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INTRODUCTION
VOGLI RAPID 0.2/1 TABLET is a combination of Repaglinide and Voglibose which belongs to the group of medicines called Anti-diabetic agents. VOGLI RAPID 0.2/1 TABLET is used as an adjunct (to diet and exercise) to treat type 2 Diabetes Mellitus in patients to help control blood sugar level.
VOGLI RAPID 0.2/1 TABLET is not recommended for use in patients allergic to Repaglinide and/or Voglibose. It is also not recommended for use in patients with type 1 diabetes, diabetic ketoacidosis (serious complication of diabetes), severe infection (before/after an operation), gastrointestinal obstruction (bowel obstruction) and/or moderate to severe liver disease.
Before taking VOGLI RAPID 0.2/1 TABLET, inform your doctor if you are scheduled for a major surgery and/or have severe illness, fever, trauma, infection, chronic intestinal disease, kidney problems (such as mild/moderate/severe renal impairment).
VOGLI RAPID 0.2/1 TABLET is generally not recommended for use during pregnancy and in women planning for pregnancy. It is also not recommended for use in breastfeeding women.
VOGLI RAPID 0.2/1 TABLET is not indicated for use in children & adolescents (aged below 18 years) and in elders (aged above 75 years). Consult and inform your doctor before taking the medicine.
The most common side effects of taking VOGLI RAPID 0.2/1 TABLET are hypoglycaemia (low blood sugar), abdominal pain/discomfort, diarrhoea, headache, fever, muscle pain and/or tenderness. Consult and inform your doctor if any of these symptoms worsen.
USES OF VOGLI RAPID 0.2/1 TABLET
- Adjunct to diet and exercise to treat type-2 diabetes mellitus in affected individuals
HOW VOGLI RAPID 0.2/1 TABLET WORKS
VOGLI RAPID 0.2/1 TABLET is a combination of Repaglinide and Voglibose where Repaglinide increases the amount of insulin released by the pancreas and Voglibose inhibits the action of α-glucosidase (an intestinal enzyme responsible for breaking down complex sugars into simple sugars) which results in lowering the blood glucose level and thus treating type-2 diabetes mellitus in affected individuals.
DIRECTIONS FOR USE
Take VOGLI RAPID 0.2/1 TABLET as advised by your physician. Swallow VOGLI RAPID 0.2/1 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF VOGLI RAPID 0.2/1 TABLET
COMMON
- signs of hypoglycaemia (low blood sugar) such as rapid heart rate, shaking, sweating
- abdominal pain/discomfort, diarrhoea
- signs of gastritis (inflammation of stomach) such as upper abdomen pain, nausea, vomiting
- swelling of face/arms/legs
- headache, fever
- sore throat
- sinusitis (sinus inflammation)
- signs of hypertriglyceridaemia (high level of fat blood) such as stomach pain, confusion and/or memory loss
- muscle pain and tenderness
- periarthritis (swelling around joints)
RARE
- acute coronary syndrome
- anaemia
- thrombocytopenia (low platelet level)
- leucopoenia (low level of white blood cells in blood)
Stop taking this medicine and contact your doctor immediately if you experience any of the following side effects:
- signs of an anaphylactic reaction (life-threatening allergic reaction) such as swelling, difficulty in breathing, rapid heartbeat, feeling dizzy and/or sweating
- signs of hypersensitivity reaction of skin such as erythema, itching, rashes and/or itchy welts
HOW TO MANAGE SIDE EFFECTS
Diarrhea:
Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult and inform your doctor if the symptom worsens.
Headache:
If VOGLI RAPID 0.2/1 TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking VOGLI RAPID 0.2/1 TABLET. If it lasts more than a week or severe, inform your doctor.
WARNING & PRECAUTIONS
PREGNANCY
VOGLI RAPID 0.2/1 TABLET is generally not recommended for use during pregnancy and in women planning for pregnancy. Consult and inform your doctor before taking VOGLI RAPID 0.2/1 TABLET.
BREASTFEEDING
VOGLI RAPID 0.2/1 TABLET is generally not recommended for use in breastfeeding women. Consult and inform your doctor before taking VOGLI RAPID 0.2/1 TABLET.
DRIVING AND USING MACHINES
Do not drive or operate machines if you experience signs of high/low blood sugar since it can endanger you/others.
ALCOHOL
Avoid consumption of alcohol while taking VOGLI RAPID 0.2/1 TABLET since it may alter the effect of the medicine.
KIDNEY
VOGLI RAPID 0.2/1 TABLET should be used with caution in patients with kidney problems such as mild, moderate/severe renal impairment and in patients who are undergoing dialysis. Consult and inform your doctor before taking the medicine.
LIVER
VOGLI RAPID 0.2/1 TABLET is not recommended for use in patients with moderate to severe liver disease. Consult and inform your doctor before taking the medicine.
ALLERGY
Do not take VOGLI RAPID 0.2/1 TABLET if you are allergic to Repaglinide, Voglibose and/or any other ingredients of this medicine.
OTHERS
VOGLI RAPID 0.2/1 TABLET is not recommended for use if you:
- suffer from type 1 diabetes and/or diabetic ketoacidosis (serious complication of diabetes) associated with/without coma
- suffer from severe infection before/after an operation
- have gastrointestinal obstruction (bowel obstruction)
Before taking VOGLI RAPID 0.2/1 TABLET, inform your doctor if you:
- are scheduled for a major surgery
- have recently suffered a severe illness
- are suffering from fever, trauma and/or infection
- have a history of laparotomy (surgical incision done into an abdominal cavity for a major surgery)/ileus (condition marked by impaired bowel function)
- suffer from chronic intestinal disease (accompanied by disturbance in digestion and absorption)
Use in Paediatrics:
VOGLI RAPID 0.2/1 TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult and inform your doctor before taking VOGLI RAPID 0.2/1 TABLET.
Use in Geriatrics:
VOGLI RAPID 0.2/1 TABLET is not recommended for use in elderly patients (aged above 75 years). Consult and inform your doctor before taking VOGLI RAPID 0.2/1 TABLET.
INTERACTIONS
A. Drug - Drug interactions:
Before taking VOGLI RAPID 0.2/1 TABLET, inform your doctor if you are taking any of the following medicine:
- gemfibrozil (medicine used to lower increased fat levels in the blood)
- monoamine oxidase inhibitors (used to treat depression) Ex. phenelzine, selegiline
- beta blockers (used to treat high blood pressure or heart conditions) Ex. acebutolol, atenolol
- ACE-inhibitors (used to treat heart conditions) Ex. benazepril, captopril
- salicylates (medicines used to reduce pain, fever and inflammation) Ex. aspirin
- octreotide (used to treat cancer)
- nonsteroidal anti-inflammatory drugs (medicines used to reduce fever and pain) Ex. ibuprofen, naproxen
- steroids (used to treat inflammation) Ex. prednisolone, fluticasone
- oral contraceptives (used to prevent pregnancy) Ex. desogestrel and ethinyl estradiol
- thiazides (used to treat high blood pressure) Ex. chlorothiazide, chlorthalidone
- danazol (used to treat breast cysts and endometriosis)
- thyroid products (used to treat low levels of thyroid hormones)
- sympathomimetics (used to treat asthma) Ex. salbutamol, terbutaline
- clarithromycin, trimethoprim, rifampicin (antibiotics used to treat bacterial infections)
- itraconazole, ketoconazole (medicines used to treat fungal infections)
- ciclosporin (used to prevent rejection of transplanted organ)
- deferasirox (used to reduce chronic iron overload)
- clopidogrel (prevents blood clots)
- phenytoin, carbamazepine, phenobarbital (used to treat epilepsy)
- St. john’s wort (herbal medicine)
Overdosage:
If you or anyone else accidentally take too much of VOGLI RAPID 0.2/1 TABLET, consult and inform your doctor immediately or visit the nearby hospital. Symptoms of overdose are hypoglycaemia with associated signs such as dizziness, sweating, tremor, headache, loss of consciousness, seizure and/or coma.
SYNOPSIS
| Drug | : | Repaglinide, Voglibose |
| Pharmacological Category | : | Antidiabetic agents |
| Therapeutic Indication | : | Type-2 diabetes mellitus |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep VOGLI RAPID 0.2/1 TABLET out of reach of children
- Do not store VOGLI RAPID 0.2/1 TABLET above 30°C
FAQs ABOUT VOGLI RAPID 0.2/1 TABLET
What is VOGLI RAPID 0.2/1 TABLET used for?
VOGLI RAPID 0.2/1 TABLET is a combination of Repaglinide and Voglibose which belongs to the group of medicines called Anti-diabetic agents. It is generally used as an adjunct (to diet and exercise) to treat type 2 Diabetes Mellitus in patients to help control blood sugar level.
What are the side effects of VOGLI RAPID 0.2/1 TABLET?
The most common side effects of taking VOGLI RAPID 0.2/1 TABLET are hypoglycaemia (low blood sugar), abdominal pain/discomfort, diarrhoea, headache, fever, muscle pain and/or tenderness. Consult and inform your doctor if any of these symptoms worsen.
How VOGLI RAPID 0.2/1 TABLET works?
VOGLI RAPID 0.2/1 TABLET is a combination of Repaglinide and Voglibose where Repaglinide increases the amount of insulin released by the pancreas and Voglibose inhibits the action of α-glucosidase (an intestinal enzyme responsible for breaking down complex sugars into simple sugars) which results in lowering the blood glucose level and thus treating type-2 diabetes mellitus in affected individuals.
How VOGLI RAPID 0.2/1 TABLET is taken?
Take VOGLI RAPID 0.2/1 TABLET as advised by your physician. Swallow VOGLI RAPID 0.2/1 TABLET with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Can VOGLI RAPID 0.2/1 TABLET be used in children?
No, VOGLI RAPID 0.2/1 TABLET is not recommended for use in children and adolescents (aged below 18 years). Consult and inform your doctor before taking VOGLI RAPID 0.2/1 TABLET.
REFERENCES
1. K.D. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page- 273, 277.
2. Repaglinide. NIH National Library of Medicine. National Center for Biotechnology Information. StatPearls [Internet]. [Revised in July 2022] [Accessed on 11th April 2022] https://www.ncbi.nlm.nih.gov/books/NBK559305/
3. Ajay S. Dabhi,Nikita R. Bhatt, Mohit J. Shah. Voglibose: An Alpha Glucosidase Inhibitor. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in December 2013] [Accessed on 11th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919386/
4. Torrent Pharmaceuticals Ltd. EUREPA-V. [Revised in December 2019] [Accessed on 11th April 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2885.pdf
5. Medley Pharmaceuticals Ltd. Vogli-Rapid. [Accessed on 11th April 2022] https://www.medleylab.com/product/glycekare/anti-diabetic.html
USEFUL DIAGNOSTIC TESTS
- Glucose - Fasting Blood
- Glucose - Postprandial Blood
- Glycosylated Hemoglobin
AUTHOR DETAILS
Written By Dr. K .AZEEM HUSSAIN, B.D.S
Last updated on 24 Nov 2022 | 07:24 PM(IST)
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