TRIMEDOR 500MG contains Metformin hydrochloride which belongs to a group of medicines known as biguanides. Diabetes is a condition where the pancreas does not make enough insulin, a hormone which makes your body take in glucose (sugar) from the blood. This leads to a high level of glucose in your blood.
TRIMEDOR 500MG helps to lower your blood glucose to normal level. It is an antihyperglycemic agent used in patients with type 2 diabetes which improves glucose tolerance. In liver it suppresses hepatic gluconeogenesis (glycogen breaks down into glucose-1-phosphate and glycogen and glycogenolysis (breakdown of glycogen to glucose) which is responsible for lowering of blood glucose in diabetic patients.
Your doctor decides upon the dose depending on your age, other medications you take and based on your problems related to kidney or liver. This medicine is not recommended for breastfeeding mothers. The common side effects of TRIMEDOR 500MG are nausea, vomiting, headache, diarrhoea and abdominal pain. This medicine is suitable for children and adolescents over 10 years of age as recommended by your physician.
TRIMEDOR 500MG works by reducing the amount of sugar releases by liver into your blood. Metformin acts by decreasing glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin, thus helping in controlling the blood sugar level.
Always take TRIMEDOR 500MG exactly as instructed by your doctor. Take the medicine with or after a meal. It will avoid you from having side effects like affecting your digestion. Do not crush or chew the medicine. Swallow with a glass of water.
Stop taking TRIMEDOR 500MG and contact your doctor immediately if you experience symptoms of lactic acidosis because it can lead to coma
Feeling sick (nausea) or vomiting:
Try simple meals and do not eat oil rich or spicy foods.
Diarrhoea:
Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.
Abdominal pain:
Keep a hot water bottle or heated bag on your abdomen. Drink plenty of clear fluids and water.
TRIMEDOR 500MG should be used with caution in pregnant women. Consult your doctor before taking.
TRIMEDOR 500MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
TRIMEDOR 500MG should be used with caution while driving or operating machines since it can cause side effects related with low blood sugar such as increased sweating, fast heartbeat, vision changes, particularly when used with other diabetic drugs.
Avoid taking excessive alcohol during the treatment with TRIMEDOR 500MG since this may increase the risk of lactic acidosis.
TRIMEDOR 500MG is not recommended in patients with severe kidney disease. Consult your doctor for advice.
TRIMEDOR 500MG is not recommended in patients with severe liver disease. Consult your doctor for advice.
Do not take TRIMEDOR 500MG, if you are allergic (hypersensitive) to metformin hydrochloride or any of its other ingredients.
TRIMEDOR 500MG is not recommended in patients with severe heart disease. Consult your doctor for advice.
Inform your doctor if you have a condition such as uncontrolled diabetes (severe hyperglycaemia) and severe infection (lung or bronchial system)
Use in pediatrics:
TRIMEDOR 500MG can be used in children between 10 and 16 years of age. Consult your doctor for advice before initiating the treatment.
Use in geriatrics:
TRIMEDOR 500MG should be used with caution in elderly patients, especially, with kidney disease.
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:
Overdosage:
If you or anyone else accidentally took too much of TRIMEDOR 500MG, consult your doctor immediately. Overdose may cause symptoms such as very low blood sugar and increase the chance of developing lactic acidosis (buildup of lactic in blood).
Drug | : | Metformin |
Pharmacological Category | : | Biguanide |
Therapeutic Indication | : | Type II diabetes |
Dosage Forms | : | Tablet |
Store below 20-25°C and keep out of reach of children.
What does TRIMEDOR 500MG do exactly?
In type 2 diabetes, your body will not be able to make sufficient insulin or respond normally to the insulin made by your body. TRIMEDOR 500MG acts by decreasing glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin.
Can TRIMEDOR 500MG make you sleepy?
TRIMEDOR 500MG is usually well tolerated and does not cause sleepiness. But rarely, it causes sleep disorders and insomnia.
How to take TRIMEDOR 500MG?
Take TRIMEDOR 500MG with meal or after a meal. Do not crush or chew the medicine and swallow it with a glass of water. Always take as prescribed by your doctor.
Can TRIMEDOR 500MG cause low blood sugar levels? How to know its symptoms?
No, TRIMEDOR 500MG when used alone does not cause low blood sugar levels, when used in combination with other diabetic drugs or insulin may cause low blood sugar levels. Symptoms include increased sweating, visual disturbances, fast heartbeat, dizziness.
Can I take TRIMEDOR 500MG with alcohol?
No, taking TRIMEDOR 500MG with alcohol may alter your blood sugar levels and can cause serious side effects like lactic acidosis (excess build up of lactic acid in the blood). This medical condition should be treated only at the hospital. Usually, your doctor may warn about the symptoms of lactic acidosis.
1. KD Tripathi MD. Insulin, oral hypoglycaemic drugs and glucagon. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 275.
2. Powers AC, D Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. Page - 1258-1260.
3. Nolte MS. Pancreatic hormones and antidiabetic drugs. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page - 741-742.
4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 873-875.
5. Graham Rena, Grahame Hardie and Ewan R. The mechanisms of action of metformin: Diabetologia. Aug 3, 2017; [Accessed Oct 1, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552828/
6. Milpharm Limited, Electronic Medicines Compendium (EMC); [Revised July 2020] [Accessed Oct 1, 2020] https://www.medicines.org.uk/emc/files/pil.7347.pdf
7. Bristol-Myers Squibb Company. U.S. Food & Drug Administration; [Revised March 2014] [Accessed Oct 1, 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020357s037s039,021202s021s023lbl.pdf
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