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INTRODUCTION
VILDRACE 50 TABLET contains Vildagliptin which belongs to group of medicines called Oral Anti-diabetics. It is used in adults to treat type 2 diabetes which helps to control the blood sugar level when diet and exercise becomes insufficient to control the disease.
Type 2 diabetes mellitus is a medical condition in which the body does not make enough insulin or if the insulin that the body makes is insufficient leading to high blood sugar level in the body. It is generally characterized by symptoms such as excessive thirst, frequent urination, excessive hunger, unintended weight loss and tiredness.
Along treatment with VILDRACE 50 TABLET, your doctor might advise you to follow the diet and/or exercise which is beneficial. Avoid consumption of alcohol while taking VILDRACE 50 TABLET because it might lead to low blood glucose levels.
Before taking VILDRACE 50 TABLET, inform your doctor if you are on dialysis or have diabetic ketoacidosis (serious complication of diabetes), pancreatic disease, heart failure and liver or kidney disease.
VILDRACE 50 TABLET is not recommended for use in pregnant and breast-feeding women, which is also not recommended for use in children and adolescents (aged below 18 years). It should be used with caution in elderly patients (aged 65 years and above).
The side effects of taking VILDRACE 50 TABLET are dizziness, headache, joint pain and constipation. Consult your doctor if any of the side effects worsen.
USES OF VILDRACE 50 TABLET
- Treats type 2 diabetes
HOW VILDRACE 50 TABLET WORKS
VILDRACE 50 TABLET controls blood glucose level by acting on the pancreas to produce more insulin and less glucagon which leads to low production of blood sugar levels resulting in controlled blood glucose levels.
DIRECTIONS FOR USE
Take VILDRACE 50 TABLET as advised by your physician. Do not crush or chew VILDRACE 50 TABLET. Swallow the medicine with a glass of water. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF VILDRACE 50 TABLET
COMMON
- dizziness
UNCOMMON
- headache
- constipation
- swollen hands, ankle or feet (oedema)
- joint pain
- signs of low blood glucose levels such as excessive hunger, sweating, tiredness
RARE
Stop taking VILDRACE 50 TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of angioedema (such as swollen face, tongue or throat, difficulty swallowing, difficulty in breathing, sudden onset rash or hives)
- signs of liver disease (hepatitis) such as loss of appetite or dark-coloured urine, yellow skin and eyes, nausea
- signs of inflammation of the pancreas such as severe and persistent pain in the abdomen (stomach area), nausea and vomiting
HOW TO MANAGE SIDE EFFECTS
Headache:
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Dizziness:
Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.
Constipation:
Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not improve, consult your doctor.
WARNING & PRECAUTIONS
PREGNANCY
VILDRACE 50 TABLET is not recommended for use in pregnant women. Consult your doctor before taking it.
BREASTFEEDING
VILDRACE 50 TABLET is not recommended for use in breastfeeding women or women who plan to breast-feed. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizziness after taking VILDRACE 50 TABLET.
ALCOHOL
Avoid consumption of alcohol while taking VILDRACE 50 TABLET because it might lead to hypoglycemia (lowering of blood glucose levels).
KIDNEY
VILDRACE 50 TABLET should be used with caution in patients with moderate or severe kidney disease and in patients who are undergoing dialysis. Consult your doctor before taking it.
LIVER
VILDRACE 50 TABLET should be used with caution in patients with liver disease. Consult your doctor before taking it.
ALLERGY
Do not take VILDRACE 50 TABLET if you are allergic to Vildagliptin or any other ingredients of this medicine.
HEART DISEASE
VILDRACE 50 TABLET should be used with caution in patients suffering from heart failure. Consult your doctor before taking it.
OTHERS
Before taking VILDRACE 50 TABLET, inform your doctor if you:
- have type 1 diabetes (i.e. your body does not produce insulin)
- have a condition called diabetic ketoacidosis (serious complication of diabetes)
- have intolerance to certain sugars
- had or have a disease of the pancreas
Use in Pediatrics:
VILDRACE 50 TABLET is not recommended for use in children and adolescents up to 18 years of age. Consult your child’s doctor for advice.
Use in Geriatrics:
VILDRACE 50 TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking it.
INTERACTIONS
A. Drug - Drug interactions:
Before taking VILDRACE 50 TABLET, inform your doctor if you are taking any of the following medicines:
- oral antidiabetics (medicine used to treat type 2 diabetes) Ex. sulphonylureas such as gliclazide, glipizide
- digoxin (used to treat heart failure)
- warfarin (used to treat blood clot)
- amlodipine, ramipril, valsartan and angiotensin-converting enzyme (ACE) inhibitors (used to treat high blood pressure) such as captopril, enalapril, fosinopril
- simvastatin (used to reduce high cholesterol levels)
- thiazides or other diuretics (medicines used to treat high blood pressure) Ex. chlorothiazide, chlorthalidone, hydrochlorothiazide
- corticosteroids (used to treat inflammation) Ex. prednisolone
- certain medicines affecting nervous system such as antidepressants Ex. clomipramine, amitriptyline
- thyroid medicines (used to lower thyroid levels) Ex. levothyroxine
Over dosage:
If you or anyone else accidentally takes too much of VILDRACE 50 TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of VILDRACE 50 TABLET are muscle pain, mild and transient paraesthesia (burning and prickling sensation in hands and legs), fever, oedema (swelling in arms and legs) and laboratory abnormalities such as transient increase in lipase levels, increases in creatine phosphokinase (CPK), aspartate aminotransferase (AST), C-reactive protein (CRP) and myoglobin levels.
SYNOPSIS
| Drug | : | Vildagliptin |
| Pharmacological Category | : | Dipeptidyl peptidase-4 (DPP-4) inhibitors |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep VILDRACE 50 TABLET out of reach of children
- Store at room temperature
FAQs ABOUT VILDRACE 50 TABLET
Can VILDRACE 50 TABLET be used to treat diabetes mellitus?
Yes, VILDRACE 50 TABLET lowers blood glucose levels and it is specifically used to treat type II diabetes mellitus which is a medical condition where the body does not make enough insulin or if the produced insulin that the body makes is not optimal leading to increased blood glucose levels in the body. Consult your doctor before taking VILDRACE 50 TABLET.
Can I take VILDRACE 50 TABLET along with other hypoglycemic drugs like metformin or glimepiride?
Using VILDRACE 50 TABLET along with other hypoglycemic drugs like metformin, glimiperide may drastically lower your blood glucose levels. So, be cautious and inform your doctor before taking any other anti-diabetic medicines.
Does taking VILDRACE 50 TABLET cause weight gain?
No, VILDRACE 50 TABLET has no effect on weight gain. Moreover, these kinds of medicines delay gastric emptying and make you feel satiety (stomach fullness). These further decreases hunger. So, basically VILDRACE 50 TABLET has no effect or it does not influence weight gain.
How does VILDRACE 50 TABLET work?
VILDRACE 50 TABLET controls blood glucose level by acting on the pancreas to produce more insulin and less glucagon which leads to low production of blood sugar levels resulting in controlled blood glucose levels.
Does VILDRACE 50 TABLET cause dizziness?
Yes, VILDRACE 50 TABLET may cause dizziness in some individuals. To manage this effect, lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the symptom gets worse.
REFERENCES
1 KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 275
2. B Ahren , A Schweizer, S Dejager, E B Villhauer, B E Dunning, J E Foley. Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans. NIH National Library of Medicine. National Center for Biotechnology Information.PubMed.gov. [Revised in September 2011] [Accessed on 14th April 2022] https://pubmed.ncbi.nlm.nih.gov/21507182/
3. Kalyan Kumar Gangopadhyay and Parminder Singh. Consensus Statement on Dose Modifications of Antidiabetic Agents in Patients with Hepatic Impairment. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in March 2017] [Accessed on 14th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367241/
4. Novartis Europharm Limited. Electronic Medicines Compendium (EMC) [Revised in October 2020] [Accessed on 14th April 2022] https://www.medicines.org.uk/emc/files/pil.6225.pdf
5. Novartis Pharma GmbH. European Medicines Agency (EMA). [Revised in July 2012] [Accessed on 14th April 2022] https://ec.europa.eu/health/documents/community-register/2007/2007092629572/anx_29572_en.pdf
USEFUL DIAGNOSTIC TESTS
- HA1C Test
- Fasting Blood Sugar Test
- Random Blood Sugar Test
- Glucose Tolerance Test
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 06 Oct 2022 | 05:39 PM(IST)
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