THALIDON 12.5 Tablet 10's

Hypertension Rx required
OUT OF STOCK

Best Price* ₹ 40.00 MRP ₹ 50.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mkt: Johnlee Pharmaceuticals Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

THALIDON 12.5 contains Chlorthalidone which belongs to the group of medicines called Diuretics. It is used to treat hypertension (high blood pressure) and heart failure. It also reduces fluid accumulation (edema) from the body that is caused due to certain liver or kidney diseases.

It also helps in the treatment of diabetes insipidus. Diabetes insipidus is a very rare condition in which the patient experiences excessive loss of fluids from the body in the form of urine. It happens due to problems in the pituitary hormones (such as vasopressin).

Chlorthalidone is a thiazide diuretic. It removes the extra water and certain electrolytes from the body. This reduces edema and other heart problems such as high blood pressure or heart failure. It can also control fluid loss in patients who are already experiencing loss of water from the body (such as in diabetes insipidus) by making the kidneys produce less urine.

Before taking THALIDON 12.5, inform your doctor if you have any kidney or liver problems, problems in urination, having gout, diabetes mellitus or if you are on a low-salt diet. THALIDON 12.5 is not recommended for use in women who are pregnant, planning to become pregnant or on breastfeeding.

THALIDON 12.5 may make you feel dizzy while standing up or moving suddenly. Therefore, be cautions while you drive or operate any heavy tools.

It may also alter the levels of certain electrolytes (such as magnesium, potassium, sodium, and chloride) in the body which may cause such as muscle weakness, muscle twitching, abnormal heartbeat, tiredness, confusion, or headache. To avoid this, your doctor will closely monitor your serum electrolyte levels periodically during treatment with THALIDON 12.5.

USES OF THALIDON 12.5

Used to treat:

  • hypertension
  • fluid retention (edema)
  • heart failure
  • diabetes insipidus

HOW THALIDON 12.5 WORKS

THALIDON 12.5 removes extra excess fluids from the body. It acts by preventing the reabsorption of sodium and chloride in the kidneys. This relaxes blood vessels and reduces elevated blood pressure. It also improves blood flow through the blood vessels and protect the functions of heart.

On a contrary, THALIDON 12.5 can also control fluid loss in patients who are already experiencing loss of water and electrolytes from the body (such as in diabetes insipidus). During conditions with excessive fluid loss, preventing of sodium and chloride reabsorption in the kidneys by chlorthalidone would make the kidneys produce less urine and therefore controls fluid loss in patients with diabetes insipidus.

DIRECTIONS FOR USE

Take THALIDON 12.5 as advised by your physician. Swallow THALIDON 12.5 with a glass of water. Do not crush or chew THALIDON 12.5. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking THALIDON 12.5 unless your doctor advises you to stop.

SIDE EFFECTS OF THALIDON 12.5

COMMON

  • signs of low blood potassium levels (such as muscle weakness, muscle twitching or abnormal heartbeat)
  • signs of low blood sodium levels (such as tiredness, confusion, muscle twitching, fits)
  • signs of high blood sugar levels (such as tiredness, weakness or feeling thirsty)
  • nettle rash, skin rash
  • low blood pressure (feeling dizzy while standing up)
  • loss of appetite
  • upset stomach
  • impotence in men

UNCOMMON

  • gout (painful and swollen joints)

RARE

  • increased blood calcium levels (causing anxiety, eye pain, stomach pain)
  • jaundice (yellowing of the skin or eyes caused by liver or blood problems)
  • abnormal heartbeat (fast, irregular heartbeats and fainting)
  • tingling sensation
  • headache
  • nausea, vomiting, stomach pain
  • constipation, diarrhoea
  • low CBC levels making you bleed or bruise easily or to get infected more often
  • breathing difficulties

HOW TO MANAGE SIDE EFFECTS

Headache:  

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Constipation:

Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

WARNING & PRECAUTIONS

PREGNANCY

THALIDON 12.5 is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.

BREASTFEEDING

THALIDON 12.5 is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel dizzy after taking THALIDON 12.5.

KIDNEY

THALIDON 12.5 is not recommended for use in patients with severe kidney problems like kidney stones, or if you are not passing any urine at all. Therefore, consult your doctor before taking it.

LIVER

THALIDON 12.5 is not recommended for use in patients with severe liver problems. It should be used with caution in any other liver problems. Therefore, consult your doctor before taking it.

ALLERGY

Do not take THALIDON 12.5 if you are allergic to Chlorthalidone.

HEART DISEASE

THALIDON 12.5 should be used with caution in patients with heart problems other than high blood pressure or heart failure. Therefore, consult your doctor before taking it.

OTHERS

THALIDON 12.5 is not recommended for use if you:

  • have low levels of sodium, potassium, or calcium in the blood
  • ever had gout
  • have Addison’s disease (a condition where your adrenal gland does not work properly)

Before taking THALIDON 12.5, inform your doctor if you:

  • are on a low-salt diet
  • have diabetes mellitus (increased blood sugar levels caused due to insulin deficiency)
  • have high cholesterol levels
  • experience trouble in vision or eye pain

Use in pediatrics:

THALIDON 12.5 should be used with caution in children and adolescents (below 18 years). Therefore, consult your doctor before taking it. Proper dose adjustments and careful monitoring are required in such patients.

Use in geriatrics:

THALIDON 12.5 should be used with caution in elderly patients. Therefore, consult your doctor before taking it. Proper dose adjustments and careful monitoring are required in such patients.

INTERACTIONS

A. Drug-Drug Interaction:

Before taking THALIDON 12.5, inform your doctor if you are taking any of the following:

  • medicines used to treat heart problems such as high blood pressure (Ex. lisinopril, propranolol, methyldopa, bosentan, amlodipine, guanethidine)
  • medicines used to treat allergic and inflammatory conditions and immune reactions (Ex. prednisolone, betamethasone)
  • adrenocorticotropic hormone (used to treat deficiency of cortisol in the body)
  • medicines used to treat cancer (Ex. cyclophosphamide, methotrexate)
  • medicines used to treat asthma (Ex. salbutamol, formoterol)
  • amphotericin B (a medicine used to treat fungal infections)
  • carbenoxolone (a medicine used to treat ulcers)
  • medicines used to treat high blood sugar levels (Ex. insulin, chlorpropamide, glibenclamide)
  • digoxin (a medicine used to treat irregular heartbeat)
  • lithium (a medicine used to treat mental illness)
  • medicines used to treat stomach spasms or cramps (Ex. atropine, hyoscine)
  • colestyramine (a medicine used to lower cholesterol levels and prevent heart disease)
  • amantadine (a medicine used to treat Parkinson’s disease, viral infections)
  • allopurinol (a medicine used to treat gout)
  • medicines used to relieve pain or treat rheumatism (Ex. aspirin, indomethacin)
  • ciclosporin (a medicine used to prevent graft rejection or auto-immune diseases)
  • medicines used for replacement therapy (Ex. calcium salts or vitamin D)

B. Drug-Food Interaction:

Avoid low-salt diet while taking THALIDON 12.5 as it may reduce the amount of salt in your body.

Overdosage:

If you or anyone else accidentally took more THALIDON 12.5, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug :   Chlorthalidone
Pharmacological Category :   Thiazide diuretic
Therapeutic Indication :   Hypertension, Fluid retention, Heart Failure, Diabetes insipidus
Dosage Forms :   Tablet

MORE INFORMATION

  • Keep THALIDON 12.5 out of reach of children
  • Store THALIDON 12.5 at room temperature

FAQs ABOUT THALIDON 12.5

How THALIDON 12.5 should be taken? Can it be crushed?

No. Take THALIDON 12.5 as advised by your physician. Swallow THALIDON 12.5 with a glass of water. Do not crush or chew the medicine.

Can THALIDON 12.5 cause hypokalaemia?

Yes. THALIDON 12.5 may cause hypokalaemia (low blood potassium levels) in some individuals. It can be identified by symptoms such as muscle weakness, muscle twitching or abnormal heartbeat. Consult your doctor immediately if you experience any such symptoms after taking THALIDON 12.5.

Can THALIDON 12.5 cause hyponatremia?

Yes. THALIDON 12.5 may cause hyponatremia (low blood sodium levels) in some individuals. It can be identified by symptoms such as tiredness, confusion, muscle twitching, or fits. Consult your doctor immediately if you experience any such symptoms after taking THALIDON 12.5.

What if I forget to take a dose of THALIDON 12.5?

If you forget to take a dose of THALIDON 12.5, take it as soon as you remember. However, if it is time to take the next dose, skip the missed one and take the next dose at regular time. Do not take a double dose of THALIDON 12.5 to make up the forgotten dose.

What precautions do I need to follow while taking THALIDON 12.5?

Before taking THALIDON 12.5 inform your doctor if you have liver, kidney, or heart problems. You should also inform your doctor if you have gout, diabetes mellitus or if you are on a low-salt diet. Consult your doctor before taking THALIDON 12.5 if you are pregnant, planning to become pregnant or breastfeeding. THALIDON 12.5 may make you feel dizzy while standing up or moving suddenly. Therefore, be cautions while you drive or operate any heavy tools. Inform your doctor if you experience any unusual tiredness, muscle problems, abnormal heartbeat, or extreme thirst.

Can the use of THALIDON 12.5 cause sexual problems?

Yes. THALIDON 12.5 may cause problems in sexual life. It may cause difficulty in getting an erection or achieving orgasm in men. Consult your doctor if this side effect troubles you.

Is it safe to take THALIDON 12.5 in pregnancy?

THALIDON 12.5 is not recommended for use in pregnancy. Inform your doctor before taking THALIDON 12.5 if you are pregnant or trying to become pregnant.

What are the side effects of THALIDON 12.5?

The most common side effects of taking THALIDON 12.5 are muscle weakness and twitching, abnormal heartbeat, tiredness, confusion, loss of appetite, upset stomach, dizziness, thirst, skin rash, and impotence in men. Contact your doctor if any of the side effect troubles you.

What is the effect of THALIDON 12.5 on kidneys?

THALIDON 12.5 belongs to the group of medicines called diuretics. It acts excreting excess fluids from the body. This relaxes blood vessels and reduces elevated blood pressure. It also improves blood flow through the blood vessels and protect the functions of heart. At times, it can also control fluid loss from the body in patients suffering from excess fluid loss such as diabetes insipidus. Since THALIDON 12.5 acts on your kidneys, consult your doctor before taking them if you have any kidney problems.

What type of diuretic is THALIDON 12.5?

THALIDON 12.5 belongs to thiazide-like diuretics which is indicated to treat high blood pressure, heart failure, diabetes insipidus. It can also reduce fluid retention that is caused due to kidney or liver disease.

Can potassium be taken with THALIDON 12.5?

Before taking potassium supplements or medicines containing potassium along with THALIDON 12.5, inform your doctor as a precaution. Your doctor would closely monitor your health condition to avoid unwanted side effects.

REFERENCES

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Heart Failure. Hypertension. Pharmacotherapy Handbook. Ninth edition. Page-75, 87.

2. Connor C. Kerndt; Jayesh B. Patel. Chlorthalidone. NIH. National Library of Medicine. National Center of Biotechnology Information. PMC PubMed Central. [Revised in May 2022]. [Accessed on 16th June 2022] https://www.ncbi.nlm.nih.gov/books/NBK553174/

3. Stela Dineva, Katya Uzunova, Velichka Pavlova, Elena Filipova, Krassimir Kalinov, and Toni Vekov. Comparative efficacy and safety of chlorthalidone and hydrochlorothiazide—meta-analysis. NIH. National Library of Medicine. National Center of Biotechnology Information. PMC PubMed Central. October 2018. [Accessed on 16th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892412/

4. Atlantic Pharma, S.A. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed 6th May 2022] https://www.medicines.org.uk/emc/files/pil.11981.pdf

5. Johnlee Pharmaceutical Pvt Ltd. Thalidon 6.25 mg. [Accessed on 16th June 2022] https://johnleeindia.com/product/thalidon-6-25/

6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 9th May 2022] https://cdscoonline.gov.in/CDSCO/Drugs

USEFUL DIAGNOSTIC TESTS

  • Complete Blood Count (CBC)
  • ECG

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    17.5 g
    Ingredient
    CHLORTHALIDONE 12.5 mg
    Hsn Code
    30049079
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