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MRP ₹197.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Modi Mundi Pharma Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

UNICONTIN E 400MG contains Theophylline which belongs to a group of medications called bronchodilators. It is used to treat asthma, long-term breathing difficulties such as chronic obstructive pulmonary disease and chronic bronchitis. Theophylline reduces swelling in the lungs of asthma patients and relieves the feeling of tightness in their chest. It relaxes the smooth muscle of bronchial airways and pulmonary blood vessels to relieve bronchospasm and increase flow rates and vital capacity. It also suppresses the response of airways to other stimuli like histamine, methacholine, adenosine and allergen.

Theophylline is contraindicated in patients with peptic ulcer, porphyria (a rare disease of blood pigments) and coronary artery disease. Always take this medicine as directed by your physician. Your doctor will decide the dose and duration of therapy depending upon your age, weight and condition. The most common side effects of taking this medicine are nausea, vomiting, headache and stomach upset. Avoid smoking and alcohol consumption while taking this medicine. If you are pregnant or breastfeeding do not take this medicine. Ask your doctor for advice. This medicine is not recommended for use in children under 6 years of age.

USES OF UNICONTIN E 400MG

  • Symptomatic treatment of reversible bronchospasm associated with asthma, chronic bronchitis, emphysema and related bronchospastic disorders

HOW UNICONTIN E 400MG WORKS

Theophylline relaxes the smooth muscle of bronchial airways and pulmonary blood vessels and reduces airway responsiveness to allergic substances like histamine, methacholine or adenosine. It also competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation.

DIRECTIONS FOR USE

Always take this medicine as directed by your physician. Your doctor will decide the dose and duration of therapy depending upon your age, weight and condition. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine.

SIDE EFFECTS OF UNICONTIN E 400MG

COMMON

  • nausea or vomiting
  • headache
  • diarrhea
  • stomach pain, heartburn, upset stomach
  • difficulty in sleeping
  • increased heartbeat
  • dizziness
  • difficulty in passing urine (especially in men)
  • seizures (fits)

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after, a meal. Stick to simple meals. Do not eat rich or spicy food.

Diarrhea:

Drink lots of fluids, such as water or squash, to avoid dehydration. Do not take any other medicines without speaking to a doctor.

Headache:  

Rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

WARNING & PRECAUTIONS

PREGNANCY

UNICONTIN E 400MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

UNICONTIN E 400MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or use any tools or machines if your ability is affected by this medicine.

ALCOHOL

Avoid consumption of alcohol while taking this medicine, because it can alter its activity.

KIDNEY

UNICONTIN E 400MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

LIVER

UNICONTIN E 400MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to theophylline or other xanthine derivatives.

HEART DISEASE

UNICONTIN E 400MG should be taken with caution in patients with high blood pressure or any other heart problems. Consult your doctor for advice.

OTHERS

Before taking this medicine, inform your doctor if you:

  • have an over-active thyroid gland, fever, viral infection, porphyria (a rare disease of the blood pigments) or are male and have difficulty in passing urine

INTERACTIONS

Talk to your doctor, if you are taking:

  • other medicines used to treat asthma or breathing conditions (e.g. aminophylline, salbutamol, terbutaline or salmeterol)
  • medicines used to treat cancer (e.g. aminoglutethimide, methotrexate or lomustine)
  • medicines used to treat epilepsy (carbamazepine or phenytoin)
  • medicines used to reduce anxiety (e.g. barbiturates, diazepam, flurazepam, lorazepam or midazolam)
  • medicines used to treat high blood pressure (e.g. adenosine, moracizine, diltiazem, isoprenaline, mexiletine, propafenone, verapamil or propranolol)
  • medicines used to treat gout (e.g. allopurinol, sulfinpyrazone)
  • medicines used to treat stomach ulcers (e.g. cimetidine or nizatidine)
  • carbimazole (used to treat problems with thyroid gland)
  • rifampicin or isoniazid (used to treat tuberculosis)
  • ritonavir (used to treat HIV)
  • thiabendazole (used to treat worms such as threadworms)
  • doxapram (used to stimulate breathing)
  • pentoxifylline (used to treat muscle pain)
  • ephedrine (a CNS stimulant)

SYNOPSIS

Drug :   Theophylline
Pharmacological Category :   Phosphodiesterase Enzyme Inhibitor
Therapeutic Indication :   Chronic asthma, other chronic lung diseases
Dosage Forms :   Tablet, Capsule, Injection

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT UNICONTIN E 400MG

Can UNICONTIN E 400MG be given to children?

It is not recommended for use in children under 6 years of age. Consult your doctor before taking.

Is UNICONTIN E 400MG habit-forming?

No. This medicine is not habit-forming.

REFERENCES

1. KD. Tripathi. Respiratory system drugs. Drugs for Cough and Bronchial asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 224-227.

2. Peter J. Barnes. Pulmonary pharmacology. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page – 1040-1043.

3. Gerald G. Briggs and Roger K. Freeman. T. A reference guide to fetal and neonatal risk: Drugs in Pregnancy and Lactation. Tenth Edition. 2015. Page – 3769-3772.

4. The First Affiliated Hospital of Guangzhou Medical University. The Effect of Theophylline in the Treatment of Bronchiectasis. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on March 2015] [Accessed 23rd November 2020] https://clinicaltrials.gov/ct2/show/NCT01684683

5. Zhujiang Hospital. Drug Interaction Study of Azithromycin and Theophylline. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on August 2014] [Accessed 23rd November 2020] https://clinicaltrials.gov/ct2/show/NCT02023554

6. R. Dhand, S. K. Malik, S.K. Grag, J. K. Bhutani, S. Swaminathan. Clinical trial of a sustained release theophylline tablet in adult asthmatics. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. October-November 1986. [Accessed 23rd November 2020] https://pubmed.ncbi.nlm.nih.gov/3301644/

7. Bard Pharmaceutical limited. Electronic Medicines Compendium (EMC); [Revised on October 2013] [Accessed 23rd November 2020] https://www.medicines.org.uk/emc/files/pil.1021.pdf

8. Merck Senero limited. Electronic Medicines Compendium (EMC); [Revised on April 2018] [Accessed 23rd November 2020] https://www.medicines.org.uk/emc/files/pil.7761.pdf

USEFUL DIAGNOSTIC TESTS

  • Absolute Eosinophil Count
  • Complete Blood Count

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    17.5
    Ingredient
    THEOPHYLLINE ANHYDROUS CONTROLLED RELEASE 400MG
    Hsn Code
    30049094
DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Unicontin E 400mg Tablet 10'S

Unicontin E 400mg Tablet 10'S Mkt: Modi Mundi Pharma Ltd

M.R.P.: Rs.197.00
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