INTRODUCTION

TERFEXX MF CREAM is a combination of Mometasone and Terbinafine which belongs to the group of medicines called Topical corticosteroids and Antifungals, respectively. TERFEXX MF CREAM is used to treat fungal skin infections associated with inflammation and itching.

A fungal infection is a type of skin disease caused by a fungus which is a microorganism that invades the tissue and cause disease that's confined to the skin and spreads into tissue, bones, organs and other parts of the body with symptoms generally including skin rash or vaginal infection resulting in abnormal discharge.

Avoid using TERFEXX MF CREAM, if you have rosacea (a skin condition affecting the face), acne (pimples), skin atrophy (thinning of the skin), genital itching, nappy rash, shingles (viral infection), warts (type of skin infection) and ulcerated skin.

Before using TERFEXX MF CREAM, inform your doctor if you have psoriasis (itchy skin rash) or any other skin problems. This medicine is not recommended for use during pregnancy unless it is clearly advised by the doctor and it is not recommended for use in breastfeeding women.

TERFEXX MF CREAM is not recommended for use in children (aged below 12 years). The most common side effects of using TERFEXX MF CREAM are skin peeling and itching. Consult your doctor if any of the side effects get worse.

USES OF TERFEXX MF CREAM

• Treats fungal infection associated with inflammation and itching

HOW TERFEXX MF CREAM WORKS

TERFEXX MF CREAM is used to treat fungal skin infections, where mometasone reduces the redness and itchiness of skin by blocking the production of chemical messenger, prostaglandin which is responsible for causing redness and itchiness of skin and terbinafine causes destruction of fungi by forming holes in the cell membrane of fungi which results in the degradation of fungi cell thereby causing its destruction and providing relief from the infection.

DIRECTIONS FOR USE

Always apply TERFEXX MF CREAM as directed by your physician. It is for external use only. On the affected area, apply a thin layer of this medicine. Treated areas need not be covered with plaster or bandage. Your doctor will decide the duration and frequency of using this medicine depending upon severity of the infection.

SIDE EFFECTS OF TERFEXX MF CREAM

HOW TO MANAGE SIDE EFFECTS

Dry Skin:

Try moisturizing your skin with a lotion 2 to 3 times a day or as often needed. Moisturizers help to keep the area moisturized, so they work best on damp skin. After you take a bath, pat your skin dry then apply your moisturizer. Try to avoid using skin care products and soaps that contain alcohol, fragrances, dyes or other chemicals.

Skin itching:

Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Avoid sun exposure or UV rays as it may sensitize your skin. Use sunscreen and protective clothing when going outdoors. Regularly moisturize your skin after consulting the doctor. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions:

Before using TERFEXX MF CREAM, inform your doctor if you are using any medicines including prescription or non-prescription medicines

Overdosage:

If you or anyone else accidentally applied too much of TERFEXX MF CREAM, consult your doctor immediately or visit the nearby hospital. Symptoms of accidental ingestion include dizziness, nausea, headache and stomach pain.

SYNOPSIS

MORE INFORMATION

• Keep TERFEXX MF CREAM out of reach of children
• Store TERFEXX MF CREAM at room temperature

FAQs ABOUT TERFEXX MF CREAM

What is TERFEXX MF CREAM and why is it prescribed?

TERFEXX MF CREAM is a combination of Mometasone and Terbinafine which belongs to the group of medicines called Topical corticosteroids and Antifungals, respectively. TERFEXX MF CREAM is used to treat fungal skin infections associated with inflammation and itching.

What happens if you forget to use TERFEXX MF CREAM?

If you forget to apply TERFEXX MF CREAM then try to apply it as soon as you remember. If the time is for the next application then carry on as normal. Try to remember to apply TERFEXX MF CREAM as per its application time to avoid the risks of returning infection.

What happens if you suddenly stop using TERFEXX MF CREAM?

Do not stop using TERFEXX MF CREAM before the recommended time since the infection might be more likely to return. If you have any further queries on the use of this medicine, consult your doctor before stopping TERFEXX MF CREAM.

Who should avoid using TERFEXX MF CREAM?

TERFEXX MF CREAM is not recommended for use in patients with rosacea (a skin condition affecting the face), acne (pimples), skin atrophy (thinning of the skin), dermatitis (skin inflammation) around the mouth, genital itching, nappy rash, cold sores and viral infections such as shingles, chickenpox (viral infection). Consult your doctor before using TERFEXX MF CREAM.

Is TERFEXX MF CREAM safe to be used in pregnant and breastfeeding women?

TERFEXX MF CREAM is not recommended for use during pregnancy unless it is clearly advised by the doctor and it is not recommended for use in breastfeeding women. Consult your doctor before using TERFEXX MF CREAM.

REFERENCES

1. KD. Tripathi. Antifungal Drugs and Drugs Acting on Skin & Mucous Membranes. Essentials of medical pharmacology. Seventh edition. 2013. Page – 795 &  895

2. Libbs Farmacêutica LTDA. Comparative Study:Topison (Mometasone Furoate) Versus Two Others Mometasone Furoates (LB2001). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in June 2021] [Accessed on 21st May 2022] https://clinicaltrials.gov/ct2/show/NCT04271007

3. Fabrizio Spada, Tanya M Barnes, and Kerryn A Greive. Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. February 2018 [Accessed on 21st May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099284/

4. Luke Maxfield; Charles V. Preuss; Rene Bermudez. Terbinafine. NIH National Library of Medicine, National center for biotechnology information. March 2022 [Accessed on 21st May 2022] https://www.ncbi.nlm.nih.gov/books/NBK545218/

5. Fabrizio Spada, Tanya M Barnes, and Kerryn A Greive. Comparative safety and efficacy of topical mometasone furoate with other topical corticosteroids. NIH National Library of Medicine, National center for biotechnology information. PMC PubMed Central. February 2018 [Accessed on 21st May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099284/

6. Bethesda. Terbinafine. NIH National Library of Medicine, National center for biotechnology information. January 2018 [Accessed on 21st May 2022] https://www.ncbi.nlm.nih.gov/books/NBK548617/

7. Salutas Pharma GmbH. Electronic medicines compendium (EMC). [Revised in January 2022] [Accessed on 21st May 2022] https://www.medicines.org.uk/emc/files/pil.9996.pdf

8. Gerard Laboratories & Gedeon Richter Plc.  Electronic medicines compendium (EMC). [Revised in April 2019] [Accessed on 21st May 2022] https://www.medicines.org.uk/emc/files/pil.12831.pdf

USEFUL DIAGNOSTIC TESTS

• Complete blood count
• Fungal Culture Test