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INTRODUCTION
VOGLIZAR 0.3 TABLET contains Voglibose which belongs to the group of medicines called Anti-diabetics. It is used in the management of type 2 diabetes mellitus along with diet and exercise to improve post-prandial blood glucose levels (when only diet and/or exercise or oral hypoglycemic drugs or insulin preparation in addition to diet and/or exercise does not result in adequate glycemic control).
Type 2 diabetes is a chronic medical condition in which the body does not make enough insulin, or the produced insulin does not work well. Symptoms include excessive urination, excessive thirst, hunger, fatigue, and blurred vision.
Along management with VOGLIZAR 0.3 TABLET follow regular exercise and diet plan as advised by your doctor to achieve better results.
VOGLIZAR 0.3 TABLET is not recommended for use in patients having severe ketosis, in a state of diabetic coma or pre-coma, severe infection, before and after an operation, or with serious trauma and gastrointestinal obstruction.
VOGLIZAR 0.3 TABLET should be used with caution in patients undergoing abdominal laparotomy for gallstone ileus or have roemheld’s syndrome, stenosis, liver, and kidney problems and in elderly patients.
VOGLIZAR 0.3 TABLET is not recommended for use among pregnant, breastfeeding women, children, and adolescents.
The most common side effects of taking VOGLIZAR 0.3 TABLET are soft stools or diarrhea, flatulence, bloating, abdominal pain or discomfort, abdominal fullness, and nausea. Contact your doctor if any of the above symptoms worsen.
USES OF VOGLIZAR 0.3 TABLET
- Manage type 2 diabetes mellitus along with diet and exercise
HOW VOGLIZAR 0.3 TABLET WORKS
VOGLIZAR 0.3 TABLET works by inhibiting the intestinal enzymes that are responsible for breaking complex sugars into simple sugars such as glucose. This prevents the level of blood glucose from increasing very high immediately after meals.
DIRECTIONS FOR USE
Take VOGLIZAR 0.3 TABLET as advised by your physician.
For Tablet: Swallow VOGLIZAR 0.3 TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse VOGLIZAR 0.3 TABLET in the specified quantity of water as mentioned on the label or as directed by the doctor. Consume the mixture immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Continue to take VOGLIZAR 0.3 TABLET for the stipulated duration prescribed by your doctor to achieve better results.
SIDE EFFECTS OF VOGLIZAR 0.3 TABLET
COMMON
- soft stools or diarrhea
- flatulence
- abdominal pain or discomfort
- nausea
RARE
- headache
- anemia
- signs of low platelet levels (easy bleeding or bruising)
- signs of low white blood cells (repeated infections)
- numbness
- edema of the face
- blurred vision
- hot flushes
- general discomfort
- weakness
- signs of high potassium levels in blood (irregular heartbeat, muscle weakness, chest pain)
- excessive sweating
- hair loss
Stop taking VOGLIZAR 0.3 TABLET and contact your physician immediately if you experience any of the following side effects:
- signs of hypersensitivity reactions (severe skin rash with itching)
HOW TO MANAGE SIDE EFFECTS
Bloating
Eat smaller and frequent meals. Slowly eat and drink, and exercise regularly. If the symptom does not improve, contact your physician.
Diarrhea
Drink more fluids, such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own without consulting your physician.
Nausea And Vomiting
Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oil-rich or spicy foods. In case of no improvement, consult your doctor.
Stomach Pain
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heating pad on your stomach. If the symptom does not improve, contact your physician.
WARNING & PRECAUTIONS
PREGNANCY
Monitoring requiredVOGLIZAR 0.3 TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus. Consult your doctor before taking it.
BREASTFEEDING
ContraindicatedVOGLIZAR 0.3 TABLET is generally not recommended for use in breastfeeding women as it may passes through breast milk. Consult your doctor before taking it.
KIDNEY
Use with CautionVOGLIZAR 0.3 TABLET should be taken with caution in patients with kidney problems. Consult your doctor for advice.
LIVER
Use with CautionVOGLIZAR 0.3 TABLET should be taken with caution in patients with liver problems. Consult your doctor for advice.
ALLERGY
ContraindicatedDo not take VOGLIZAR 0.3 TABLET if you are allergic to Voglibose or to any ingredients of this medicine.
USE IN PEDIATRICS
Consult your doctorThe safety of VOGLIZAR 0.3 TABLET in children has not been established (no clinical experience). Consult your physician before taking VOGLIZAR 0.3 TABLET.
USE IN GERIATRICS
Use with CautionVOGLIZAR 0.3 TABLET should be used with caution in elderly patients. Consult your physician before taking VOGLIZAR 0.3 TABLET.
OTHERS
VOGLIZAR 0.3 TABLET is not recommended for use if you have:
- severe ketosis
- diabetic coma or pre-coma
- severe infection, after and before an operation
- serious trauma
- gastrointestinal obstruction
Before taking VOGLIZAR 0.3 TABLET, inform your physician if you:
- undergoing abdominal laparotomy for gallstone ileus
- have roemheld’s syndrome (cluster of cardiovascular symptoms stimulated by gastrointestinal changes)
- have stenosis (condition in which there is an abnormal narrowing in a blood vessel or other tubular organ or structure such as foramina and canals)
INTERACTIONS
A. Drug-Drug interactions:
Before taking VOGLIZAR 0.3 TABLET, inform your physician if you are taking any of the following medicines:
- other antidiabetic drugs (Ex. glipizide, tolbutamide, insulin) (used to treat diabetes)
- medicines used to treat heart problems (Ex. metoprolol, atenolol)
- medicine used to treat skin infection (Ex. salicylic acid)
- medicines used to treat depression (Ex. phenelzine, selegiline)
- medicine used to treat cholesterol (Ex. fenofibrate)
- epinephrine (medicine used to treat anaphylaxis reactions)
- adrenocorticotrophin (medicine used to treat disorders of the pituitary or adrenal glands like Cushing’s syndrome)
- thyroxine (medicine used to treat thyroid problems)
Overdosage:
If you or anyone else accidentally take too much of VOGLIZAR 0.3 TABLET, consult your physician immediately or visit the nearby hospital. The symptoms of overdosage are low blood sugar levels, abdominal discomfort and diarrhea.
SYNOPSIS
| Drug | : | Voglibose |
| Pharmacological Category | : | Alpha Glucosidase inhibitors |
| Therapeutic Indication | : | Type 2 diabetes mellitus |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep VOGLIZAR 0.3 TABLET out of reach of children
- Store at a room temperature
FAQs ABOUT VOGLIZAR 0.3 TABLET
Q: Can VOGLIZAR 0.3 TABLET cause diarrhea?
A: Diarrhea is the common side-effect of VOGLIZAR 0.3 TABLET. Drink more fluids, such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own to treat diarrhea without consulting your physician.
Q: Who should not take VOGLIZAR 0.3 TABLET?
A: VOGLIZAR 0.3 TABLET is not recommended for use in patients having severe ketosis, in a state of diabetic coma or pre-coma, severe infection, before and after an operation, or with serious trauma and gastrointestinal obstruction.
Q: What if I forget to take a dose of VOGLIZAR 0.3 TABLET?
A: You should take VOGLIZAR 0.3 TABLET immediately when you remember. If it is time for your next dose skip missed the dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
Q: How to take VOGLIZAR 0.3 TABLET?
A: Take VOGLIZAR 0.3 TABLET as advised by your physician. Your physician will decide the correct dose and duration for you depending upon your age, body weight, and disease condition.
Q: What are the common side effects of VOGLIZAR 0.3 TABLET?
A: The most common side effects of taking VOGLIZAR 0.3 TABLET are soft stools or diarrhea, flatulence, bloating, abdominal pain or discomfort, abdominal fullness, and nausea. Contact your physician if any of the symptoms worsen.
Q: What happens when I take an overdose of VOGLIZAR 0.3 TABLET?
A: If you or anyone else accidentally take too much of VOGLIZAR 0.3 TABLET, consult your physician immediately or visit the nearby hospital. The symptoms of overdosage are low blood sugar levels, abdominal discomfort, and diarrhea.
REFERENCES
1. Alvin C. Powers and David D’Alessio. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018. Page – 863-886.
2. KD. Tripathi. Insulin, Oral Hypoglycemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 258-281.
3. Ajay S. Dabhi, Nikita R. Bhatt, and Mohit J. Shah. Voglibose: An Alpha Glucosidase Inhibitor. Journal of Clinical and Diagnostic Research. December 2013 [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919386/
4. Sanjay Kalra, A Panneer Selvam, Amish V Shah, Kudugunti Neelaveni, Navneet Agrawal, Sambit Das, Vinay K Dhandhania, Subodh Jain, Pankaj Kumar Jha and Neha Rava. Prospective Multicenter Observational Study of Voglibose in Type 2 Diabetes-Victory. Journal of US Endocrinology. January 2020 [Accessed on 21st June 2022] https://www.researchgate.net/publication/342024938_Prospective_Multicenter_Observational_Study_of_Voglibose_in_Type_2_Diabetes-VICTORY
5. Cipla Ltd. Prandal MD Tablets (Voglibose). Cilpamed. [Revised in August 2015] [Accessed on 21st June 2022] https://www.ciplamed.com/content/prandial-md-tablets
6. Amigoz life sciences. Voglibose Tablets. [Accessed on 21st June 2022] http://amigozlife.com/voglibose-tablets.html
7. DM Pharma. Voglibose Tablet. Antidiabetic agents. [Accessed on 21st June 2022] http://www.dmpharma.co.in/Voglibose.html
USEFUL DIAGNOSTIC TESTS
- Glucose-Fasting Blood
- Glucose-Postprandial Blood
- Glycosylated Hemoglobin
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 18 Oct 2023 | 05:02 PM(IST)
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