INTRODUCTION
VEXOR XR 75MG TABLET contains Venlafaxine which belongs to the group of medicines called Antidepressants. It is used in adults to treat depression, anxiety disorders and panic attacks (fear).
Depression is a mental health disorder characterized by persistant depressed mood, lack of interest, feeling of guilt, sleep disturbances or sucidial thoughts for a prolonged period (more than 2 weeks) that causes significant impairment in performing day-to-day activities.
Before taking VEXOR XR 75MG TABLET, inform your doctor if you have diabetes or any liver, kidney or heart problems. You must also inform your doctor if you have or have a family history of bipolar disorder, mania or epilepsy. Do not take VEXOR XR 75MG TABLET if you are pregnant or breastfeeding without consulting your doctor.
The most common side effects of taking VEXOR XR 75MG TABLET are headache, dizziness, drowsiness, lack of sleep, dry mouth and sexual problems. Consult your doctor if any of these side effects worsen.
USES OF VEXOR XR 75MG TABLET
It is used in adults to treat:
- Depression
- Anxiety disorders (both generalized and social-anxiety)
- Panic attacks (fear)
HOW VEXOR XR 75MG TABLET WORKS
VEXOR XR 75MG TABLET is a potent antidepressant drug. It contains a medicine called venlafaxine which is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It acts by increasing the levels of certain chemicals (serotonin and norepinephrine) within the brain that elevates your mood and stabilizes mental health. As a result, it makes you feel active and energetic and reduces unnecessary fear and anxiety.
DIRECTIONS FOR USE
Take VEXOR XR 75MG TABLET with food or as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine.
Your doctor will decide the correct dose and duration of theray for you depending upon your age, body weight and disease condition.
Do not stop taking VEXOR XR 75MG TABLET abruptly as it may lead to withdrawal symptoms such as aggressiveness, tiredness, dizziness, sleeplessness, nightmares, dry mouth, nervousness, agitation, confusion or ringing in the ears.
SIDE EFFECTS OF VEXOR XR 75MG TABLET
COMMON
- dizziness, headache, drowsiness
- insomnia (lack of sleep)
- nausea, vomiting, diarrhea, decreased appetite, constipation
- dry mouth
- sweating (including night sweats)
- confusion, agitation, nervousness, abnormal dreams
- lack of orgasm, decreased sex drive, problems in erection or sperm release
- tremor
- fast heartbeat, palpitations
- flushing of skin, skin rash, itching
- increased frequency of urination, inability to pass urine
- irregular periods
- increased bleeding tendency
- tiredness, weakness, chills
- weight gain, weight loss
- increased cholesterol levels
UNCOMMON
- overactivity, racing thoughts, and mania
- hallucinations
- loss of balance, involuntary movements of the muscles
- feeling dizzy (mainly when standing up too quickly)
RARE
Stop taking VEXOR XR 75MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reactions (such as skin rash, itching, swellling of the face, lips, tongue and throat which causes difficulty in breathing or swallowing)
- severe allergic skin reactions with blistering and peeling of skin
- signs of serotonin syndrome (feeling agitated, hallucinations, confusion, loss of consciousness, fast heartbeat, feeling dizzy, increased sweating, flushing, tremors, stiff muscles, or muscle twitching, loss of coordination, nausea, vomiting, diarrhea or seizures)
- signs of Neuroleptic Malignant Syndrome (such as fever, fast heartbeat, sweating, severe muscle stiffness, confusion, increased muscle enzymes)
- signs of infection, such as high temperature, chills, shivering, headaches, sweating, and flu-like symptoms (may be a sign of blood disorders)
- unexplained weakness, muscle pain, or tenderness (may be a sign of rhabdomyolysis)
- worsening of depression, suicidal thoughts or behavior
- increased signs of bleeding or bruising
- problems in vision (such as blurred vision, dilated pupils)
- black tarry or bloody stools
WARNING & PRECAUTIONS
PREGNANCY
VEXOR XR 75MG TABLET should be used in pregnant women only if considered necessary by the physician. Your doctor will evaluate the risks and benefits of the therapy and prescribes you with this medicine only if the benefits overweigh the risk to the growing baby. Therefore, consult your doctor before taking it.
BREASTFEEDING
VEXOR XR 75MG TABLET may pass through the breast milk. Therefore, it should be used in breastfeeding women only if considered necessary by the physician. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking VEXOR XR 75MG TABLET.
ALCOHOL
Avoid consumption of alcohol while taking VEXOR XR 75MG TABLET.
KIDNEY
VEXOR XR 75MG TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
LIVER
VEXOR XR 75MG TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not take VEXOR XR 75MG TABLET if you are allergic to Venlafaxine.
HEART DISEASE
VEXOR XR 75MG TABLET should be used with caution in patients with heart diseases (such as high blood pressure or abnormal heartbeat). Therefore, consult your doctor before taking it.
OTHERS
Before taking VEXOR XR 75MG TABLET, inform your doctor if you:
- have or ever had any bleeding problems
- have or have a family history of various mental illness (such as bipolar disorder, mania, and hypomania)
- have diabetes
- have ever felt extremely sad with suicidal thoughts or behaviour
- have or ever had seizures (fits)
- have low blood sodium levels (causing tiredness, confusion, and muscle weakness)
- have glaucoma
Use in pediatrics:
VEXOR XR 75MG TABLET is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before administration.
Use in geriatrics:
VEXOR XR 75MG TABLET should be used with caution in elderly patients. Therefore, consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions –
Before taking VEXOR XR 75MG TABLET, inform your doctor if you are taking any of the following medicines such as:
- other medicines used to treat depression such as monoamine oxidase inhibitors (Ex. moclobemide, isocarboxazid, phenelzine and tranylcypromine), tricyclic antidepressants (Ex. amitriptyline, nortriptyline), lithium, fluoxetine, sertraline, citalopram, escitalopram etc.
- buprenorphine (a medicine used for pain relief or opiod dependence)
- linezolid (an antibiotic used to treat bacterial infection)
- sibutramine (a medicine used for weight loss)
- intravenous methylene blue (used to treat abnormal methemoglobin levels in blood)
- medicines used to treat migraine headaches (such as sumatriptan, zolmitriptan)
- fentanyl (an opioid analgesic used for pain relief)
- tramadol (used for pain relief)
- tryptophan (an aminoacid used for maintaing mental health)
- amphetamines (used as CNS stimulants) Ex. dexamphetamine and lisdexamphetamine
- dextromethorphan (a cough medicine)
- methadone (a medicine used to treat pain or drug addiction)
- pentazocaine (an anesthetic used to cause numbness before surgeries)
- St. John’s Wort (a herbal medicine used to treat depression)
- medicines that can affect blood clotting (such as aspirin or warfarin)
- medicines used to treat psychotic disorders (Ex. chlorpromazine, prochlorperazine, trihexiphenidyl, haloperidol or risperidone)
- medicines used to treat heart problems (Ex. quinidine, amiodarone, sotalol, metoprolol or defatilide)
- medicines used to treat bacterial infections (Ex. erythromycin or moxifloxacin)
- antihistamines (used to treat allergies) Ex. fexofenadine, levocetirizine
- medicines used to treat fungal infection (Ex. ketoconazole)
Overdosage:
If you or anyone else accidentally consumed more VEXOR XR 75MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage might include fast heartbeat, sleepiness, blurred vision, fits and vomiting.
SYNOPSIS
| Drug | : | Venlafaxine |
| Pharmacological Category | : | Selective Serotonin and Norepinephrine Reuptake Inhibitors (SNRI) |
| Therapeutic Indication | : | Depression, Anxiety, Panic attacks |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep VEXOR XR 75MG TABLET out of reach of children
- Store VEXOR XR 75MG TABLET at room temperature
FAQs ABOUT VEXOR XR 75MG TABLET
What is the use of VEXOR XR 75MG TABLET?
VEXOR XR 75MG TABLET is an antidepressant medicine used to treat depression, anxiety disorders and panic attacks in adults.
How long does it take for VEXOR XR 75MG TABLET to work?
It may take several weeks for VEXOR XR 75MG TABLET to heal your condition. Therefore, continue to take VEXOR XR 75MG TABLET for the stipulated duration recommended by your doctor without any interruption.
Is VEXOR XR 75MG TABLET a strong antidepressant?
Yes. VEXOR XR 75MG TABLET is a strong antidepressant that effectively controls signs of depression, anxiety and fear. It works by increasing the levels of certain chemicals (serotonin and noreipherine) within the brain that stabilizes mental health.
What is the best time to take VEXOR XR 75MG TABLET?
Take VEXOR XR 75MG TABLET approximately at the same time each day. You can take VEXOR XR 75MG TABLET either in the morning or in the evening as per doctor’s instructions. Taking it at the same time each day will have the best effect and it would also help you remember your daily dose.
Can VEXOR XR 75MG TABLET be used to reduce anxiety?
Yes. VEXOR XR 75MG TABLET is an antidepressant medicine used to treat depression, anxiety disorders and panic attacks in adults.
How does VEXOR XR 75MG TABLET works?
VEXOR XR 75MG TABLET is a potent antidepressant drug. It acts by increasing the levels of certain chemicals (serotonin and norepinephrine) within the brain that elevates your mood and stabilizes mental health. As a result, it makes you feel active and energetic and reduces the signs of anxiety and fear.
Can I take VEXOR XR 75MG TABLET in the mornings?
Take VEXOR XR 75MG TABLET approximately at the same time each day. You can take VEXOR XR 75MG TABLET either in the morning or in the evening as per doctor’s instructions. Taking it at the same time each day will have the best effect and it would also help you remember your daily dose.
Can VEXOR XR 75MG TABLET cause weight gain?
Yes. Weight gain is one of the common side effects of taking VEXOR XR 75MG TABLET. If this side effect bothers you, contact your doctor.
Will VEXOR XR 75MG TABLET reduce my sex drive?
Yes. VEXOR XR 75MG TABLET may affect your sexual life. It may decrease sex drive or causing problems in orgasm, ejaculation or erection. Therefore, consult your doctor if you experience any such symptoms.
Will the use of VEXOR XR 75MG TABLET make you feel sleepy or tired?
Yes, VEXOR XR 75MG TABLET can make your feel sleepy, drowsy, or tired. Do not drive or handle heavy machines or tool if you feel drowsy or sleepy. Avoid consumption of alcohol as it can aggravate your drowsiness.
What precautions must be followed while taking VEXOR XR 75MG TABLET?
Before taking VEXOR XR 75MG TABLET, inform your doctor if you have diabetes, or any liver, kidney or heart problems. You must also inform your doctor if you have or have a family history of bipolar disorder, mania or epilepsy. Do not take VEXOR XR 75MG TABLET if you are pregnant or breastfeeding without consulting your doctor. Avoid taking other antidepressant medicines concomittantly while taking VEXOR XR 75MG TABLET without consulting your doctor. Take VEXOR XR 75MG TABLET for the stipulated duration recommended by your doctor to achieve better results. Contact your doctor immediately if you experience any worsening or depression, unusual behaviour or have suicidal thoughts or behaviour after taking VEXOR XR 75MG TABLET.
Can VEXOR XR 75MG TABLET be used in children?
VEXOR XR 75MG TABLET is generally not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before administration.
What to do if I forget to take a dose of VEXOR XR 75MG TABLET?
If you forget to take a dose of VEXOR XR 75MG TABLET, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of VEXOR XR 75MG TABLET to compensate a missed dose, as it could lead to toxicity.
Will taking a higher dose of VEXOR XR 75MG TABLET than the prescribed one be beneficial?
No, taking a higher dose of VEXOR XR 75MG TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Can I stop taking VEXOR XR 75MG TABLET once my symptoms subside?
No. Do not stop taking VEXOR XR 75MG TABLET without consulting your doctor even if you feel better during the mid-way of the therapy. You may feel better after 2 weeks of therapy with VEXOR XR 75MG TABLET, but it might take several weeks for you to experience complete benefits. Also, sudden discontinuation of therapy may cause withdrawal symptoms such as headache, dizziness, nausea, irritability, lack of sleep, diarrhea, anxiety, abnormal dreams, fatigue, and increased sweating.
Can VEXOR XR 75MG TABLET be taken daily?
Yes. VEXOR XR 75MG TABLET can be taken daily as per your doctor’s instruction. However, if you are doubtful, consult your doctor.
REFERENCES
1. KD. Tripathi. Antidepressants and Anti-anxiety Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 462.
2. Gavin J. Lyndon, Rita Prieto, Dalia B. Wajsbrot, Christer Allgulander and Borwin Bandelow. Efficacy of venlafaxine extended release in major depressive disorder patients: effect of baseline anxiety symptom severity. NIH. National Library of Medicine. National Center of Biotechnology Information. PMC PubMed Central. May 2019. [Accessed on 26th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445597/
3. Aspire Pharma Ltd. Electronic Medicines Compendium (EMC). [Revised in March 2022]. [Accessed on 26th November 2022] https://www.medicines.org.uk/emc/files/pil.2686.pdf
4. Cipla Ltd. Venlor XR Capsules (Venlafaxine Hydrochloride). Ciplamed.com. [Revised in February 2018]. [Accessed on 26th November 2022] https://www.ciplamed.com/content/venlor-xr-capsules
5. Central Drugs Standard Control Organization. Venlafaxine hcl. September 2000. [Accessed on 26th November 2022] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalNewDrugs/1991_2000new.pdf
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