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INTRODUCTION
UVOX 100MG contains Fluvoxamine which belongs to a group of medicines called selective serotonin re-uptake inhibitors (SSRI). It is used to treat depression (major depressive episode). It can also treat people who have obsessive compulsive disorder (OCD). Obsessive compulsive disorder is characterized by recurrent and persistent thoughts, impulses or images (obsessions) that are repetitive and other intentional behaviors that are recognized as excessive or unreasonable.
Fluvoxamine works by inhibiting the uptake of serotonin, a neurotransmitter, from the spaces between nerve cells following its release. Therefore, there is more serotonin available in the spaces to attach to other nerves and stimulate them. Always take UVOX 100MG exactly as prescribed by your doctor. Do not chew or crush this medicine. Swallow the medicine whole. It is not recommended for use in the children under 18 years of age. Consult your doctor for advice if you experiance any changes in mood, behaviors, thoughts, or feelings during this medication.
THERAPEUTIC USES OF UVOX 100MG
- Depression (major depressive episode)
- Obsessive compulsive disorder (OCD)
HOW UVOX 100MG WORKS
Selective serotonin reuptake inhibitors affect the neurotransmitters, the chemicals that nerves in the brain used to communicate with each other. Neurotransmitters are released by nerves, travel across the spaces between them and then attach to receptors on other nerves. This medicine works by inhibiting the uptake of serotonin, a neurotransmitter, from the spaces between nerve cells following its release. Therefore, there is more serotonin available in the spaces to attach to other nerves and stimulate them which helps to alter and lighten the mood.
DIRECTIONS FOR USE
Always take UVOX 100MG exactly as prescribed by your doctor. Do not chew or crush this medicine. Swallow the medicine as a whole.
SIDE EFFECTS OF UVOX 100MG
SERIOUS
- Serotonin syndrome - sweating, muscle stiffness or spasms, instability, confusion, irritability or extreme agitation
- Neuroleptic malignant syndrome - stiff muscles, high temperature, confusion and other related symptoms
- feeling tired, weak or confused and have achy, stiff or uncontrolled muscles
COMMON
- headache
- diarrhea, nausea, vomiting
- dizziness
- agitation, anxiety
- constipation
- difficulty sleeping
- dry mouth
- faster heartbeat
- feeling drowsy (lethargy)
- indigestion
- loss of appetite
- nervousness, tremor, muscle weakness (asthenia)
- stomach pain
- sweating
RARE
- convulsions
- liver complaints
- mania (a feeling of elation or over-excitement)
- sensitivity to sunlight
HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Headache:
Rest and drink plenty of fluids. Apply a cold, wet cloth or ice pack to your forehead. Rest in a quiet, comfortable, dark room.
Stomach pain:
Try to rest and relax. You can eat and drink slowly or have frequent meals. Keeping a heat pad or a covered hot water pack on your stomach may also help. If still pain persists, speak to your doctor.
Constipation:
Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Excercise more regularly.
WARNING & PRECAUTIONS
PREGNANCY
UVOX 100MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
UVOX 100MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel sleepy while taking this medicine.
ALCOHOL
Consumption of alcohol is not recommended during treatment with this medicine.
KIDNEY
This medicine should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
This medicine should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
If you are allergic (hypersensitive) to this medicine or any other ingredients in this medicine.
HEART DISEASE
This medicine should be taken with caution in patients with heart disease. Consult your doctor for advice.
INTERACTIONS
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:
- aspirin (acetylsalicylic acid) or aspirin-like medicines, used to treat pain and inflammation (arthritis)
- ciclosporin, used to reduce the activity of the immune system
- methadone, used to treat pain and withdrawal symptoms
- mexiletine, used to treat abnormal heart rhythms
- phenytoin or carbamazepine, used to treat epilepsy
- propranolol, used to treat high blood pressure and heart conditions
- ropinirole, for Parkinson’s disease
- other medicine used for depression
- medicines used to treat migraine
- terfenadine, used to treat allergies
SYNOPSIS
| Drug | : | Fluvoxamine |
| Pharmacological Category | : | Selective Serotonin Reuptake Inhibitor |
| Therapeutic Indication | : | Depression |
| Dosage Forms | : | Tablet |
MORE INFORMATION
Store this medicine at room temperature and keep it out of reach of children.
REFERENCES
1. Jane Irons; Fluvoxamine in the treatment of anxiety disorders; [Revised on 2005] [Accessed 01 Oct 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424117/
2. K.D.Tripathi, Essentials of medical pharmacology, Drugs acting on central nervous system, Chapter 33 – Drugs Used in Mental Illness: Antidepressant and Antianxiety Drugs, Page – 454, 458, 461.
3. Mylan Products Ltd, Electronic Medicines Compendium (EMC); [Revised on 07/2019] [Accessed 01 Oct 2020] https://www.medicines.org.uk/emc/files/pil.1169.pdf
4. CP Pharmaceuticals Limited; Electronic Medicines Compendium (EMC); [Revised on 08/2019] [Accessed 01 Oct 2020] https://www.medicines.org.uk/emc/files/pil.2395.pdf
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