INTRODUCTION

VANOGARD 1000MG contains Vancomycin which belongs to a group of medicines called glycopeptide antibiotics. It is used to treat severe infections caused by susceptible strains of methicillin-resistant (betalactam-resistant) staphylococci and staphylococcal endocarditis.

Vancomycin is a tricyclic glycopeptide antibiotic which inhibits the synthesis of the cell wall in sensitive bacteria by binding with high affinity to the D-alanyl-D-alanine terminus of cell wall precursor units. The bactericidal action of vancomycin against Staphylococcus aureus and the vegetative cells of Clostridium difficile results primarily from the inhibition of cell wall biosynthesis and alters the bacterial cell membrane permeability and RNA synthesis.

Before receiving VANOGARD 1000MG inform your doctor if you have liver, kidney or heart problems, are pregnant or breastfeeding. Your physician will administer the right dose depends on your child’s age and body weight. The common side effects are inflammation at the injection site, decrease in blood pressure, breathlessness and laboured breathing.

USES OF VANOGARD 1000MG

• Treats severe infections caused by susceptible strains of methicillin-resistant (betalactam-resistant) staphylococci and staphylococcal endocarditis

HOW VANOGARD 1000MG WORKS

Vancomycin which belongs to a class of medications called glycopeptide antibiotics which work by killing the bacteria in the intestines.

DIRECTIONS FOR USE

VANOGARD 1000MG will be administered by your doctor or nurse by intravenously.

SIDE EFFECTS OF VANOGARD 1000MG

HOW TO MANAGE SIDE EFFECTS

Nausea:

Take normal regular meals and do not eat spicy foods.

Dizziness:

Get up and move around to feel awake and eat a healthy food to boost your energy.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking,

• anti-motility agents
• ototoxic and/or nephrotoxic drug
• teicoplanin, aminoglycosides, streptomycin, neomycin, gentamicin, kanamycin, amikacin, bacitracin, tobramycin, polymyxin B, colistin (treats infection)
• amphotericin B (treats fungal infections)
• ciclosporin (suppress the activity of the immune system)
• diuretic medicines (loop diuretics)
• anaesthetics
• muscle relaxants
• oral contraceptives

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT VANOGARD 1000MG

Can I stop taking VANOGARD 1000MG when my symptoms are relieved?

No, do not stop taking and complete the full course of treatment even if you feel better.

How long does VANOGARD 1000MG take to work?

It starts working soon after taking it. But it may take some days to kill all the harmful bacteria.

How is VANOGARD 1000MG given?

It will be administered intravenously by your doctor or nurse.

REFERENCES

1. KD Tripathi MD. Beta-lactam antibiotics. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 721.

2. MacDougall C, Chambers HF. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 539-542.

3. Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page - 786-787.

4. Will A. McGuinness, Natalia Malachowa, and Frank R. DeLeo. Vancomycin Resistance in Staphylococcus aureus. June 23, 2017.  [Accessed on June 23, 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482303/

5. Biocon Limited. Neon Laboratories Limited. [Accessed on June 23, 2021] https://www.biocon.com/docs/prescribing_information/ccd/vancowarcp_pi.pdf

6. Vancomycin Hospira. [Accessed on June 23, 2021] https://mri.cts-mrp.eu/Human/Downloads/AT_H_0551_001_FinalPL.pdf

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count