VILDALIVE M 500 Tablet 14's

Diabetes Rx required
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Best Price* ₹ 119.20 MRP ₹ 149.00
(Inclusive of all taxes) *14 Tablet(s) in a Strip * Mkt: Allysia Lifesciences Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

VILDALIVE M 500 is a combination of Metformin and Vildagliptin which belongs to the group of medicines called Antidiabetic agents. VILDALIVE M 500 is used to treat type 2 diabetes (also known as non-insulin dependent diabetes mellitus) in adult patients, whose diabetes cannot be controlled by diet and exercise alone and/or with other medicines used to treat diabetes (insulin or sulphonylureas such as glimepiride, glipizide). Type 2 diabetes is a chronic medical condition in which the body does not make enough insulin, or the produced insulin does not work well. Symptoms include excessive urination, excessive thirst, hunger, fatigue, and blurred vision.

Metformin decreases hepatic glucose production and intestinal absorption of glucose and improves insulin sensitivity (increases peripheral glucose uptake and utilization). Vildagliptin works by making the pancreas produce more insulin and less glucagon, thus leading to a decrease in blood glucose levels.  Along treatment with VILDALIVE M 500, follow regular exercise and diet plan as advised by your doctor to achieve better results.

Before taking VILDALIVE M 500 inform your doctor if you have liver, kidney, or heart problems. It should be used during pregnancy only if advised by your doctor and not recommended for use in breast-feeding women. VILDALIVE M 500 is not suitable for use in children and adolescents under 18 years of age and it should be used with caution in elderly patients (65 years of age and above). Avoid consumption of alcohol during treatment with VILDALIVE M 500 as it may increase the risk of lactic acidosis. The most common side effects of taking VILDALIVE M 500 are nausea, vomiting, stomach pain, headache, low blood sugar and diarrhoea. Contact your doctor if any of the symptoms worsen.

USES OF VILDALIVE M 500

  • To treat type II diabetes mellitus (whose diabetes cannot be controlled by diet and exercise alone and/or with other medicines used to treat diabetes)

HOW VILDALIVE M 500 WORKS

VILDALIVE M 500 helps to control the level of sugar in the blood, where metformin works by helping the body to make better use of insulin and vildagliptin works by making the pancreas produce more insulin and less glucagon.

DIRECTIONS FOR USE

Take VILDALIVE M 500 as directed by your physician. Take this medicine with or just after the food, swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon age and health condition. Do not stop taking VILDALIVE M 500 without informing your doctor.    

SIDE EFFECTS OF VILDALIVE M 500

COMMON

  • nausea
  • vomiting
  • diarrhoea
  • stomach pain
  • loss of appetite
  • dizziness
  • headache
  • metallic taste
  • low blood glucose
  • uncontrolled trembling

UNCOMMON

  • joint pain, tiredness
  • constipation
  • swollen hands, ankle, or feet (oedema)

RARE

Stop taking VILDALIVE M 500 and contact your doctor immediately if you experience any of the following side effects:  

  • symptoms of lactic acidosis (such as vomiting, stomach pain, decreased heartbeat, difficulty in breathing, muscle cramps, general weakness with severe tiredness or reduced body temperature)
  • signs of inflamed pancreas (severe and persistent pain in the abdomen with or without nausea or vomiting)
  • signs of liver disease like hepatitis (such as yellowing of skin and eyes, nausea, loss of appetite or dark-colored urine)
  • severe allergic reactions called angioedema (such as swelling of the face, lips, mouth, tongue, or throat that may lead to difficulty in breathing or swallowing)
  • condition that may be associated with dehydration such as severe vomiting, diarrhoea, fever, exposure to heat or if you drink less fluid than normal

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.

Constipation:

Take fiber rich foods in your diet such as fresh fruits, vegetables and whole grain cereals, and drink plenty of fluids. Exercise more regularly and stay active. Consult your doctor if the symptom did not improve.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve on its own.

Nausea and vomiting:

Stick to simple meals. Avoid eating oily, fried, or spicy food. Do not perform any strenuous activities immediately after eating. Consult your doctor if the symptom did not improve.

Headache:

Rest and relax. Drink sufficient amount of fluids such as water. Apply a pain-relieving balm on the head if required. Consult your doctor if the symptom did not improve.

WARNING & PRECAUTIONS

PREGNANCY

VILDALIVE M 500 is generally not recommended for use in pregnant women unless it is considered clearly necessary. Consult your doctor before taking VILDALIVE M 500.

BREASTFEEDING

VILDALIVE M 500 is not recommended for use in breastfeeding women. Consult your doctor before taking VILDALIVE M 500.  

DRIVING AND USING MACHINES

Do not drive or operate any machines if you experience dizziness after taking VILDALIVE M 500.      

ALCOHOL

Consumption of alcohol is not recommended during treatment with VILDALIVE M 500 since it may increase the risk of lactic acidosis.

KIDNEY

VILDALIVE M 500 is not recommended in patients with severely reduced kidney function. Consult your doctor before taking VILDALIVE M 500.   

LIVER

VILDALIVE M 500 is not recommended in patients with liver disease. Consult your doctor before taking VILDALIVE M 500.

ALLERGY

Do not take VILDALIVE M 500 if you are allergic (hypersensitive) to Metformin or Vildagliptin.

HEART DISEASE

VILDALIVE M 500 is not recommended in patients who recently had heart attack or heart failure or any signs of heart problems such as serious problems with blood circulation or difficulty in breathing. Consult your doctor before taking VILDALIVE M 500.

OTHERS

VILDALIVE M 500 is not recommended for you, if you have:

  • type 1 diabetes mellitus
  • uncontrolled diabetes (with severe low blood sugar levels, nausea, vomiting, diarrhoea, rapid weight loss, ketoacidosis, or lactic acidosis)
  • severe infection or seriously dehydrated
  • are going to have a contrast x-ray (a specific type of x-ray involving an injectable dye)

Before taking VILDALIVE M 500, inform your doctor if you have or had:

  • disease of the pancreas
  • going to undergo any surgery
  • vitamin B12 deficiency
  • malnutrition with adrenal or pituitary insufficiency

Use in pediatrics:

VILDALIVE M 500 is not recommended for use in children and adolescents less than 18 years of age due to lack of safety and effectiveness. Consult with your doctor for advice.

Use in geriatrics:

VILDALIVE M 500 should be used with caution in elderly patients above 65 years of age, especially in patients with impaired kidney function. Your doctor will adjust the dose depending upon kidney function and your kidney function will be monitored regularly. Consult with your doctor before taking VILDALIVE M 500.

INTERACTIONS

A. Drug-Drug interactions:

Before taking VILDALIVE M 500 inform to your doctor, if you are taking any of these medicines:

  • glucocorticoids such as dexamethasone, prednisolone (treats inflammation)
  • beta-2 agonists such as albuterol, terbutaline (treats respiratory disorders)
  • diuretics such as chlorthalidone, hydrochlorothiazide (used to increase urine production)
  • ibuprofen and celecoxib (treats pain and inflammation)
  • angiotensin-converting enzyme (ACE) inhibitors (Ex. enalapril, lisinopril) and angiotensin II receptor antagonists (Ex. losartan, telmisartan) (treats high blood pressure)
  • medicines affecting the nervous system and thyroid
  • other medicines used to treat diabetes (Ex. glimepiride, glipizide)
  • ranolazine (treats chest pain)
  • dolutegravir (treats HIV infection)
  • vandetanib (treats medullary thyroid cancer)
  • cimetidine (treats heartburn and peptic ulcers)

Overdosage:

If you or anyone else accidentally take too much of VILDALIVE M 500, consult your doctor immediately. Overdosage symptoms of VILDALIVE M 500 might include low blood sugar levels, lactic acidosis, muscle pain, mild and transient burning or tickling sensation in body, fever, and edema.

SYNOPSIS

Drug :   Metformin, Vildagliptin
Pharmacological Category :   Antidiabetic agent (Biguanides & Dipeptidyl Peptidase 4 Inhibitor)                                             
Therapeutic Indication :  

Type 2 Diabetes mellitus

Dosage Forms :   Tablet

MORE INFORMATION

  • Keep VILDALIVE M 500 out of reach of children
  • Do not store above 30°C

FAQs ABOUT VILDALIVE M 500

What is VILDALIVE M 500 used for?

VILDALIVE M 500 is used to treat type 2 diabetes (also known as non-insulin dependent diabetes mellitus) in adult patients, whose diabetes cannot be controlled by diet and exercise alone and/or with other medicines used to treat diabetes (insulin or sulphonylureas such as glimepiride, glipizide).

Can VILDALIVE M 500 be used in elderly patients?

VILDALIVE M 500 should be used with caution in elderly patients above 65 years of age, especially in patients with impaired kidney function. Your doctor will adjust the dose depending upon kidney function and your kidney function will be monitored regularly. Consult with your doctor before taking VILDALIVE M 500. 

Is VILDALIVE M 500 safe to use in patients with heart problems?

VILDALIVE M 500 is not recommended in patients who recently had heart attack or heart failure or any signs of heart problems such as serious problems with blood circulation or difficulty in breathing. Consult your doctor before taking VILDALIVE M 500.

What are the most common side effects of taking VILDALIVE M 500?

The most common side effects of taking VILDALIVE M 500 are nausea, vomiting, stomach pain, headache, dizziness, loss of appetite, metallic taste, uncontrolled trembling, low blood sugar and diarrhoea. Contact your doctor if any of the symptoms worsen.

Can I consume alcohol while taking VILDALIVE M 500?

Consumption of alcohol is not recommended during treatment with VILDALIVE M 500 since it may increase the risk of lactic acidosis. Consult your doctor before taking VILDALIVE M 500 if you are alcoholic or with history of alcoholism.

REFERENCES

1. KD Tripathi MD. Hormones and related drugs. Essentials of Medical Pharmacology. Seventh edition. New Delhi, May 2013. Page – 274.

2. Paresh Ved and Samrat Shah. Evaluation of vildagliptin and fixed dose combination of vildagliptin and metformin on glycemic control and insulin dose over 3 months in patients with type 2 diabetes mellitus. March 2012. [Accessed on 30th June 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354946/

3. Serge Halimi, Anja Schweizer, Biljana Minic, James Foley and Sylvie Dejage. Combination treatment in the management of type 2 diabetes: focus on vildagliptin and metformin as a single tablet. March 2008. [Accessed on 30th June 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515409/

4. Novartis Pharma GmbH. Electronic Medicines Compendium (EMC) [Revised in August 2021] [Accessed on 30th June 2021] https://www.medicines.org.uk/emc/files/pil.6226.pdf

5. Cipla Ltd. VYSOV-M Tablets (Vildagliptin + Metformin hydrochloride). [Revised in July 2020] [Accessed on June 30, 2021] https://ciplamed.com/print-product-pdf/37162

USEFUL DIAGNOSTIC TESTS

  • Glucose - Fasting Blood
  • Glucose - Postprandial Blood
  • Glycosylated Hemoglobin

PRODUCT DETAILS

    Net Qty
    1 N
    Shelf Life
    24 Months
    Hsn Code
    30049099
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