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Toflox 200mg Tablet 10'S
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INTRODUCTION
TOFLOX 200MG TABLET contains Ofloxacin, which belongs to the group of medicines called Antibiotics. It is used to treat and prevent various bacterial infections involving the respiratory system, urinary system (kidneys and bladder), both male and female genital organs (such as gonorrhoea), ears, nose, skin and soft tissues. Bacterial infections are generally characterized by fever, extreme tiredness, swollen lymph nodes in the neck, armpits, groin or elsewhere, headache, nausea or vomiting.
Avoid consumption of alcohol while taking TOFLOX 200MG TABLET, as it can make you feel dizzy or sleepy. Before recommending TOFLOX 200MG TABLET your doctor may advise you to take relevant tests to understand your condition.
TOFLOX 200MG TABLET is not recommended for use if you have fits or ever had swollen tendons. Before taking TOFLOX 200MG TABLET, inform your doctor if you have liver, kidney, heart, mental health problems, myasthenia gravis or diabetes. TOFLOX 200MG TABLET is not recommended for use by pregnant and breastfeeding women, children or adolescents (less than 18 years old). Consult your doctor before taking TOFLOX 200MG TABLET.
The most common side effects of taking TOFLOX 200MG TABLET are sleep problems, headache, dizziness, nausea, vomiting, diarrhoea, itching, external genital itching (women), vaginal inflammation and taste changes. Contact your doctor if any of your symptoms get worse or persist.
USES OF TOFLOX 200MG TABLET
- Treats and prevents bacterial infection in adults
HOW TOFLOX 200MG TABLET WORKS
TOFLOX 200MG TABLET works by binding to and inhibiting bacterial enzymes required in DNA synthesis, thus interrupting DNA replication and preventing bacterial cell multiplication.
DIRECTIONS FOR USE
Take TOFLOX 200MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition. Do not stop taking TOFLOX 200MG TABLET unless your doctor advises you to stop.
SIDE EFFECTS OF TOFLOX 200MG TABLET
COMMON
- sleep problems
- headache, dizziness
- nausea, vomiting, diarrhoea
- itching
- external genital itching (women)
- vaginal inflammation
- taste changes
UNCOMMON
- stomach pains
- irritated or burning eyes
- spinning sensations
- agitation, restlessness
- cough, sore nose or throat
- fungal infection
- skin rash or itching
RARE
- loss of appetite
- fast heartbeat
- drowsiness
- confusion, anxiety, nightmares, seeing, feeling or hearing things that are not there, mental illness
- changed or loss of smell
- altered liver enzymes or bilirubin levels
- too much sweating, hot flushes
- changes in kidney function tests
- low blood pressure (light-headedness, dizziness)
- hives, rash with pimples
Stop taking TOFLOX 200MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- treatment resistance (no response to treatment)
- allergic reaction (severe rash, sudden wheezing, trouble swallowing or breathing, swelling of your lips, face, throat or tongue)
- watery diarrhoea, probably with blood in it, with stomach cramps and fever
- swollen tendons with pain, tenderness and sometimes restricted movement like in the Achilles tendon
- nerve damage (pain, burning, numbness, tingling or weakness in the hands and feet, touch sensitivity)
- blurred, double or changed colour vision
- anaemia (tiredness, dizziness, breathless when exercising, pale skin)
- drop in numbers of different types of blood cells (fever, chills, sore throat, ulcers in the mouth and throat)
- erythema multiforme (skin rash, which may blister, looks like dark spots surrounded by a lighter area or surrounded with a dark ring)
- toxic epidermal necrolysis (a widespread rash with blisters and skin peeling on most of the body surface)
- narrowing, blockage or leakage of blood vessels, sometimes leading to severe skin reactions and death of skin areas
- severe kidney problems (rash, fever, general aches and pains, bloody urine)
- hearing problems or loss
- liver problems like hepatitis or blockage in the bile duct (yellow eyes or skin, nausea, vomiting, loss of appetite, feeling generally unwell, fever, itching, pale faeces, dark urine, tender stomach)
- prolongation of QT interval (abnormal, fast, irregular or abnormal heart rhythm)
- depression with thoughts of harming or killing self
- Stevens-Johnson syndrome (a widespread rash with blisters and peeling skin, specifically around the mouth, nose, eyes and genitals)
- swelling of the lungs (coughing, trouble breathing, wheezing)
- rhabdomyolysis (temporary paralysis or weakness of the muscles, with pain and tenderness
- porphyria attack in patients with porphyria (a rare blood pigment disorder)
- muscle or ligament breakdown
- inflamed pancreas (severe pain in the stomach and back)
- loss of consciousness due to a severe drop in blood sugar levels
- uveitis (inflammation of the eye)
- exfoliative dermatitis (skin redness with too much scaling)
- aortic aneurysm and dissection (sudden, severe pain in your stomach, chest or back)
- fits
HOW TO MANAGE SIDE EFFECTS
Nausea:
Take TOFLOX 200MG TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If your symptom gets worse or persist, consult your doctor immediately.
Vomiting:
Get adequate rest. Drink lots of fluids, especially water. Have small sips if you feel sick. Eat when you feel like it – you do not need to eat or avoid any specific foods. Do not take medicines on your own to treat vomiting without consulting your doctor. If your symptom gets worse or persist, consult your doctor immediately.
Headache:
Drink an ample amount of water. Get adequate rest. Try to be relaxed and stress-free. Do not take medicines on your own to treat a headache without consulting your doctor. If your symptom gets worse or persist, consult your doctor immediately.
Dizziness:
Lie down until the dizziness subsides, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol and drugs. If your symptom gets worse or persist, consult your doctor immediately.
Diarrhoea:
Drink lots of fluids, like water or fruit juice to keep yourself hydrated. Do not take medicines on your own to treat diarrhoea without consulting your doctor. If your symptom gets worse or persist, consult your doctor immediately.
Skin itching:
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. If your symptom gets worse or persist, consult your doctor immediately.
WARNING & PRECAUTIONS
PREGNANCY
TOFLOX 200MG TABLET is not recommended for use by pregnant women. Consult your doctor before taking it.
BREASTFEEDING
TOFLOX 200MG TABLET is not recommended for use by breastfeeding women. Consult your doctor before taking it.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you experience sleepiness, dizziness or problems with your eyesight after taking TOFLOX 200MG TABLET.
ALCOHOL
Avoid consumption of alcohol while taking TOFLOX 200MG TABLET as it might make you feel dizzy or sleepy.
KIDNEY
TOFLOX 200MG TABLET should be taken with caution in patients with kidney disease. Consult your doctor before taking it.
LIVER
TOFLOX 200MG TABLET should be taken with caution in patients with liver disease. Consult your doctor before taking it.
ALLERGY
Do not take TOFLOX 200MG TABLET if you are allergic to Ofloxacin or any of the other ingredients in this medicine or previously had an allergic reaction to any quinolone antibiotic.
HEART DISEASE
TOFLOX 200MG TABLET should be used with caution in patients with heart disease or problems with a heartbeat, aortic aneurism (an enlarged or bulged large blood vessel), aortic dissection (tear in the aortic wall) or family history of it, vascular Ehlers-Danlos syndrome, vascular disorders like Takayasu arteritis, giant cell arteritis, Behcet’s disease, high blood pressure, atherosclerosis, endocarditis, prolonged QT interval, very slow heart rhythm, a weak heart or a history of a heart attack. Consult your doctor before taking TOFLOX 200MG TABLET.
OTHERS
TOFLOX 200MG TABLET is not recommended for use if you:
- have or are at risk of fits
- ever had swelling of the tendons which can affect the wrist or the Achilles tendon
- have glucose-6-dehydrogenase deficiency (a problem with your red blood cells) or with a family history of glucose-6-dehydrogenase deficiency
Before taking TOFLOX 200MG TABLET, inform your doctor if you:
- have connective tissue problems like Marfan syndrome
- have Turner syndrome (a genetic disorder)
- have Sjogren’s syndrome (an autoimmune disease)
- have myasthenia gravis (muscle weakness and excessive muscle fatigue)
- have diabetes (high blood sugar)
- have a salt imbalance (low blood potassium or magnesium levels)
- have or ever had any mental health problems
Use in pediatrics:
TOFLOX 200MG TABLET is not recommended for use by children and adolescents (under 18 years of age). Consult your doctor before taking it.
Use in geriatrics:
TOFLOX 200MG TABLET should be used with caution by elderly patients. Consult your doctor before taking it.
INTERACTIONS
A. Drug-Drug interactions:
Before taking TOFLOX 200MG TABLET, inform your doctor if you are taking any of the following medicines:
- medicines used to treat irregular heartbeat (Ex. disopyramide, amiodarone, sotalol quinidine, hydroquinidine, dofetilide, ibutilide, procainamide)
- other medicines used to treat bacterial infections (Ex. erythromycin, clarithromycin, azithromycin)
- medicines used to treat depression (Ex. amitriptyline, clomipramine, imipramine)
- medicines used to treat psychiatric disorders (Ex. risperidone, quetiapine)
- medicines containing iron or zinc
- sucralfate (used to treat stomach ulcers)
- medicines used to treat indigestion (Ex. magnesium carbonate, aluminium hydroxide)
- medicines used to treat inflammation (Ex. hydrocortisone, prednisolone)
- medicines used to relieve pain and inflammation (Ex. ibuprofen, diclofenac)
- theophylline (used to treat breathing problems)
- methotrexate (used to treat rheumatism)
- glibenclamide (used to treat diabetes)
- probenecid (used to treat gout)
- cimetidine (used to treat stomach ulcers or acidity)
- medicines used to prevent blood clotting (Ex. warfarin, heparin)
- didanosine (used to treat HIV)
- furosemide (used to treat water retention)
Overdosage:
If you or anyone else accidentally take too much of TOFLOX 200MG TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are confusion, dizziness, loss of consciousness, fit and nausea.
SYNOPSIS
| Drug | : | Ofloxacin |
| Pharmacological Category | : | Quinolone antibiotics |
| Therapeutic Indication | : | Treats and prevents bacterial infection |
| Dosage Forms | : | Tablet, Solution, Eye ointment, Eye/Ear drops, Injection, Infusion, Syrup, Suspension, Cream |
MORE INFORMATION
- Keep TOFLOX 200MG TABLET out of reach from children
- Store below 30°C
FAQs ABOUT TOFLOX 200MG TABLET
Does TOFLOX 200MG TABLET treat urinary tract infections?
Yes. TOFLOX 200MG TABLET is used to treat urinary tract infections. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Does TOFLOX 200MG TABLET make you feel sleepy?
Yes. Avoid consumption of alcohol and do not drive or use any machines during treatment with TOFLOX 200MG TABLET as it can make you feel dizzy or sleepy.
Can TOFLOX 200MG TABLET treat typhoid?
According to some studies, TOFLOX 200MG TABLET can be used to treat typhoid in adults who are infected with S. typhi resistant to other medicines like chloramphenicol, ampicillin and cotrimoxazole. However, consult your doctor before taking TOFLOX 200MG TABLET.
Can TOFLOX 200MG TABLET make me feel suicidal?
TOFLOX 200MG TABLET might come with a risk of suicidal thoughts or actions. If at any time you have this kind of thought, immediately contact your doctor or go to the nearby hospital.
Can TOFLOX 200MG TABLET cause itching?
Yes. TOFLOX 200MG TABLET may cause itching along with rashes. In such cases, avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your symptom does not improve.
Can TOFLOX 200MG TABLET be taken by children?
No. TOFLOX 200MG TABLET is used for adults and is not recommended for children and adolescents below 18 years of age. Your doctor will decide the correct dose or select a suitable alternative therapy for your child.
What if I forget to take a dose of TOFLOX 200MG TABLET?
If you forget to take a dose of TOFLOX 200MG TABLET, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take the medicine twice to make up for the missed dose.
Can TOFLOX 200MG TABLET be stopped?
Continue taking TOFLOX 200MG TABLET until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. In such a case, contact your doctor right away. Do not stop taking TOFLOX 200MG TABLET just because you feel better. If you do so, your infection may get worse again.
Can TOFLOX 200MG TABLET be taken in pregnancy?
TOFLOX 200MG TABLET is not recommended for use in pregnancy. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before taking this medicine. Inform your doctor immediately if you become pregnant during treatment with TOFLOX 200MG TABLET.
Can TOFLOX 200MG TABLET be crushed?
No. TOFLOX 200MG TABLET should not be broken, crushed or chewed. Simply swallow it as a whole with a glass of water.
Can I take other medicines with TOFLOX 200MG TABLET?
Before taking TOFLOX 200MG TABLET, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicine, as these might interact with each other and cause serious side effects.
Can TOFLOX 200MG TABLET cause nausea?
Yes. If you feel nauseous, take TOFLOX 200MG TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. If your symptom gets worse or persist, contact your doctor immediately.
Can I drive a car after taking TOFLOX 200MG TABLET?
Do not drive if you experience sleepiness, dizziness or problems with your eyesight after taking TOFLOX 200MG TABLET. Consult your doctor if you feel any side effects during treatment with TOFLOX 200MG TABLET that may stop you from driving or using machines.
REFERENCES
1. K D Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of Medical Pharmacology. 7th edition. 2013. Page – 713.
2. Derrick B. Graham; Jayson Tripp. Ofloxacin. StatPearls [Internet]. StatPearls Publishing. March 2022. [Accessed on 9th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK549837/
3. Grassi GG. A multicenter study on clinical efficacy of ofloxacin in respiratory and urinary tract infections. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 1986. [Accessed on 9th July 2022] https://pubmed.ncbi.nlm.nih.gov/3546149/
4. Ishaq M, Farooqui BJ, Ashfaq MK, Khan MA. Therapeutic implications of ofloxacin in the treatment of typhoid fever caused by multiply resistant Salmonella typhi. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. August 1990. [Accessed on 9th July 2022] https://pubmed.ncbi.nlm.nih.gov/2126297/#:~:text=We%20concluded%20that%20ofloxacin%20can,to%20chloramphenicol%2C%20ampicillin%20and%20cotrimoxazole.
5. Gerard Laboratories. Electronic Medicines Compendium (EMC). [Revised in November 2021] [Accessed on 9th July 2022] https://www.medicines.org.uk/emc/files/pil.8481.pdf
6. Ortho-McNeil Pharmaceutical, Inc. U.S. Food & Drug Administration. [Revised in September 2008] [Accessed on 9th July 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019735s059lbl.pdf
7. Central Drugs Standard Control Organization (CDSCO). [Accessed on 9th July 2022] https://cdscoonline.gov.in/CDSCO/Drugs
USEFUL DIAGNOSTIC TESTS
- Bacterial culture
- Microscopic examination
- Completed Blood Count (CBC)
AUTHOR DETAILS
Written By Dr. Dhivakaran R, BDS
Last updated on 05 Oct 2022 | 04:07 PM(IST)
PRODUCT DETAILS
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