VAPAL 150mg Tablet 1's

INTRODUCTION

VAPAL 150MG contain levamisole which belongs to a group of medicine called immune-modulating agents. It is used to treat Steroid Sensitive Nephrotic Syndrome (SSNS). It is used during and following a therapy with prednisone or prednisolone.

Steroid Sensitive Nephrotic Syndrome is a rare primary glomerulopathy of unknown cause characterized by edema, nephrotic-range proteinuria and hypoalbuminemia that responds to standard prednisone treatment within 4-6 weeks.

The common side effects are nervousness, sleepiness, depression, nausea, vomiting, reduced appetite, diarrhoea, constipation, inflammation of the pancreas (pancreatitis) (symptoms such as stomach pain), skin rash and inflammation, malformations of the skin such as red swollen spots, muscle and joint pain, inflammation of the mouth, change to your odour.

VAPAL 150MG works by restoring depressed immune function rather than to stimulate response to above-normal levels. This medicine can be taken with some water or, if necessary, with custard or any appropriate liquid.

Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.

USES OF VAPAL 150MG

• Treat Steroid Sensitive Nephrotic Syndrome (SSNS)

HOW VAPAL 150MG WORKS

VAPAL 150MG works by restoring depressed immune function rather than to stimulate response to above-normal levels.

DIRECTIONS FOR USE

Always take VAPAL 150MG exactly as your doctor has told you. VAPAL 150MG can be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.

SIDE EFFECTS OF VAPAL 150MG

HOW TO MANAGE SIDE EFFECTS

Sleepiness:

Get up and move around to feel awake. Take a nap to take the edge off the sleepiness. Give your eyes a break to avoid weakness.

Nausea and vomiting:

Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Diarrhoea:

Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without talking to a doctor.

Constipation: 

Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Applying heat pad or covered hot water bottle on your stomach. If still pain persists, speak to your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor if you are taking,

• anticoagulants (blood-thinners)
• phenytoin (used for epilepsy)
• other medicines that effect the formation of blood cells (hematopoiese)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT VAPAL 150MG

Is VAPAL 150MG effective?

Yes, it is effective if used in the dose and duration as advised by your doctor.

Can VAPAL 150MG cause constipation?

Yes, this medicine may cause constipation in some individuals. Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Can I take VAPAL 150MG during pregnancy?

No, it is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

REFERENCES

1. KD Tripathi. Anthelmintic Drugs. Essentials of Medical Pharmacology. Seventh Edition, 2013. Page - 852-853.

2. Lulu Jiang 1, Ishita Dasgupta 1, Jenny A Hurcombe 1, Heather F Colyer 1, Peter W Mathieson 1, Gavin I Welsh 1. Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. Jun 2015. [Accessed 23 Jan 2021] https://pubmed.ncbi.nlm.nih.gov/25626449/

3. TAJ PHARMACEUTICALS Ltd; Electronic Medicines Compendium (EMC); [Revised on Aug 2015] [Accessed 23 Jan 2021] https://tajpharmaindia.com/wp-content/uploads/2015/09/PIL-FINITOR-LEVAMISOLE-HCL-TAB.pdf