INTRODUCTION
TRISOLIV SYRUP is a combination of Tricholine citrate and Andrographis paniculata which belongs to the group of medicines called lipotropic and hepatoprotective respectively. It is used to treat liver dysfunctions, atonic constipation (decrease in bowel movements due to weakness of muscles of intestine), loss of appetite. It is also used in combination with Anti-Tuberculosis drug.
TRISOLIV SYRUP is not recommended for use if you have obstructive jaundice (yellowish discolouration of skin and eyes), multiple sclerosis (disease of the brain and spinal cord), systemic lupus erythematosus (the immune system attacks its own tissues) and rheumatoid arthritis (chronic inflammatory disease of hands and feet). Consult your doctor before taking it.
TRISOLIV SYRUP should be used with caution in patients with low blood pressure, bleeding problems. Consult your doctor before taking it.
TRISOLIV SYRUP is not recommended for use in pregnant and breastfeeding women. TRISOLIV SYRUP is safe to use in children and in infants. If you experience any side effects after taking TRISOLIV SYRUP, consult your doctor.
USES OF TRISOLIV SYRUP
Treats:
- liver dysfunctions
- atonic constipation
- loss of appetite
- co-treatment with Anti-Tuberculosis drugs
HOW TRISOLIV SYRUP WORKS
TRISOLIV SYRUP is a combination of Tricholine citrate and Andrographis paniculata. Tricholine citrate have lipotropic action and helps to remove excess fat from the liver and prevent excessive fat deposition in the liver and Andrographis paniculata provides liver protective action, choleretic action due to its ability to increase bile flow and helps in digestion by increasing in the flow of saliva, gastric juice and intestinal enzymes. Sorbitol is a laxative useful to prevent constipation and relieve the related symptoms. Thus, the combination is used to protect the liver and valuable in the management of liver dysfunction.
DIRECTIONS FOR USE
Take TRISOLIV SYRUP as advised by your physician. Shake well before use. Your physician will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedTRISOLIV SYRUP is not recommended for use in pregnant women. Consult your physician before taking it.
BREASTFEEDING
ContraindicatedTRISOLIV SYRUP is not recommended for use in breastfeeding women. Consult your physician before taking it.
LIVER
ContraindicatedTRISOLIV SYRUP is not recommended for use if you have obstructive jaundice (yellowish discolouration of skin and eyes). Consult your doctor before taking it.
ALLERGY
ContraindicatedDo not take TRISOLIV SYRUP if you are allergic to Tricholine citrate Andrographis paniculata or any of the other ingredients of this medicine.
HEART DISEASE
Use with CautionTRISOLIV SYRUP should be used with caution in patients with low blood pressure. Consult your doctor before taking it.
USE IN PEDIATRICS
SafeTRISOLIV SYRUP is safe to use in children and in infants. Consult your physician before taking it.
OTHERS
TRISOLIV SYRUP is not recommended for use if you:
- have multiple sclerosis (disease of the brain and spinal cord)
- have systemic lupus erythematosus (the immune system attacks its own tissues)
- have rheumatoid arthritis (chronic inflammatory disease of hands and feet)
Before taking TRISOLIV SYRUP, Inform your doctor if you:
- have bleeding problems
INTERACTIONS
A. Drug-Drug interactions:
Before taking TRISOLIV SYRUP, inform your doctor if you are taking any of the following medicine:
- medicines used to treat high blood pressure Ex. captopril, enalapril, valsartan, diltiazem
- medicines sued to decrease immune system Ex. azathioprine, cyclosporine
- medicines that slow down blood clotting Ex. aspirin, clopidogrel, heparin
Overdosage:
If you or anyone else accidentally took too much of this medicine, consult your physician immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Tricholine citrate and Andrographis paniculata |
| Pharmacological Category | : | Lipotropic and Hepatoprotective respectively |
| Therapeutic Indication | : | Liver dysfunctions, atonic constipation, loss of appetite and co-treatment in tuberculosis |
| Dosage Forms | : | Syrup |
MORE INFORMATION
- Keep TRISOLIV SYRUP out of reach of children
- Store at a room temperature
FAQs ABOUT TRISOLIV SYRUP
Q: What to do If I forget to take TRISOLIV SYRUP?
A: You should take TRISOLIV SYRUP immediately when you remember. If it is time for your next dose skip the dose and follow your regular dose schedule. Do not double the dose to match up your missed dose.
Q: How often can I take TRISOLIV SYRUP?
A: Take TRISOLIV SYRUP as advised by your physician. Shake well before use. Half teaspoonful (2.5ml) to be taken before food in infants, 1 teaspoonful (5ml) to be taken before meals in children and 2 teaspoonful (10ml) to be taken before meals in adults. Consult your doctor before taking it.
Q: How TRISOLIV SYRUP helps to treat liver disease?
A: TRISOLIV SYRUP is a combination of Tricholine citrate and Andrographis paniculata. Tricholine citrate have lipotropic action and helps to remove excess fat from the liver and prevent excessive fat deposition in the liver and Andrographis paniculata provides liver protective action, choleretic action due to its ability to increase bile flow and helps in digestion by increasing in the flow of saliva, gastric juice and intestinal enzymes. Sorbitol is a laxative useful to prevent constipation and relieve the related symptoms. Thus, the combination is used to protect the liver and valuable in the management of liver dysfunction.
Q: Is TRISOLIV SYRUP safe to take in pregnancy?
A: TRISOLIV SYRUP is not recommended for use in pregnant women. Inform your doctor if you are pregnant or planning to have a baby before taking this medicine.
Q: Who should not take TRISOLIV SYRUP?
A: TRISOLIV SYRUP is not recommended for use if you are allergic to Tricholine citrate Andrographis paniculata or any of the other ingredients of this medicine or if you have multiple sclerosis (disease of the brain and spinal cord), systemic lupus erythematosus (the immune system attacks its own tissues) and rheumatoid arthritis (chronic inflammatory disease of hands and feet). Consult your doctor before taking it.
REFERENCES
1. Ronald Ross Watson, Victor R. Preddy. Phytochemicals in the Prevention of Ethanol-Induced Hepatotoxicity: A Revisit. Dietary Interventions in Liver disease Foods, Nutrients and Dietary Supplements. 2019. Page – 85.
2. Bethesda (MD). Tricholine citrate. NIH. National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 22nd June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Tricholine-citrate
3. Md. Sanower Hossain, Zannat Urbi, Abubakar Sule and K. M. Hafizur Rahman. Andrographis paniculata (Burm. f.) Wall. ex Nees: A Review of Ethnobotany, Phytochemistry and Pharmacology. NIH National Library of Medicine, National Center for Biotechnology Information. December 2014. [Accessed on 22nd June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408759/
4. Arif A. Faruqui, Chandrakant Joshi, Wasim Siddique, Rahul Mahajan. Evaluation of Efficacy & Tolerability of Trisoliv® Syrup (Andrographolides + Tricholine Citrate + Sorbitol) in the Management of Various Liver Dysfunctions. International Journal of Pharmacy and Biological Sciences. March 2012. [Accessed on 22nd June 2022] https://www.ijpbs.com/ijpbsadmin/upload/ijpbs_50c867d570a9f.pdf
5. Trisoliv Syrup (Tricholine citrate and Andrographis paniculata). Medley Pharmaceuticals Pvt Ltd. [Accessed on 22nd June 2022] https://www.medleylab.com/product/Osteokare/hepatoprotective.html
6. Drugs.com. Andrographis. [Accessed on 22nd June 2022] https://www.drugs.com/npp/andrographis.html
7. RX list. Andrographis. [Accessed on 22nd June 2022] https://www.rxlist.com/andrographis/supplements.htm
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