TRANEXAVAG Injection 5ml

Bleeding Disorders Rx required

Best Price* ₹ 62.58 MRP ₹ 78.22
(Inclusive of all taxes) * Mkt: PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

TRANEXAVAG contains Tranexamic Acid which belongs to the group of medicines called Antifibrinolytics. It is used in the prevention and treatment of bleeding in conditions such as heavy menstrual bleeding in women, gastrointestinal bleeding (bleeding in digestive tract, anywhere from the throat to rectum), bleeding due to thrombolytic therapy (medicine that is used to breakdown blood clots) and after having surgeries (such as ear, nose, throat, prostate gland, urinary tract, gynecological, abdominal or heart surgery) in adults and children above one year of age.   

TRANEXAVAG is not recommended for use in patients with severe kidney impairment, blood clotting disorder or consumption coagulopathy (condition affecting the blood’s ability to clot and stop the bleeding) or history of seizures (fits). Your doctor may recommend you to take relevant tests to understand your existing condition.

Before receiving TRANEXAVAG, inform your doctor if you had or have blood in the urine, are at risk of having a blood clot, excessive clotting or bleeding throughout the body (disseminated intravascular coagulation).

TRANEXAVAG is not recommended for use in the first trimester of pregnancy and in breast-feeding women. It should be used with caution in pregnant women only if clearly advised by the doctor. TRANEXAVAG should be used with caution in elderly patients, especially in patients with the evidence of renal failure. The most common side effects of receiving TRANEXAVAG are nausea or vomiting and diarrhea. Inform your doctor immediately if any of the side effect worsens.   

USES OF TRANEXAVAG

Prevent and treats bleeding in children (aged above one) and adults in conditions such as:

  • heavy menstrual bleeding in women
  • gastrointestinal bleeding
  • after having surgeries (such as ear, nose, throat, heart, abdominal, gynaecological and prostrate or urinary tract surgery)
  • bleeding due to medicine that is used to breakdown blood clots (thrombolytic therapy)

HOW TRANEXAVAG WORKS

TRANEXAVAG prevents bleeding by blocking the plasminogen from binding with fibrin which results in bleeding. As a result, it prevents and controls bleeding associated with various factors.

DIRECTIONS FOR USE

TRANEXAVAG will be given to you only by a doctor or a nurse into a vein as an intravenous injection. Your doctor will decide the correct dose, frequency and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF TRANEXAVAG

COMMON

  • diarrhoea
  • nausea, vomiting

UNCOMMON

  • skin rashes

RARE

Inform your doctor immediately if you experience any of the following side effects while receiving TRANEXAVAG:

  • severe allergic reaction (signs include redness of the skin and lumpy skin rashes, difficulty in breathing, swelling of face, mouth, lips or eyelids, unexplained high temperature (fever) and fainting)  
  • swelling of the throat that causes breathing and swallowing difficulty
  • symptoms of a blood clot (such as swelling or pain in the legs or chest, headache, weakness of the face and limbs on one side of the body)

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.

Diarrhoea:

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Inform your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY

TRANEXAVAG is not recommended for use in the first trimester of pregnancy. It should be used with caution in pregnant women only if considered clearly necessary. Women of childbearing potential should use effective contraception during treatment with this medicine. Consult your doctor before receiving TRANEXAVAG.

BREASTFEEDING

TRANEXAVAG is not recommended for use in breastfeeding women as it passes through breast milk. Consult your doctor for advice.

KIDNEY

TRANEXAVAG is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with mild to moderate kidney impairment. Your doctor may adjust the dose depending upon the kidney function. Consult your doctor before receiving TRANEXAVAG.    

LIVER

TRANEXAVAG can be used with caution in patients with liver impairment. Consult your doctor before receiving TRANEXAVAG.   

ALLERGY

Do not receive TRANEXAVAG if you are allergic to Tranexamic acid or any other ingredients of this medicine.

OTHERS

TRANEXAVAG is not recommended for use if you:

  • have blood clotting disorder or consumption coagulopathy (condition affecting the blood’s ability to clot and stop the bleeding)
  • have history of seizures (fits)

Before receiving TRANEXAVAG inform your physician if you:

  • have blood in the urine (which may lead to urinary tract obstruction)
  • are at risk of having a blood clot
  • have excessive clotting or bleeding throughout the body (disseminated intravascular coagulation)

Use in pediatrics:

TRANEXAVAG should be used with caution in children above 1 year of age. Your child’s doctor will adjust the dose based on the bodyweight of the child. Consult child’s doctor for advice before administration of TRANEXAVAG.

Use in geriatrics:

TRANEXAVAG should be used with caution in elderly patients, especially in patients with the evidence of renal failure. Consult your doctor before receiving TRANEXAVAG.

INTERACTIONS

A. Drug-Drug interactions:

Before receiving TRANEXAVAG inform your doctor if you have received or taking any of the following medicines:   

  • ethinyl estradiol, levonorgestrel (oral contraceptives used to prevent pregnancy)
  • thrombolytic agents such as streptokinase, reteplase, tenecteplase (medicines that prevent blood clot)
  • antifibrinolytics such as aminocaproic acid, aprotinin (medicines that help the blood to clot)

Overdosage:

TRANEXAVAG will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms contact your doctor immediately. Symptoms include dizziness, headache, low blood pressure and convulsions (fits).

SYNOPSIS

Drug :  

Tranexamic Acid

Pharmacological Category :  

Antifibrinolytics

Therapeutic Indication :  

Prevent and treats bleeding in certain conditions

Dosage Forms :  

Tablet, Gel, Injection

MORE INFORMATION

  • Store at room temperature

FAQs ABOUT TRANEXAVAG

Can TRANEXAVAG be used in elderly patients?

TRANEXAVAG should be used with caution in elderly patients, especially in patients with the evidence of renal failure. Consult your doctor for advice before receiving TRANEXAVAG.    

Is TRANEXAVAG safe to use during pregnancy?

TRANEXAVAG is not recommended for use in the first trimester of pregnancy. It should be used with caution in pregnant women only if clearly advised by the doctor. Women of childbearing potential should use effective contraception during treatment with this medicine. Consult your doctor before receiving TRANEXAVAG.

Can TRANEXAVAG be used in patients with impaired kidney function?

TRANEXAVAG is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients with mild to moderate kidney impairment. Your doctor may adjust the dose depending upon the kidney function. Consult your doctor before receiving TRANEXAVAG.    

Does TRANEXAVAG cause nausea?

Yes, TRANEXAVAG may cause nausea in some individuals. To manage this effect, stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.

How TRANEXAVAG is administered?

TRANEXAVAG will be given to you only by a doctor or a nurse into a vein as an intravenous injection. It should not be injected into a muscle (intramuscularly). Your doctor will decide the correct dose, frequency and duration for you depending upon your age, body weight and disease condition.

REFERENCES

1. KD. Tripathi. Drugs affecting blood and blood formation. Essentials of medical pharmacology. Eighth Edition. 2019. Page – 676.

2. John M. Chauncey, Jerald S. Wieters. Tranexamic Acid. NIH. National Library of Medicine, National center for biotechnology information. [Revised in January 2022] [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK532909/

3. Johnny Cai, Jessica Ribkoff, Sven Olson, Vikram Raghunathan, Hanny Al-Samkari, Thomas G. DeLoughery, and Joseph J. Shatzel. The many roles of tranexamic acid: An overview of the clinical indications for TXA in medical and surgical patients. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. December 2019 [Accessed on 14th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023891/

4. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in July 2022] [Accessed on 14th July 2022] https://www.medicines.org.uk/emc/files/pil.8953.pdf

5. Emcure Pharma UK Ltd. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 14th July 2022] https://www.medicines.org.uk/emc/product/11894/smpc

6. Medochemie Ltd. Electronic Medicines Compendium (EMC). [Revised in May 2018] [Accessed on 14th July 2022] https://www.medicines.org.uk/emc/files/pil.3374.pdf

USEFUL DIAGNOSTIC TESTS

  • Complete blood count
  • Liver function test
  • Kidney function test
  • Bleeding Time/clotting time
  • Eye test

PRODUCT DETAILS

    Country Of Origin
    India
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

TRANEXAVAG Injection 5ml

TRANEXAVAG Injection 5ml Mkt: PREVEGO HEALTHCARE & RESEARCH PRIVATE LIMITED

M.R.P.: Rs.78.22
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