INTRODUCTION

TOPCID 20MG TABLET contains Famotidine which belongs to the group of medicines called H2 receptor antagonists. It is used in treatment of stomach ulcers (gastric/duodenal ulcers), reflux esophagitis (irritation and inflammation caused by stomach acid leaking up into the oesophagus) and Zollinger-Ellison syndrome (recurrent tumours and ulcers in stomach and intestines).

Along with TOPCID 20MG TABLET, your doctor might ask you to take enough rest and drink plenty of fluids. Consuming simple foods and avoiding oily and spicy foods might be beneficial as well. Before starting the treatment with TOPCID 20MG TABLET, inform your doctor if you have a kidney disease, tumour in your stomach or are intolerant to certain sugars.

TOPCID 20MG TABLET should not be used in pregnant and breast-feeding women unless considered necessary by your doctor, therefore contact your doctor. TOPCID 20MG TABLET is not recommended for use in children. The most common side effects of using TOPCID 20MG TABLET are headache, dizziness, constipation and diarrhoea. Inform your doctor if any of the above side effects worsen.

USES OF TOPCID 20MG TABLET

Used to treat:

• stomach ulcers (gastric or duodenal ulcers)
• reflux oesophagitis
• zollinger−ellison syndrome (recurrent ulcers and tumours in the stomach and intestines)

HOW TOPCID 20MG TABLET WORKS

TOPCID 20MG TABLET effectively heals stomach ulcers by blocking certain receptors called Histamine (H2) receptors which are present in the stomach walls which in turn reduces the production of gastric acid and decreases the volume of gastric secretion in the stomach.

DIRECTIONS FOR USE

Take TOPCID 20MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF TOPCID 20MG TABLET

HOW TO MANAGE SIDE EFFECTS

Dizziness:

When you start taking TOPCID 20MG TABLET, you may feel faint or dizzy. This is caused by your blood pressure dropping. If this happens, resting or lying down for some time can help. Consult your doctor if symptoms don't improve. 

Headache:

Avoid bright lights, drink enough water and take a rest. Consult your doctor if symptoms don't improve. 

Constipation:

Eat plenty of fiber-rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Exercise more regularly. Consult your doctor if symptoms don't improve. 

Diarrhea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Consult your doctor if symptoms don't improve.

WARNING & PRECAUTIONS

PREGNANCY

TOPCID 20MG TABLET is not recommended for use in pregnant women or women planning to have a baby unless your doctor thinks the benefits outweigh the risks. Consult your doctor before taking it.

BREASTFEEDING

TOPCID 20MG TABLET is generally not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy or have a headache after taking TOPCID 20MG TABLET.

KIDNEY

TOPCID 20MG TABLET should be taken with caution in patients with kidney disease. The dose will be adjusted by your doctor. Consult your doctor before taking it.

ALLERGY

Do not take TOPCID 20MG TABLET if you are allergic to Famotidine or any other ingredients of this medicine.

INTERACTIONS

A. Drug – Drug Interactions:

• medicines used to treat fungal infections (Ex. ketoconazole, itraconazole)
• medicines used to treat gout (Ex. probenecid)
• antacids like aluminium hydroxide, calcium carbonate (medicines used to treat indigestion)
• medicines used to treat and prevent the recurrence of ulcers (Ex. sucralfate)
• medicines used for high blood phosphate levels in patients on dialysis (Ex. calcium carbonate)
• medicines used for treatment of HIV infection (Ex. atazanavir)

Overdosage:

If you or anyone else accidentally takes too much of TOPCID 20MG TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep TOPCID 20MG TABLET out of reach of children
• Store at room temperature not above 25°C

FAQs ABOUT TOPCID 20MG TABLET

Can I take TOPCID 20MG TABLET along with antifungal medicines like ketoconazole?

No, since TOPCID 20MG TABLET reduces the amount of acid in your stomach, antifungal medicines will not work well as it is best absorbed in an acidic environment. Consult your doctor before taking it.

Can TOPCID 20MG TABLET be used in pregnancy?

TOPCID 20MG TABLET is not recommended for use in pregnant women or women planning to have a baby unless your doctor thinks the benefits outweigh the risks. Consult your doctor before taking it.

What precautions do I have to take while taking TOPCID 20MG TABLET?

Patients taking TOPCID 20MG TABLET should inform the doctor if they have any kidney disease or tumor in the stomach. TOPCID 20MG TABLETis not recommended for use in pregnant and breastfeeding women. Consult your doctor before taking it.

What does TOPCID 20MG TABLET do?

TOPCID 20MG TABLET effectively heals stomach ulcers by blocking certain receptors called Histamine (H2) receptors which are present in the stomach walls which in turn reduces the production of gastric acid and decreases the volume of gastric secretion in the stomach.

Will TOPCID 20MG TABLET treat stomach pain?

No, TOPCID 20MG TABLET do not treat normal stomach pain. It is intended to treat stomach ulcers, reflux esophagitis and Zollinger-Ellison syndrome. By treating all these they provide relief to the patients but do not directly deal with stomach pain.

REFERENCES

1. KD. Tripathi. Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 650.

2. P A Abraham, J A Opsahl, C E Halstenson, A N Chremos, G R Matzke, W F Keane. The effect of famotidine on renal function in patients with renal insufficiency. NIH. National Library of Medicine, National centre for biotechnology information. Pubmed.gov. Sept 1987. [Accessed on 30th April 2022] https://pubmed.ncbi.nlm.nih.gov/2889461/#:~:text=These%20data%20suggest%20that%20famotidine,renal%20elimination%20of%20basic%20drugs.

3. Kim Nguyen, Graham D. Dersnah , Rajni Ahlawat. Famotidine. NIH. National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2022. [Accessed on 30th April 2022] https://pubmed.ncbi.nlm.nih.gov/30521199/

4. Kleva Pharmaceuticals S.A. Electronic Medicines Compendium (EMC). [Revised in Jan 2022] [Accessed on 30th April 2022] https://www.medicines.org.uk/emc/files/pil.11524.pdf

USEFUL DIAGNOSTIC TESTS

• Ultrasound
• Complete Blood Count (CBC)
• Gastrointestinal Endoscopy

AUTHOR DETAILS

Written By Dr. Shruthi M R, BDS
Last updated on 12 Jan 2023 | 10:13 AM(IST)