Tetglob 250IU Injection 1's

Tetanus Rx required
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Best Price* ₹ 930.76 MRP ₹ 1,163.45
(Inclusive of all taxes) * Mkt: Bharat Serums & Vaccines Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

TETGLOB 250IU contains Tetanus Immunoglobulin which belongs to the group of medicines called Immunoglobulins. It is used to prevent tetanus infection following injuries in patients who are at risk of getting infected with tetanus causing germs. It can also be used in patients who did not receive tetanus vaccine over the last 10 years or in patients who don’t remember about their vaccination status. TETGLOB 250IU is also used in the treatment of active tetanus infection. It is always administered along with tetanus vaccine for improved effects.

Tetanus (also known as lock jaw) is a serious bacterial infection caused by the bacterium called Clostridium tetani. It locks the muscles of the jaw and neck of the infected patients and makes it hard for them to open their mouth or swallow.

Tetanus immunoglobulin contains antibodies that are prepared from the blood samples of the screened donors. These antibodies bind to the tetanus causing germs and prevents them from attacking the nervous system. As a result, it prevents painful muscle spasms and other conditions associated with tetanus.

Do not receive TETGLOB 250IU if you are allergic to tetanus immunoglobulin or other immunoglobulins. Before receiving TETGLOB 250IU inform your doctor if you are severely dehydrated or have diabetes, high blood pressure or blood clots in the body. You must also inform your doctor if you got vaccinated recently or scheduled for any upcoming vaccination.

Consult your doctor before receiving TETGLOB 250IU if you are pregnant and breastfeeding. TETGLOB 250IU can be used in children if prescribed by the physician. The most common side effects of TETGLOB 250IU are pain, redness or swelling at the injection site, fever, joint pain, or mouth ulcers. Consult your doctor if any of the side effect worsens.

USES OF TETGLOB 250IU

  • Treats and prevents tetanus infection

HOW TETGLOB 250IU WORKS

TETGLOB 250IU offers protection against tetanus causing germs by supplementing our body with sufficient antibodies that is required to fight against the infection. The immunoglobulins (antibodies) present in the medicine binds to the tetanus causing germs and prevents them from attacking the nervous system. As a result, TETGLOB 250IU prevents painful muscle spasms and other conditions associated with tetanus.

DIRECTIONS FOR USE

TETGLOB 250IU will be given to you only by a doctor or nurse into the muscles (intramuscularly) of thighs or buttocks. Your doctor will decide the correct dose for you depending upon your age, body weight and severity of infection.

SIDE EFFECTS OF TETGLOB 250IU

COMMON

  • injection site reactions (pain, redness or swelling)
  • fever
  • dizziness
  • joint pains
  • mouth ulcers
  • feeling unwell or shaky

Contact your doctor immediately, if you experience any of the following side effects after receiving TETGLOB 250IU:

  • signs of allergic reactions (such as skin rash, itching, swelling of the face, or shortness of breath)

HOW TO MANAGE SIDE EFFECTS

Injection site reactions:

Place an ice pack on the injected site. Do not move the affected area frequently. If the symptom worsens, consult your doctor.

Fever:

Rest and relax. Drink plenty of fluids. Avoid taking cold bath or showers. If the fever prolongs for a longer time, consult your doctor immediately.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Mouth ulcers:

Avoid eating spicy foods. Drink plenty of fluids. Consult your doctor for a suitable oral pain-relieving gel containing lignocaine, triamcinolone, or choline salicylate.

WARNING & PRECAUTIONS

PREGNANCY

TETGLOB 250IU should be used with caution in pregnant women. Therefore, consult your doctor before receiving it.

BREASTFEEDING

TETGLOB 250IU should be used with caution in breastfeeding women. Therefore, consult your doctor before receiving it.

DRIVING AND USING MACHINES

TETGLOB 250IU is unlikely to affect your ability to drive or operate heavy tools or machines.

ALCOHOL

Avoid consumption of alcohol while receiving TETGLOB 250IU.

ALLERGY

Do not receive TETGLOB 250IU if you are allergic to Tetanus immunoglobulin derived from human or to other immunoglobulins.

HEART DISEASE

TETGLOB 250IU should be used with caution in patients with heart problems (such as high blood pressure). Therefore, consult your doctor before receiving it.

OTHERS

TETGLOB 250IU is not recommended for use if you:

  • have any blood clotting disorders (Ex. Factors N Lieden, Gullian Barre syndrome)

Before receiving TETGLOB 250IU inform your doctor if you:

  • have diabetes with problems in blood vessels
  • have low blood volume due to severe dehydration, diarrhoea, vomiting or blood loss
  • have to sit or lie still for a longer period (such as hospitalization)
  • have any kind of blood disorders (Ex. leukaemia, lymphoma)
  • have taken any vaccinations recently or scheduled for one in the upcoming days
  • are due to have any blood tests

Use in pediatrics:

TETGLOB 250IU can be used in children and adolescents (below 18 years) if prescribed by the physician. Therefore, consult your doctor before receiving it.  

Use in geriatrics:

TETGLOB 250IU can be used in elderly patients if prescribed by the physician. Therefore, consult your doctor before receiving it.

INTERACTIONS

A. Drug - Drug interactions:

Before receiving TETGLOB 250IU, inform your doctor if you are taking,

  • live viral vaccines such as measles, mumps, polio, and rubella

Overdosage:

TETGLOB 250IU will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unpleasant symptoms after receiving TETGLOB 250IU.

SYNOPSIS

Drug :   Tetanus immunoglobulin
Pharmacological Category :   Bacterial immunoglobulin
Therapeutic Indication :   Prevents and treats tetanus infection
Dosage Forms :   Injection

MORE INFORMATION

  • Keep TETGLOB 250IU out of reach of children
  • Store TETGLOB 250IU in a refrigerator (2-8°C)

FAQs ABOUT TETGLOB 250IU

What are the uses of TETGLOB 250IU?

TETGLOB 250IU is used to prevent tetanus infection following injuries in patients who are at risk of getting infected with tetanus causing germs. It can also be used in patients who did not receive tetanus vaccine over the last 10 years or in patients who don’t remember about their vaccination status. TETGLOB 250IU is also used in the treatment of active tetanus infection. It is always administered along with tetanus vaccine for improved effects.

What TETGLOB 250IU does to our body?

TETGLOB 250IU offers protection against tetanus causing germs by supplementing our body with sufficient antibodies that is required to fight against the infection. The immunoglobulins (antibodies) present in the medicine binds to the tetanus causing germs and prevents them from attacking the nervous system. As a result, TETGLOB 250IU prevents painful muscle spasms and other conditions associated with tetanus.

When can I take TETGLOB 250IU?

TETGLOB 250IU should be taken as soon as possible after an injury or an accident. Consult your doctor immediately if your injury is deeper or severe.

What is the difference between tetanus vaccine and TETGLOB 250IU?

TETGLOB 250IU contains tetanus immunoglobulin (antibodies) which is derived from blood of the screened donors. These immunoglobulin supplements our body with sufficient antibodies which are required to fight against the tetanus causing germs. Whereas Tetanus vaccine contains inactivated tetanus causing bacteria which stimulates our body to release protective antibodies against them and offers immunity.

How early we need to take TETGLOB 250IU after an injury?

TETGLOB 250IU should be taken as soon as possible after an injury or an accident. Consult your doctor immediately if your injury is deeper or severe.

Why TETGLOB 250IU causes mild fever?

TETGLOB 250IU offers immunity against tetanus causing germs by causing a mild infection. It supplements our body with sufficient antibodies that is required to fight against the infection. Following administration, the antibodies and germs binds together initiating an antigen-antibody reactions. This causes signs of infection such as mild fever or body pains. These side effects are usually mild and disappears within a few days. However, consult your doctor if they worsen.

How should TETGLOB 250IU be given?

TETGLOB 250IU will be given to you only by a doctor or nurse into the muscles (intramuscularly) of thighs or buttocks. Your doctor will decide the correct dose for you depending upon your age, body weight and severity of infection.

Can I use TETGLOB 250IU to treat tetanus?

Yes. TETGLOB 250IU is used to treat tetanus infection. It can also be used to prevent tetanus infection among patients who had a recent injury, irrespective of their vaccination status.

Who should not get TETGLOB 250IU?

Do not receive TETGLOB 250IU if you are allergic to tetanus immunoglobulin or other immunoglobulins. Before receiving TETGLOB 250IU inform your doctor if you are severely dehydrated or have diabetes, high blood pressure or blood clots in the body. You must also inform your doctor if you got vaccinated recently or scheduled for any upcoming vaccination.

Can I take TETGLOB 250IU during pregnancy?

Enough evidence is not available to provide clarity on the use of TETGLOB 250IU during pregnancy. However, if you are pregnant or planning to conceive, consult your doctor before receiving TETGLOB 250IU.

Can I take TETGLOB 250IU even if not vaccinated with tetanus vaccine?

Yes. TETGLOB 250IU can be used to prevent tetanus infection in patients who did not receive tetanus vaccine over the last 10 years or in patients who don’t remember about their vaccination status. However, consult your doctor before receiving TETGLOB 250IU.

Who needs TETGLOB 250IU?

TETGLOB 250IU is generally given to people who have a weak immune system or who cannot produce sufficient antibodies by their own. Also, it can be taken by people who met with sudden injury which is likely more prone to get infected with Clostridium tetani. TETGLOB 250IU only helps to boost your immunity and must be administered to injured patients, irrespective of their previous vaccination. However, repeated administration within a short duration is not recommended.

REFERENCES

1. Joseph. T. Dipiro. Vaccines, Toxoids, and Other Immunobiologics. Pharmacotherapy. A Pathophysiological Approach. Eleventh edition. Page – 2152.

2. Remi Forrat, Rafaele Dumas, Michael Seiberling, Michael Merz, Charles Lutsch and Jean Lang. Evaluation of the Safety and Pharmacokinetic Profile of a New, Pasteurized, Human Tetanus Immunoglobulin Administered as Sham, Postexposure Prophylaxis of Tetanus. NIH. National Library of Medicine. National Center for Biotechnology Information. PubMed Central. [Accessed on 23rd March 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC105404/

3. Bio Products Laboratory Limited, Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 21st June 2022] https://www.medicines.org.uk/emc/files/pil.5547.pdf

4. Grifols Therapeutic LLC.  [Revised in December 2020] [Accessed on 21st June 2022] https://dailymed.nlm.nih.gov/dailymed/getFile.cfm?setid=393fa198-7e07-4162-bd0a-9d873f1544a9&type=pdf

5. Human Tetanus Immunoglobulin (HTIG). Medicines Sans Frontieres. [Accessed on 2nd April 2022] https://medicalguidelines.msf.org/viewport/EssDr/english/human-tetanus-immunoglobulin-htig-16688425.html

6. Tejpratap S.P. Tiwari, MD; Pedro L. Moro, MD, MPH; and Anna M. Acosta, MD. Tetanus. CDC.gov. August 2021. [Accessed 30th March 2022] https://www.cdc.gov/vaccines/pubs/pinkbook/downloads/tetanus.pdf

7. MIMS. Human tetanus immunoglobulin. [Accessed on 23rd March 2022] https://www.mims.com/philippines/drug/info/tetagam%20p?type=full    

USEFUL DIAGNOSTIC TESTS

  • Complete blood count

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    20 g
    Ingredient
    TETANUS IMMUNOGLOBULIN 250 IU
    Hsn Code
    30029090
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