used with caution in patients having renal artery stenosis (narrowing of renal arteries) or functioning of one kidney or have had a recent kidney transplant. Consult your doctor before taking Z SAR H 50MG.
Z SAR H 50MG is not recommended for use in patients with severe liver impairment. It should be used with caution in patients having history of mild to moderate liver impairment. Consult your doctor before taking Z SAR H 50MG.
Do not take Z SAR H 50MG if you are allergic to Hydrochlorothiazide or Losartan or other sulfonamide-derived substances (Ex. other thiazides and some antibacterial drugs such as co-trimoxazole).
Z SAR H 50MG should be used with caution in patients with asthma and in patients those who experienced breathing or lung problems following hydrochlorothiazide intake in the past. Consult your doctor before taking Z SAR H 50MG.
Z SAR H 50MG should be used with caution if you have heart problems (such as heart failure, atherosclerosis (narrowing of the arteries), angina pectoris, aortic or mitral valve stenosis (narrowing of valves of the heart) or hypertrophic cardiomyopathy (thickening of heart muscle)). Consult your doctor before taking Z SAR H 50MG.
Z SAR H 50MG is not recommended for use if you have:
Before taking Z SAR H 50MG, inform your physician if you:
Use in pediatrics:
Z SAR H 50MG is not recommended for use in children. Consult your doctor for advice.
Use in geriatrics:
Z SAR H 50MG should be taken with caution in elderly patients (aged 65 years or above). Consult your doctor before taking Z SAR H 50MG.
A. Drug-Drug interactions:
Before taking Z SAR H 50MG inform to your doctor, if you are taking any of these medicines:
B. Drug-Food interaction:
While taking Z SAR H 50MG avoid excessive consumption of dietary salt as it may counteract the effect of this medicine.
Overdosage:
If you or anyone else take too much of Z SAR H 50MG, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of Z SAR H 50MG include drop in blood pressure, palpitations, slow pulse, changes in blood composition and dehydration.
Drug | : | Hydrochlorothiazide, Losartan |
Pharmacological Category | : | Diuretics, Angiotensin II receptor antagonists |
Therapeutic Indication | : | Hypertension |
Dosage Forms | : | Tablet |
What is Z SAR H 50MG used for?
Z SAR H 50MG is indicated for the treatment of essential hypertension. Essential hypertension (also known as high blood pressure) is a medical condition in which the force of the blood exerted against the walls of the artery remains very high, and as a result it may lead to severe damage to the blood vessels of several organs, thus causing heart attack, heart or kidney failure, stroke, or even blindness.
Can Z SAR H 50MG cause dizziness?
Yes. Z SAR H 50MG may cause dizziness in you. Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy as precaution. Consult with your doctor for advice before taking Z SAR H 50MG.
Can Z SAR H 50MG be taken during breastfeeding?
Z SAR H 50MG is not recommended for use in breast-feeding mothers. Your doctor may choose another treatment if you wish to breast-feed. Consult your doctor before taking Z SAR H 50MG.
Can Z SAR H 50MG be used in patients with liver disease?
Z SAR H 50MG is not recommended for use in patients with severe liver impairment. It should be used with caution in patients having history of mild to moderate liver impairment. Your doctor may adjust the dose depending upon liver function. Consult your doctor before taking Z SAR H 50MG.
Does Z SAR H 50MG increases urination?
Yes, Z SAR H 50MG contains hydrochlorothiazide a diuretic agent which works by removing excess fluid from the body through kidneys which leads to increased passage of urination. Excess water loss in body may result in dehydration. During treatment with Z SAR H 50MG if you are always feeling tired, thirsty, or you have muscle cramps constantly, immediately consult your doctor for advice.
What to do If I forget to take Z SAR H 50MG?
You should take Z SAR H 50MG immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose of Z SAR H 50MG to match up your missed dose.
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