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INTRODUCTION
TRIZ contain Cetirizine which belongs to a group of medicine called antihistamines. It is used to relieve the symptoms of hay fever (seasonal rhinitis) such as sneezing, itchy, red and watering eyes, irritated, runny or blocked nose in adults and children over the age of 2 years and also used to relieve the symptoms of other allergies such as runny and itchy nose (non-seasonal rhinitis), skin allergies such as rash, itching and urticaria (hives), pet or house mite allergies in adult and older children (over the age of 6 years).
TRIZ works by blocking the effects of histamine, which may be overproduced in allergic reactions which causes unpleasant symptoms such as itchy or watery eyes, running or blocked nose, sneezing and skin rashes. This medicine is strictly not recommended for use in children under 2 years. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
USES OF TRIZ
- Relieve the symptoms of hay fever, non-seasonal rhinitis, skin allergies such as rash, itching and urticaria (hives), pet or house mite allergies
HOW TRIZ WORKS
TRIZ works by blocking the effects of histamine, which may be overproduced in allergic reactions which causes unpleasant symptoms such as itchy or watery eyes, running or blocked nose, sneezing and skin rashes.
DIRECTIONS FOR USE
Always use TRIZ exactly as your doctor has told you. Check the label for directions before use. Shake well before use.
SIDE EFFECTS OF TRIZ
SERIOUS
- allergic reaction including severe reaction and angioedema (serious allergic reaction which cause swelling of the face or throat)
COMMON
- somnolence (sleepiness)
- diarrhoea, nausea, dry mouth
- fatigue
- pharyngitis, rhinitis (in children)
- dizziness, headache
RARE
- convulsions
- liver function abnormal
- oedema (swelling)
- depression, hallucination, aggression, confusion, insomnia
- tachycardia
- urticaria (hives)
- increase in weight
HOW TO MANAGE SIDE EFFECTS
Diarrhoea:
Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without talking to a doctor.
Nausea:
Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
WARNING & PRECAUTIONS
PREGNANCY
TRIZ is considered safe for use by pregnant women. It is advised to consult your doctor before taking this medicine.
BREASTFEEDING
TRIZ is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate machinery until you know how it affect you.
ALCOHOL
Consumption of alcohol is not recommended during treatment with TRIZ.
KIDNEY
TRIZ is not recommended in patients with active kidney diseases. Before taking this medicine consult your doctor. Consult your doctor for advice.
ALLERGY
Do not take TRIZ if you are allergic (hypersensitive) to cetirizine or any other ingredients in this medicine.
OTHERS
Tell your doctor if you have or had a condition such as,
- have problem passing urine (like spinal cord problems or prostate or bladder problem)
- suffer from epilepsy or are at risk of convulsion
- have hereditary intolerance to some sugars
- are due to have an allergy test, as this medicine may affect your allergy test results
INTERACTIONS
Talk to your doctor if you are taking,
- theophylline (used for some heart conditions or breathing disorders like asthma or bronchitis)
- central nervous system depressants such as barbiturates (used as sedatives or anaesthetics)
SYNOPSIS
| Drug | : | Cetirizine |
| Pharmacological Category | : | Antihistamines |
| Therapeutic Indication | : | Hay fever and allergic reactions |
| Dosage Forms | : | Tablet, Capsule, Syrup |
MORE INFORMATION
Store below 20-25°C and keep out of reach of children.
FAQs ABOUT TRIZ
Is TRIZ good for dry cough?
Yes, it improves cough due to pollen allergy. Antihistamines are more effective in reducing chronic cough in children with allergies.
Can I take TRIZ during pregnancy?
Yes, it is considered safe for use by pregnant women. It is advised to consult your doctor before taking.
Can TRIZ lower immune system?
No, this medicine does not influence the immune response.
REFERENCES
1. KD Tripathi. Histamine and Antihistaminics. Essentials of Medical Pharmacology. Seventh Edition,2013. Page-166-167.
2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page-708-711.
3. Monique P Curran 1, Lesley J Scott, Caroline M Perry. Cetirizine: a review of its use in allergic disorders. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov.2004. [Accessed 26 Dec 2020] https://pubmed.ncbi.nlm.nih.gov/14977391/
4. Pinewood Laboratories Ltd, Sep 2018; Electronic Medicines Compendium (EMC); [Accessed 26 Dec 2020] https://www.medicines.org.uk/emc/files/pil.4568.pdf
USEFUL DIAGNOSTIC TESTS
- Absolute Eosinophil Count
- Peripheral Smear Examination
- Total IgE
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