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Vertigil 10mg/20mg Tablet 6'S

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Migraine Rx required
Cinnarizine 20 mg+Domperidone 10 mg
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₹34.65 MRP ₹49.50 Save 30 %
Inclusive of all taxes
*6 Tablet(s) in a Strip * Mkt: Cipla Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

INTRODUCTION

VERTIGIL 10MG/20MG TABLET is a combination of Cinnarizine and Domperidone which belongs to the group of medicines called Anti histamines and Anti-emetic agents. It is used to treat vertigo or meniere’s disease, nausea and vomiting due to motion sickness. It is also used for the management of vestibular disorders.

Cinnarizine is an antihistaminic and blocks the calcium channels, inhibiting smooth muscle contraction and improves microcirculation to inner ear and relieves vertigo or spinning sensation. Domperidone is a prokinetic agent that works on the upper digestive tract and increase the movement of food through stomach and intestine more quickly. It also works by blocking dopamine (a chemical which is responsible for feeling of nausea or vomiting) in the brain. Therefore, relieving vertigo associated with nausea and vomiting

Before taking VERTIGIL 10MG/20MG TABLET inform your doctor if you have liver, kidney or heart disease. VERTIGIL 10MG/20MG TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Contact your doctor before taking it. VERTIGIL 10MG/20MG TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it. VERTIGIL 10MG/20MG TABLET is not recommended for use in children. Contact your doctor before taking. VERTIGIL 10MG/20MG TABLET should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before taking. The most common side effects of this medicine are nausea, dryness in mouth, Indigestion, Sleepiness, and, Weight gain. Contact your doctor if any of the symptoms worsen.

USES OF VERTIGIL 10MG/20MG TABLET

Treats:

  • vertigo or meniere’s disease,
  • motion sickness,
  • vestibular disorders

HOW VERTIGIL 10MG/20MG TABLET WORKS

VERTIGIL 10MG/20MG TABLET helps to relieve vertigo associated with nausea and vomiting, where Cinnarizine works by blocking the calcium channels, inhibiting smooth muscle contraction and improves microcirculation to inner ear and domperidone is a prokinetic agent that works on the upper digestive tract and increase the movement of food through stomach and intestine more quickly. It also works by blocking dopamine (a chemical which is responsible for feeling of nausea or vomiting) in the brain.

DIRECTIONS FOR USE

Take this medicine as advised by your physician. Swallow this medicine as whole with a glass of water and do not crush or chew the medicine.

SIDE EFFECTS OF VERTIGIL 10MG/20MG TABLET

COMMON

  • nausea, dryness in mouth, Indigestion,
  • sleepiness, drowsiness
  • weight gain

UNCOMMON

  • excessive sweating
  • red or pinkish skin with patches of spots and a crust
  • vomiting
  • decreased sexual drive (libido) in men
  • anxiety
  • diarrhea
  • headache
  • itchy skin
  • unusual production of breast milk in men and women
  • painful or tender breasts
  • feeling weak

RARE

  • stomach upset
  • galactorrhea or menstrual irregularities.
  • gynecomastia (breast enlargement in men)

Stop taking VERTIGIL 10MG/20MG TABLET and contact your doctor immediately if you experience any of the following side effects:

  • allergic reactions such as a red, itchy rash, hives or swelling of the face, lips, tongue or throat, difficulty breathing

HOW TO MANAGE SIDE EFFECTS

Indigestion

Eat smaller meals but take frequently. Eat and exercise regularly. Contact your doctor if the symptom does not improve.

Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

WARNING & PRECAUTIONS

PREGNANCY
Monitoring required

VERTIGIL 10MG/20MG TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Contact your doctor before taking.

BREASTFEEDING
Contraindicated

VERTIGIL 10MG/20MG TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.

DRIVING AND USING MACHINES
Use with Caution

Do not drive or operate machinery if you feel drowsy or sleepiness after taking VERTIGIL 10MG/20MG TABLET.

ALCOHOL
Consult your doctor

Avoid consumption of alcohol while taking VERTIGIL 10MG/20MG TABLET because it might make you drowsy.

KIDNEY
Use with Caution

VERTIGIL 10MG/20MG TABLET should be used with caution in patients with kidney disease. Contact your doctor before taking

LIVER
Contraindicated

VERTIGIL 10MG/20MG TABLET is not recommended for use in patients with moderate to severe liver disease. Contact your doctor before taking.

ALLERGY
Contraindicated

Do not take VERTIGIL 10MG/20MG TABLET if you are allergic to cinnarizine, domperidone, or to other ingredients of this medicine.

HEART DISEASE
Contraindicated

VERTIGIL 10MG/20MG TABLET is not recommended for use in patients with heart diseases such as heart failure, heart rhythm disorders like prolonged QT interval. Contact your doctor before taking.

OTHERS

VERTIGIL 10MG/20MG TABLET is not recommended for use if you have:

  • bleeding in the stomach or intestines symptoms such as black, tarry bowel stools or notice blood in your bowel motions.
  • blockage or tear in intestines
  • tumour of the pituitary gland (prolactinomas)
  • low level of potassium or magnesium, or high level of potassium in blood
  • Parkinson’s disease.
  • GI haemorrhage, obstruction and perforation,
  • excess prolactin releasing pituitary hormone
  • for chronic administration or prophylaxis of post-operative nausea and vomiting

Before taking VERTIGIL 10MG/20MG TABLET, inform your doctor if you have:

  • hypotension,
  • pheochromocytoma,
  • hypokalaemia

Use in pediatrics:

VERTIGIL 10MG/20MG TABLET is not recommended for use in children. Consult your doctor before taking.

Use in geriatrics:

VERTIGIL 10MG/20MG TABLET should be used with caution in elderly patients (aged 65 years or above). Contact your doctor before taking.

INTERACTIONS

A. Drug-Drug interactions:

Inform your physician, if you are using,

  • digoxin (medicine used for heart failure)
  • aspirin (medicine used to treat blood clots)
  • paracetamol (medicine used to treat fever)
  • diazepam (medicine used to treat anxiety)
  • phenothiazines (medicines used to treat psychotic disorders)
  • antimuscarinic agents Ex. atropine, hyoscamine (medicine used to treat overactive bladder syndrome, bradycardia etc.)
  • opiods  Ex. codeine (medicine used for severe pain)
  • suxamethonium (medicine used in anaesthesia)
  • medicines used to treat psychoses (haloperidol, pimozide, sertindole)
  • citalopram, escitalopram (medicines used for depression)

Overdosage: If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of Overdosage include nausea, stomach upset, drowsiness or sleepiness, unusual eye movements, tongue or uncontrollable muscle spasms, weakness, prolonged QT interval and seizures in young children.

 
 

SYNOPSIS

Drug :   Cinnarizine, Domperidone
Pharmacological Category :   Antihistamics, Antiemetics
Therapeutic Indication :   vertigo or meniere’s disease, motion sickness, vestibular disorders
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep out of reach of children
  • Store at room temperature

FAQs ABOUT VERTIGIL 10MG/20MG TABLET

Does VERTIGIL 10MG/20MG TABLET cause drowsiness?

Yes. VERTIGIL 10MG/20MG TABLET cause drowsiness or sleepiness. Try to rest and relax. Get enough sleep. Avoid driving or operating any machines while you are feeling dizzy. Avoid consumption of alcohol as it can aggravate your dizziness. Contact your doctor if the symptom persists for longer time.

For what conditions VERTIGIL 10MG/20MG TABLET is used?

VERTIGIL 10MG/20MG TABLET is used to treat vertigo or meniere’s disease, nausea and vomiting due to motion sickness. It is also used for the management of vestibular disorders. Contact your doctor before taking.

How VERTIGIL 10MG/20MG TABLET works?          

VERTIGIL 10MG/20MG TABLET helps to relieve vertigo associated with nausea and vomiting, where Cinnarizine works by blocking the calcium channels, inhibiting smooth muscle contraction and improves microcirculation to inner ear and domperidone is a prokinetic agent that works on the upper digestive tract and increase the movement of food through stomach and intestine more quickly. It also works by blocking dopamine (a chemical which is responsible for feeling of nausea or vomiting) in the brain.

What are the possible side effects of taking VERTIGIL 10MG/20MG TABLET?

The most common side effects of this medicine are nausea, dryness in mouth, Indigestion, Sleepiness, and, Weight gain. Contact your doctor if any of the symptoms worsen.

Can I use VERTIGIL 10MG/20MG TABLET in pregnancy?

No. VERTIGIL 10MG/20MG TABLET is generally not recommended for use in pregnant women unless considered clearly necessary. Contact your doctor before taking.

REFERENCES

1. K.D.Tripathi. Autocoids and related drugs, Antiemetic, prokinetic and digestant drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page- 168,663, 666

2. Tanvi S. Tambawala, Pranav J. Shah, Shailesh A. Shah. Uses of Cinnarizine and domperidone. International Journal of Pharmaceutical Sciences and Technology and Management. 2015. [Accessed on 1st June 2022] https://pharmacy.nmims.edu/docs/orally-disintegrating-article-09.pdf

3. Milind Vasant Kirtane, Anita Bhandari, Prashant Narang, Ravi Santani. Mechanism of cinnarizine: A contemporaray review. Indian Journal of otolaryngology and Head and Neck Surgery. April 2017. [Accessed on 1st June  2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841794/#:~:text=Mechanism%20of%20Action,Cinnarizine%2C%20developed%20as&text=Cinnarizine%20inhibits%20smooth%20muscle%20cell,dopamine%20D2%20receptors%20%5B6%5D.

4. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised on January 2021] [Accessed on 1st June 2022] https://www.medicines.org.uk/emc/files/pil.2607.pdf

5. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised on March 2021] [Accessed on 1st June 2022] https://www.medicines.org.uk/emc/files/pil.556.pdf

6. Cinnarizine and Domperidone. Mims.com. [Accessed on 1st June 2022] https://www.mims.com/india/drug/info/cinnarizine%20+%20domperidone?type=full&mtype=generic

7. Cinnarizine and Domperidone. Leeford healthcare. [Accessed on 1st June 2022] https://www.leeford.in/product/802/sinadom

8. Cinnarizine and Domperidone. Vibcare. [Accessed on 1st June 2022] https://vibcare.co.in/cinnarizine-domperidone/

9. Cinnarizine and Domperidone. Somacare.co.in. [Accessed on 1st June 2022] https://www.somacare.co.in/product/domperidone-10mg-cinnarizine-25mg

10. Cinnarizine and Domperidone. Neuraclelife. [Accessed on 1st June 2022] https://www.neuraclelife.com/product/cinnarizine-domperidone-tablet/

11. Cinnarizine and Domperidone. DM pharma. [Accessed on 1st June 2022] https://dmpharma.co.in/Cinnarizine%20and%20Domperidone%20Tablet.html

AUTHOR DETAILS

Written By Dr. Dhivakaran R, BDS
Last updated on 30 Jan 2023 | 03:57 PM(IST)

PRODUCT DETAILS
    Net Qty
    1 N
    Shelf Life
    24
    Item Weight
    15 g
    Ingredient
    Cinnarizine 20 mg+Domperidone 10 mg
    Hsn Code
    30049099
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