Vymada 50mg Tablet 14'S

Heart Failure Rx required

Best Price* ₹ 942.00 MRP ₹ 1,177.50
(Inclusive of all taxes) *14 Tablet(s) in a Strip * Mkt: Novartis Healthcare Pvt Ltd * Country of Origin: Switzerland * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

VYMADA 50MG is a combination of Sacubitril and Valsartan which belongs to a group of medicines called Angiotensin receptor neprilysin inhibitors. VYMADA 50MG is indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (New York Heart Association Class II-IV) and reduced ejection fraction. Heart failure occurs when the heart is weak and cannot pump enough blood to the lungs and to the rest of the body and it is characterized by symptoms such as breathlessness, fatigue, tiredness, and ankle swelling.

Sacubitril is a neprilysin inhibitors which works by relaxing and widening the blood vessels and makes it easier for the heart to pump blood throughout the body. Valsartan is an angiotensin-II receptor blocker works by relaxing the blood vessels by blocking a substance called angiotensin-II (causing blood vessels to tighten) which is produced in the body and thus lowers the blood pressure.

Before taking VYMADA 50MG inform your doctor if you have liver, kidney, or heart problems. VYMADA 50MG is not recommended for use in pregnant and breast-feeding women. It is not suitable for use in children and adolescents under 18 years of age and it should be used with caution in elderly patients (65 years of age and above). Before taking VYMADA 50MG inform your doctor about previous allergy and medication history to prevent serious effect. The most common side effects of taking VYMADA 50MG are dizziness, cough headache, tiredness, nausea, and weakness. Contact your doctor if any of the symptoms worsen.

USES OF VYMADA 50MG

  • Treats long-term heart failure in adults

HOW VYMADA 50MG WORKS

VYMADA 50MG helps to treat long-term heart failure, where sacubitril works by relaxing and widening the blood vessels and makes it easier for the heart to pump blood throughout the body and valsartan works by relaxing the blood vessels by blocking a substance called angiotensin-II (causing blood vessels to tighten) which is produced in the body and thus lowers the blood pressure.

DIRECTIONS FOR USE

Take VYMADA 50MG as advised by your physician. Swallow VYMADA 50MG with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF VYMADA 50MG

COMMON

  • dizziness, light-headedness (low blood pressure)
  • signs of high levels of potassium in the blood (irregular heartbeat, muscle weakness)
  • decrease in renal function
  • cough
  • diarrhoea
  • signs of low red blood cells (anemia)
  • tiredness
  • headache
  • fainting or spinning sensation
  • weakness
  • nausea
  • inflammation of lining of the stomach (stomach pain, nausea)
  • signs of low sugar levels in the blood (fast heartbeat, sweating, nervousness, or anxiety)

UNCOMMON

  • allergic reaction with rash and itching
  • dizziness when switching from sitting to standing position

RARE

  • hallucinations
  • changes in sleeping pattern

Stop taking VYMADA 50MG and contact your doctor immediately if you experience any of the following side effects:

  • severe allergic reactions (swelling of the face, lips, tongue, or throat, which may cause difficulties in breathing or swallowing (angioedema))

HOW TO MANAGE SIDE EFFECTS

Tiredness:

Drink plenty of fluids and eat balanced diet and frequent meals. Do regular minimal exercise and follow regular sleep schedule. Consult your doctor if your symptom did not improve.

Nausea:

Stick to simple meals. Avoid eating oily, fried, and spicy foods. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom did not improve.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.

WARNING & PRECAUTIONS

PREGNANCY

VYMADA 50MG is not recommended for use in early pregnancy and must not be used in pregnant women when more than 3 months pregnant, as it may cause serious harm to the baby. Consult your doctor before taking VYMADA 50MG if you think you may be pregnant.

BREASTFEEDING

VYMADA 50MG is not recommended for use in breastfeeding women. Consult your doctor before taking VYMADA 50MG if you are breast-feeding or about to start breast-feeding.

DRIVING AND USING MACHINES

Avoid driving or handle any machines while taking VYMADA 50MG because it may cause dizziness or tiredness.

KIDNEY

VYMADA 50MG should be used with caution in patients with severe kidney disease and with narrowed kidney artery. Consult your doctor before taking VYMADA 50MG.

LIVER

VYMADA 50MG is not recommended in patients with severe liver disease and it should be used with caution in patients with liver disease. Consult your doctor before taking VYMADA 50MG.

ALLERGY

Do not take VYMADA 50MG if you are allergic (hypersensitive) to Sacubitril and Valsartan.

OTHERS

VYMADA 50MG is not recommended for use, if you have:

  • diabetes or impaired kidney function (and being treated with aliskiren (blood pressure lowering medicine))
  • personal or family history of angioedema (when taking angiotensin receptor blockers (ARB) such as valsartan, telmisartan)

Before taking VYMADA 50MG inform your doctor if you have:

  • history of angioedema
  • low blood pressure
  • vomiting or diarrhea
  • dehydration
  • hallucinations, paranoia, or changes in sleeping pattern

Use in pediatrics:

VYMADA 50MG is generally not recommended for use in children and adolescents (under 18 years of age). Consult child’s doctor for advice.

Use in geriatrics:

VYMADA 50MG should be used with caution in elderly patients (above 65 years of age). Consult your doctor before taking VYMADA 50MG.

INTERACTIONS

A. Drug-Drug interactions:

Before taking VYMADA 50MG inform to your doctor, if you are taking any of these medicines: 

  • enalapril, lisinopril or ramipril (treats high blood pressure)
  • aliskiren and angiotensin receptor blockers such as telmisartan, losartan (treats heart failure)
  • atorvastatin (lowers high cholesterol levels)
  • sildenafil (treats erectile dysfunction or lung hypertension)
  • potassium supplements, salt substitutes containing potassium, potassium-sparing medicines such as spironolactone (used to increase potassium levels in blood)
  • heparin, warfarin (treats blood clot)
  • non-steroidal anti-inflammatory medicines (NSAIDs) such as ibuprofen, indomethacin, or selective cyclooxygenase-2 (Cox-2) inhibitors such as celecoxib (treats pain and inflammation)
  • lithium (used to treat psychiatric illness)
  • furosemide (used to increase the amount of urine)
  • nitroglycerine (treats angina pectoris)
  • rifamycin (treats infections)
  • ciclosporin (used to prevent rejection of transplanted organs)
  • ritonavir (used to treat HIV/AIDS)
  • metformin (treats diabetes)

Overdosage:

If you or anyone else take too much of VYMADA 50MG, contact your doctor immediately or go to a nearest hospital straight away. Overdosage symptoms of VYMADA 50MG includes severe dizziness and fainting.

SYNOPSIS

Drug :   Sacubitril and Valsartan
Pharmacological Category :   Neprilysin Inhibitor, Angiotensin II Receptor Blocker
Therapeutic Indication :   Heart failure
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep out of reach of children
  • Do not store above 30°C

FAQs ABOUT VYMADA 50MG

What is VYMADA 50MG used for?

VYMADA 50MG is indicated to reduce the risk of cardiovascular death and hospitalization for heart failure in patients with chronic heart failure (New York Heart Association Class II-IV) and reduced ejection fraction.

What are the common side effects of taking VYMADA 50MG?

The most common side effects of taking VYMADA 50MG are dizziness, light-headedness (low blood pressure), signs of high levels of potassium in the blood (irregular heartbeat, muscle weakness), decrease in renal function, cough, diarrhea, signs of low red blood cells (anemia), tiredness, headache, fainting or spinning sensation. Consult your doctor immediately if any of the symptoms worsen.

Can VYMADA 50MG be used in pregnant women?

No, VYMADA 50MG is not recommended for use in early pregnancy and must not be used in pregnant women when more than 3 months pregnant, as it may cause serious harm to the baby. Consult your doctor before taking VYMADA 50MG if you think you may be pregnant.

Is VYMADA 50MG safe to use in liver disease patients?

VYMADA 50MG is not recommended in patients with severe liver disease and it should be used with caution in patients with liver disease. Consult your doctor before taking VYMADA 50MG.

What to do If I forget to take VYMADA 50MG?

You should take VYMADA 50MG immediately when you remember. If it is time for your next dose skip the missed dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.

REFERENCES

1. KD Tripathi MD. Cardiovascular drugs. Essentials of Medical Pharmacology. Seventh Edition. New Delhi, May 2013. Page – 508.

2. Loretta Fala. Entresto (Sacubitril/Valsartan): First-in-Class Angiotensin Receptor Neprilysin Inhibitor FDA Approved for Patients with Heart Failure. NCBI; PMC. Pubmed Central. National Library of Medicine, National Institute of Health. September 2018. [Accessed on 1st July 2021] ncbi.nlm.nih.gov/pmc/articles/PMC4636283/

3.  Peter Khalil, Ghazal Kabbach, Sarmad Said and Debabrata Mukherje. Entresto, a New Panacea for Heart Failure. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2018. [Accessed on 1st July 2021] https://pubmed.ncbi.nlm.nih.gov/29532764/

4. Novartis Pharmaceuticals UK Ltd. Electronic Medicines Compendium (EMC) [Revised in May 2021] [Accessed on 1st July 2021] https://www.medicines.org.uk/emc/files/pil.7751.pdf

5. Cipla Ltd. Azmarda Tablets (Sacubitril/Valsartan). Ciplamed. [Revised in March 2017] [Accessed on 1st July 2021] https://www.ciplamed.com/content/azmarda-tablets

USEFUL DIAGNOSTIC TESTS

  • Electrolyte panel

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    25 g
    Ingredient
    SACUBITRIL 24MG+VALSARTAN 26MG
    Hsn Code
    30049099
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Vymada 50mg Tablet 14'S

Vymada 50mg Tablet 14'S Mkt: Novartis Healthcare Pvt Ltd

M.R.P.: Rs.1,177.50
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