Trehalube Eye Drops 10ml

INTRODUCTION

TREHALUBE contains Sodium hyaluronate which belongs to the group of medicines called ophthalmic lubricants. It is used to treat dry eyes caused by non-pathological conditions such as dust, smoke, dry heat, air conditioning, wind, cold, extended computer screen use or contact lens wear. It can also be used to treat eye dryness, burning, ocular fatigue and ocular damage caused by any underlying eye conditions such as superficial keratitis, Sjogren syndrome or primary dry eye syndrome.

Hyaluronic acid is a polysaccharide naturally present in the extracellular matrix of human connective tissue. It moistens, soothes and lubricates your eye, making it feel more comfortable and less irritated. This medicine is for ophthalmic use only. Avoid contact of this medicine with nose or mouth. Place 2-3 drops of this medicine into the affected eye. Do not touch the tip of the container with your eyes or fingers to avoid the spread of infection.

TREHALUBE is generally safe and does not cause any side effects. However, in some individuals it may cause mild eye irritation and blurred vision, which is usually temporary and disappears with the course of therapy. If you experience any other eye problems consult your doctor immediately. While using this medicine, do not wear soft contact lenses unless your doctor has advised you otherwise. It is considered safe for use in pregnant and lactating women. However, consult your doctor before taking.

USES OF TREHALUBE

• Treats dry eye

HOW TREHALUBE WORKS

Sodium hyaluronate is a salt form of hyaluronic acid. Hyaluronic acid is a polysaccharide naturally present in the extracellular matrix of human connective tissue. Ophthalmic application of hyaluronic acid binds to fibronectin and accelerates the adhesion and extension of ocular epithelial cells. It effectively moistens your eyes, accelerates wound healing of corneal epithelium and relieves your eyes from dryness, burning sensation and irritation.

DIRECTIONS FOR USE

Apply this medicine as directed by your physician. It is for ophthalmic use only. Wash your hands. Tilt your head slightly backwards and look upwards. Place the tip of the nozzle on the corner of the affected eye and place 2-3 drops of this medicine into the lower eyelid. Close your eyes for few seconds. Replace the cap tightly after use and wash your hands.

Do not touch the tip of the container with your eyes or fingers to avoid the spread of infection. Your doctor will decide the correct dose for you depending upon your condition. Continue to use this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF TREHALUBE

HOW TO MANAGE SIDE EFFECTS

Eye irritation or pain:

This is usually temporary and disappears after some time. Close your eyes and relax. Place an ice pack on top of the irritated eye which might relieve irritation. Avoid looking at systems, mobile phones, laptops and other light sources. If it does not get better, speak to your doctor.

Blurred vision:

This is usually temporary and disappears after some time. Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you experience visual disturbances. If the symptom still persists, contact your doctor for advice.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are using any other eye ointment or eye drops.

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT TREHALUBE

What are the uses of TREHALUBE?

It is used to treat dry eyes caused by non-pathological conditions such as dust, smoke, wind, extended computer screen use or contact lens wear. It moistens, soothes and lubricates your eye, making it feel more comfortable and less irritated.

Can TREHALUBE cause blurred vision?

Yes. It may cause blurred vision in some individuals. This is usually temporary and disappears after some time. Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you experience visual disturbances. If the symptom still persists, contact your doctor for advice.

How long should I use TREHALUBE to achieve better results?

Continue to use this medicine, as long as your doctor tells you to do so, to obtain better results. The treatment duration may vary from person to person depending upon the severity of the condition.

REFERENCES

1. HV Nema and Nitin Nema. Ocular Therapeutics. Textbook of Ophthalmology. 5th Edition. 2008. Page – 106.

2. HV Nema and Nitin Nema. Diseases of the Lacrimal Apparatus. Textbook of Ophthalmology. 5th Edition. 2008. Page – 409-412.

3. Alcon Research. Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on July 2013] [Accessed 17th December 2020] https://clinicaltrials.gov/ct2/show/NCT01382225

4. Bryan Chin Hou Ang, James Jie Sng, Priscilla Xin Hui Wang, Hla Myint Htoon and Louis Hak Tien Tong. Sodium Hyaluronate in the Treatment of Dry Eye Syndrome: A Systematic Review and Meta-Analysis. NCBI; PMC US National Library of Medicine, National Institute of Health. August 2017. [Accessed 17th December 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567178/

5. S Shimmura, M Ono, K Shinozaki, I Toda, E Takamura, Y Mashima, K Tsubota. Sodium hyaluronate eyedrops in the treatment of dry eyes. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. November 1995. [Accessed 17th December 2020] https://pubmed.ncbi.nlm.nih.gov/8534643/#:~:text=In%20the%20clinical%20study%20104,at%202%20and%204%20weeks.

6. Central Drugs Standard Control Organisation (CDSCO). Sodium hyaluronate eye drops (0.18%). [Revised on June 2005] [Accessed 17th December 2020] https://cdscoonline.gov.in/CDSCO/Drugs

7. TRB Chemedica (UK) Ltd. Vismed. [Accessed 17th December 2020] https://vismed.trbchemedica.co.uk/data/documents/Vismed%20Range%20SmPCs.pdf

8. Central Drugs Standard Control Organisation (CDSCO). Sodium hyaluronate eye drops (0.1%). [Revised on January 2009] [Accessed 17th December 2020] https://cdscoonline.gov.in/CDSCO/Drugs