INTRODUCTION

TRAPIC 650MG contains Tranexamic acid which belongs to a group of medicines called anti-fibrinolytic agents, which is used to stop or reduce unwanted bleeding. It is used to prevent or reduce bleeding for a short period of time in different conditions such as prostate surgery (post-prostatectomy), bladder surgery, heavy periods (menorrhagia), nose bleeds, cervical surgery, bleeding inside the eye, tooth removal haemophiliacs (people who bleed more easily than normal), angioneurotic oedema (hereditary disease).

Blood clots are formed by a protein called fibrin. There are enzymes in your body that break down fibrin which makes blood clots do not stay in place. This process is called "fibrinolysis". TRAPIC 650MG is an anti-fibrinolytic which helps prevent fibrinolysis by stopping the fibrin from being broken down. This prevents the breakdown of blood clots and helps them to stay in place where they are needed (excessive bleeding during periods, or after surgery).

Always take this TRAPIC 650MG exactly as prescribed by your doctor. Before taking this medicine, tell your doctor if you have liver, kidney or heart problems, pregnant women and breastfeeding mothers. Your doctor will prescribe the right dose depends on your child’s age and body weight. The common side effects are nausea, diarrhoea and stomach pain.

USES OF TRAPIC 650MG

• Prevent or reduce bleeding

HOW TRAPIC 650MG WORKS

Blood clots are formed by a protein called fibrin. There are enzymes in your body that break down fibrin which makes blood clots do not stay in place. This process is called "fibrinolysis". TRAPIC 650MG is an anti-fibrinolytic which helps prevent fibrinolysis by stopping the fibrin from being broken down. This prevents the breakdown of blood clots and helps them to stay in place where they are needed (excessive bleeding during periods, or after surgery).

DIRECTIONS FOR USE

Always take this TRAPIC 650MG exactly as your doctor has told you. Swallow as a whole, with a glass of water. Do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF TRAPIC 650MG

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to simple normal meals and do not eat rich or spicy foods.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Stomach pain:

Place a warm water bottle on your abdomen. Soak in a warm bath. Drink plenty of clear fluids and water.

WARNING & PRECAUTIONS

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

• streptokinase (used to dissolve blood clots)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT TRAPIC 650MG

How does TRAPIC 650MG stop bleeding?

It works by slowing the breakdown of blood clots, which helps to prevent prolonged bleeding.

Can TRAPIC 650MG cause infertility?

It is taken only during the menstrual cycle and does not interfere with ovulation. Thus, it can be used by women who desire fertility but are troubled by heavy bleeding.

Is TRAPIC 650MG effective?

Yes, it is effective if used in the correct dose and duration advised by your doctor.

REFERENCES

1. KD Tripathi MD. Drugs affecting blood and blood formation. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 628.

2. Zehnder JL. Drugs Used in Disorders of Coagulation. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. Page - 602.

3. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics.12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 867-868.

4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page - 1388-1389.

4. Ingrid Pabinger, Dietmar Fries, Herbert Schöchl, Werner Streif and Wolfgang Toller. Tranexamic acid for treatment and prophylaxis of bleeding and hyperfibrinolysis; [Accessed Dec 15, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429347/

5. Rivopharm UK Ltd. Laboratories BTT. Electronic Medicines Compendium (EMC); [Revised June 2018] [Accessed Dec 15, 2020] https://www.medicines.org.uk/emc/files/pil.2359.pdf