INTRODUCTION

VENDEP D 100MG contain desvenlafaxine which belongs to a group of medicine called SNRIs (serotonin-norepinephrine reuptake inhibitors). It is used to treat depression. This medicine works by increasing the levels of chemical messengers such as serotonin and noradrenaline in the brain that help maintain mental balance.

Always take VENDEP D 100MG exactly as your doctor has told you. This medicine must be taken with or without food. It should be swallowed whole with water. Do not crush or chew the medicine. This medicine is strictly not recommended for use in children and adolescents. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine. The most common side effects are nausea, vomiting, sweating, dizziness, insomnia, constipation, diarrhoea, loss of appetite, anxiety, decreased sex drive, delayed orgasm, and ejaculation.

USES OF VENDEP D 100MG

• Treat depression

HOW VENDEP D 100MG WORKS

VENDEP D 100MG works by increasing the levels of chemical messengers such as serotonin and noradrenaline, natural substances in the brain that help maintain mental balance.

DIRECTIONS FOR USE

Always take VENDEP D 100MG exactly as your doctor has told you. It must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF VENDEP D 100MG

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Dry mouth:

Chew sugar-free gum or suck on sugar-free hard candies. Control your caffeine intake. Do not use mouthwashes. Sip water regularly.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.  

Constipation: 

Eat fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Diarrhoea:

Drink lot of fluids such as water or squash, to avoid dehydration. Do not take any other medicines without talking to a doctor.

Sleepiness:

Get up and move around to feel awake. Take a nap to take the edge off the sleepiness. Give your eyes a break to avoid weakness.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking,

• triptans (used to treat migraine headaches)
• tricyclics, lithium, selective serotonin reuptake inhibitor (SSRIs), serotonin norepinephrine reuptake inhibitor (SNRIs), antipsychotic drugs, or other dopamine antagonists, such as metoclopramide (used to treat mood, anxiety, psychotic, or thought disorders)
• silbutramine
• tramadol
• St. John’s Wort
• MAOIs (including linezolid, an antibiotic)
• tryptophan supplements
• other medicines containing venlafaxine

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT VENDEP D 100MG

Will VENDEP D 100MG affect my sex drive?

This medicine may cause a decrease in sexual desire and ability. It may also cause delay in orgasm and ejaculation and sometimes ejaculation failure. Discuss with your doctor if you experience any of these symptoms while taking this medicine.

Can VENDEP D 100MG cause Constipation?

Yes, this medicine may cause constipation in some individuals. Eat fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Is VENDEP D 100MG good for anxiety?

It has been shown to be effective in relieving symptoms of anxiety, though it is not approved for anxiety. It is used in anxiety disorders only when advised by the doctor.

REFERENCES

1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page – 1088-1092.

2. Daniel Z Lieberman and Suena H Massey. Desvenlafaxine in major depressive disorder: an evidence-based review of its place in therapy. US National Library of Medicines, National Institutes of Health. 15 Jun 2010. [Accessed 01 Dec 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2899788/

3. Wyeth pharmaceuticals Inc,2008; U.S. Food & Drug Administration; [Revised on Oct 2011] [Accessed 01 Dec 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021992s030lbl.pdf