Availability & Expiry
INTRODUCTION
XOXE 125MG DRY SYRUP contains Cefuroxime which belongs to the group of medicines called Antibiotics. It is used to treat bacterial infections such as pharyngitis and tonsillitis (upper respiratory tract infection), acute bacterial otitis media (infection of the middle ear), cystitis (infection of the urinary bladder), pyelonephritis (infection affecting the kidneys), acute bacterial maxillary sinusitis (infection of the nasal cavity and sinuses), and impetigo (infection of the skin).
Before starting the treatment, your doctor may want to do some tests to know the type of bacteria causing the infection and monitor bacterial sensitivity to XOXE 125MG DRY SYRUP during the treatment. Before giving XOXE 125MG DRY SYRUP to your child, inform your doctor if your child is allergic (hypersensitive) to cefuroxime, any other group of cephalosporins and penicillin antibiotics.
Before giving XOXE 125MG DRY SYRUP to your child, inform your doctor if your child have or had any heart problems, liver or kidney problems. During the therapy, your doctor would regularly monitor your child’s health to avoid the risk of side effects.
Your doctor will prescribe the right dose and duration depends on the child’s age, body weight and health condition, so stick to the dose, time, and duration prescribed by the doctor. Minor and temporary side effects may be experienced after the intake of this medicine. These includes dizziness, diarrhoea and sickness.
Generally, these effects subside once the child’s body adapts to the medicine. However, in case of prolonged or bothersome events, consult your doctor immediately without any delay. Inform your doctor about your child’s complete medical history including any previous episodes of allergies.
USES OF XOXE 125MG DRY SYRUP
It is used to treat:
- respiratory tract infections
- ear nose and throat infections
- skin and skin structure infections
- urinary tract infections
- intra-abdominal infections
HOW XOXE 125MG DRY SYRUP WORKS
XOXE 125MG DRY SYRUP is a second-generation cephalosporin that interferes with the production of the bacterial cell wall by blocking its binding to specific binding proteins located inside the bacterial cell wall. This leads to breaking down the cell wall of the bacteria and reducing its stability, thus causing cell damage, and eventually causing bacterial elimination.
DIRECTIONS FOR USE
Take XOXE 125MG DRY SYRUP as advised by your physician. Shake well before use. It is for pediatric use only. Your doctor will prescribe the right dose depends on your child’s age body weight and disease condition.
SIDE EFFECTS OF XOXE 125MG DRY SYRUP
COMMON
- headache
- dizziness
- gastrointestinal disturbances
- transient rise in liver enzymes
- diarrhoea
- feeling sick
- stomach pain
RARE
Stop giving XOXE 125MG DRY SYRUP and contact your doctor immediately if your child experience any of the following side effects:
- severe allergic reactions such as raised and itchy rash, rash with blisters swelling on the face and mouth causing difficulty in breathing
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Give lots of fluids, such as water or fruit juices to keep your child hydrated. Avoid giving any medicine on your own for treating diarrhoea. Consult your doctor if the symptom did not improve.
Stomach Pain
Give your child smaller and frequent meals. Keep a heating pad on the stomach. If the symptom does not improve, contact your doctor.
Headache
Give plenty of water and apply a wet or cold cloth on child’s forehead. Apply pain balm to head to ease off the pain. If there is no improvement in the symptom, contact your doctor.
WARNING & PRECAUTIONS
DRIVING AND USING MACHINES
Use with CautionDo not allow your child drive or play outdoors, as XOXE 125MG DRY SYRUP may cause dizziness or blurry vision. Consult your doctor before giving XOXE 125MG DRY SYRUP.
KIDNEY
Use with CautionXOXE 125MG DRY SYRUP should be used with caution if the child have kidney disease. Consult your doctor before giving XOXE 125MG DRY SYRUP.
LIVER
Use with CautionXOXE 125MG DRY SYRUP should be used with caution if the child have liver disease. Consult your doctor before giving XOXE 125MG DRY SYRUP.
ALLERGY
ContraindicatedDo not give XOXE 125MG DRY SYRUP if your child is allergic (hypersensitive) to Cefuroxime or other cephalosporins and antibiotics such as penicillins, monobactams and carbapenems.
LUNGS
Use with CautionXOXE 125MG DRY SYRUP should be used with caution if the child have any lung problems. Consult your doctor before giving XOXE 125MG DRY SYRUP.
HEART DISEASE
Use with CautionXOXE 125MG DRY SYRUP should be used with caution if your child have any heart disease. If needed, dose will be adjusted accordingly. Consult your doctor for advice.
USE IN PEDIATRICS
Consult your doctorXOXE 125MG DRY SYRUP is not recommended in children below 3 months of age as the safety and effectiveness are not known in this age group. Your doctor will give the right dose depends on your child’s age, body weight and disease condition.
INTERACTIONS
A. Drug-Drug interactions:
Before using XOXE 125MG DRY SYRUP, inform your doctor if your child is taking any medicines including prescription, non-prescription and herbal supplements.
Overdosage:
If your child accidentally takes too much of XOXE 125MG DRY SYRUP, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Cefuroxime |
| Pharmacological Category | : | Cephalosporin Antibiotics |
| Therapeutic Indication | : | Treats Bacterial infections |
| Dosage Forms | : | Tablet, Injection, Capsule, Syrup, Dry Suspension, Drops, Dispersible tablet |
MORE INFORMATION
- Keep out of reach of children
- Store at room temperature
FAQs ABOUT XOXE 125MG DRY SYRUP
Q: Is XOXE 125MG DRY SYRUP the same as penicillin?
A: No, XOXE 125MG DRY SYRUP belongs to the second-generation class of cephalosporins and is active against numerous gram-positive and gram-negative bacteria, including those who show resistance to other antibiotics such as penicillin.
Q: What if my child takes too much XOXE 125MG DRY SYRUP?
A: XOXE 125MG DRY SYRUP is unlikely to cause harm if you give an extra dose by mistake. However, you must still tell your child’s doctor immediately.
Q: Can other medicines be given at the same time as XOXE 125MG DRY SYRUP?
A: XOXE 125MG DRY SYRUP may interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting XOXE 125MG DRY SYRUP. Also, check with your child’s doctor before giving any medicine to your child.
Q: For how long should I give XOXE 125MG DRY SYRUP?
A: Your doctor might advise you on how long your child should continue to take XOXE 125MG DRY SYRUP. You will need to consult your doctor from time to time to review the child’s treatment and assess the symptoms.
Q: Can XOXE 125MG DRY SYRUP be taken in new born babies?
A: No, XOXE 125MG DRY SYRUP is not recommended for children younger than 3 months of age. Consult your doctor for advice before giving the medicine.
REFERENCES
1. KD Tripathi. Second-generation cephalosporins. Essentials of Medical Pharmacology. Eighth edition. Page - 777.
2. Scott LJ, Ormrod D, Goa KL. Cefuroxime axetil: an updated review of its use in the management of bacterial infections. Drugs. 2001.National Library of Medicine. Pubmed.gov. [Accessed on 10th September 2022] https://pubmed.ncbi.nlm.nih.gov/11558834/
3. GlaxoSmithKline. [Revised in January 2007] [Accessed on 10th September 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/050605s042lbl.pdf
4. Glaxo Wellcome UK Limited. Electronic Medicines Compendium (emc) [Revised in November 2019] [Accessed on 10th September 2022] https://www.medicines.org.uk/emc/files/pil.3814.pdf
5. Chiros Pharma. [Revised in February 2019] [Accessed on 10th September 2022] https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/GORBACEF%20125%20(Cefuroxime%20Powder%20for%20Oral%20Suspension).pdf
6. Unichem Industries Ltd. [Revised in October 2019] [Accessed on 10th September 2022] https://fdaghana.gov.gh/img/pils/Kefrox%20125mg_5ml%20Oral%20Suspension%20(Cefuroxime%20Axetil%20Oral%20Suspension).pdf
7. GlaxoSmithKline (Ireland) Ltd. Electronic Machine Compendium [Revised in January 2018] [Accessed on 10th September 2022] https://gskpro.com/content/dam/global/hcpportal/en_MT/PDF/Homepage/Products/zinnat/Zinnat%20125mg.pdf
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
PRODUCT DETAILS
ALTERNATE BRANDS
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