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INTRODUCTION
VILDALOG 50MG contains vildagliptin which belongs to the group of medicines called oral anti-diabetic agents. It is used to treat type 2 diabetes mellitus in adults, when it cannot be controlled by diet or exercise. Type 2 diabetes mellitus is a chronic condition in which your body does not make enough insulin, and or the insulin that your body produces does not work as well as it should.
It helps to control the elevated sugar levels in your blood. It works by making your pancreas secrete more insulin, a hormone which is involved in glucose absorption and less glucagon. Your doctor might prescribe VILDALOG 50MG either alone or in combination with other antidiabetic medicines, which you are already taking. Along with the treatment, it is important to follow simple diet and/or exercise which has been recommended for you.
Avoid smoking and alcohol consumption while taking this medicine. The most common side effects of taking this medicine are headache, dizziness, tremor and weakness. Before taking this medicine, inform your doctor if you have any liver, kidney or pancreatic disorders. Consult your doctor, before taking this medicine if you are pregnant or breastfeeding. This medicine is not recommended for use in children and adolescents up to 18 years of age.
USES OF VILDALOG 50MG
- Type 2 diabetes mellitus
HOW VILDALOG 50MG WORKS
VILDALOG 50MG works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduce the fasting and post meal sugar level.
DIRECTIONS FOR USE
Take this medicine as directed by your physician. Swallow the medicine as whole with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.
SIDE EFFECTS OF VILDALOG 50MG
SERIOUS
- angioedema (swollen face, tongue or throat, difficulty in swallowing, difficulty in breathing, sudden onset rash or hives)
- symptoms of hepatitis (yellow skin and eyes, nausea, loss of appetite or dark-colored urine)
- pancreatitis (inflammation of pancreas)
COMMON
- trembling
- headache, dizziness
- nausea
- weakness
- weight increase
- swollen hands, ankle or feet
- excessive sweating
- chills
- heartburn
HOW TO MANAGE SIDE EFFECTS
Feeling sick (nausea):
Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.
Weight gain:
Try to exercise more regularly, for e.g., by going for a daily walk or run.
Headache:
Rest and drink plenty of fluids. Do not drink too much alcohol. Ask your doctor to recommend a painkiller.
Dizziness:
Try to rest and relax. Avoid travelling or riding bike while feeling dizzy. Avoid consumption of alcohol. If the symptoms worsen, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
VILDALOG 50MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
VILDALOG 50MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machines if your ability is affected by this medicine.
ALCOHOL
Avoid consumption of alcohol while taking this medicine.
KIDNEY
VILDALOG 50MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
VILDALOG 50MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
Do not take this medicine if you are allergic to vildagliptin.
HEART DISEASE
VILDALOG 50MG should be taken with caution in patients with heart failure. Consult your doctor for advice.
INTERACTIONS
Talk to your doctor, if you are taking,
- other oral anti-diabetic medicine (such as glimepiride, glibenclamide)
- thiazides or other diuretics (used to increase urine output)
- corticosteroids (used to treat inflammation)
- thyroid medicines (used to treat thyroid disorders)
- certain medicines affecting the nervous system
SYNOPSIS
| Drug | : | Vildagliptin |
| Pharmacological Category | : | Oral antidiabetic agent |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
MORE INFORMATION
Store at room temperature and keep out of reach of children.
FAQs ABOUT VILDALOG 50MG
Can VILDALOG 50MG be crushed?
No. Swallow the medicine as whole with a drink of water. Do not crush or chew the medicine.
Can VILDALOG 50MG be used during pregnancy?
No. Do not take this medicine if you are pregnant, or if you are trying to become pregnant. Consult your doctor for advice.
Can VILDALOG 50MG be used in children?
No. This medicine is not recommended for use in children and adolescents up to 18 years of age.
REFERENCES
1. Martha S. Nolte Kennedy, MD, & Umesh Masharani. Pancreatic Hormones & Antidiabetic Drugs. Basic & Clinical Pharmacology. 14th Edition. Mc Graw Hill Education Lang: 2018. Page - 763.
2. KD Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of Medical Pharmacology. Seventh edition. Page - 275.
3. Novartis Pharmaceuticals. Long-term Safety Study of Vildagliptin in Patients With Type 2 Diabetes. NIH U.S. National Library of medicine Clinical trials.gov. June 2015. [Accessed 27th October 2020] https://clinicaltrials.gov/ct2/show/NCT01159249
4. Emanuele Bosi, Riccardo Paolo Camisasca, Carole Collober, Erika Rochotte and Alan J. Garber. Effects of Vildagliptin on Glucose Control Over 24 Weeks in Patients With Type 2 Diabetes Inadequately Controlled With Metformin. American Diabetic association. April 2007. [Accessed 27th October 2020] https://care.diabetesjournals.org/content/30/4/890
5. Novartis Farmacéutica SA. Electronic Medicines Compendium (EMC) [Revised on October 2020] [Accessed 27th October 2020] https://www.medicines.org.uk/emc/files/pil.9967.pdf
6. Novartis Farmacéutica SA. Electronic Medicines Compendium (EMC) [Revised on October 2020] [Accessed 27th October 2020] https://www.medicines.org.uk/emc/files/pil.6225.pdf
USEFUL DIAGNOSTIC TESTS
Glucose - Fasting Blood
Glucose - Postprandial Blood
Glycosylated Hemoglobin
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