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INTRODUCTION
TAZLOC 40MG TABLET contains Telmisartan which belongs to the group of medicines called Angiotensin II receptor antagonists. It is used to treat essential hypertension in adults. High blood pressure that is not caused by any other condition is called as essential hypertension. It is characterized by symptoms such as early morning headaches, nosebleeds, irregular heartbeat, vision changes, buzzing in the ears, fatigue, nausea and chest pain.
It is also used to reduce the risk of cardiovascular events such as heart attack or stroke in adults who are known to have a reduced or blocked blood supply to the heart or legs and had a stroke or with a high risk of diabetes.
Your doctor may check your kidney function test, blood pressure and the amount of electrolytes (Ex. potassium) in your body prior to the treatment or at regular intervals during treatment with this medicine.
TAZLOC 40MG TABLET is not recommended for use in patients having severe liver problems such as cholestasis or biliary obstruction (flow of bile from liver stops or slows). TAZLOC 40MG TABLET should be used with caution in patients having diabetes, kidney disease, heart problems and raised aldosterone levels.
TAZLOC 40MG TABLET is not recommended for use in early pregnancy and must not be taken by women who are pregnant for more than 3 months and it is not recommended for use in breastfeeding women.
TAZLOC 40MG TABLET is not recommended for use in children and adolescents (up to the age of 18 years) and it should be used with caution in elderly patients (aged 65 years and above).
The most common side effect of taking TAZLOC 40MG TABLET is low blood pressure. Consult your doctor if the symptom worsens.
USES OF TAZLOC 40MG TABLET
- Treats essential hypertension (high blood pressure)
- Reduces the risk of cardiovascular events (such as stroke and heart attack)
HOW TAZLOC 40MG TABLET WORKS
TAZLOC 40MG TABLET makes blood vessels to relax and thus lowers the blood pressure by blocking the effects of Angiotensin II (substance produced in your body which causes narrowing of blood vessels).
DIRECTIONS FOR USE
Take TAZLOC 40MG TABLET as advised by your physician. Swallow this medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of TAZLOC 40MG TABLET for you depending upon your age, body weight and disease condition.
SIDE EFFECTS OF TAZLOC 40MG TABLET
COMMON
• low blood pressure
UNCOMMON
- urinary tract infection
- signs of upper respiratory tract infection (sore throat, inflamed sinuses, common cold)
- anemia, feeling of weakness
- insomnia, fainting
- feeling of spinning (vertigo)
- slow heart rate, chest pain
- dizziness on standing up (orthostatic hypotension)
- cough
- shortness of breath
- abdominal pain, abdominal discomfort, bloating
- diarrhea
- vomiting
- increased sweating
- drug rash, itching
- muscle cramps, muscle or back pain
RARE
- signs of low platelet count (easy bleeding or bruising)
- severe allergic reaction (anaphylactic reaction)
- allergic reaction (Ex. rash, itching, wheezing)
- low sugar level in blood (in diabetic patients)
- feeling anxious, sleepiness
- impaired vision
- fast heartbeat
- dry mouth, dysgeusia (impaired sense of taste)
- eczema (a skin condition with red, itchy, irritated skin)
- flu-like-illness
- severe drug rash, pain in joints, joint stiffness
Stop taking TAZLOC 40MG TABLET and contact your doctor immediately if you experience any of the following side effects:
- sepsis (body's life-threatening response to infection which can lead to death, organ failure)
- angioedema (rapid swelling of the skin and mucosa)
HOW TO MANAGE SIDE EFFECTS
Vomiting:
Take TAZLOC 40MG TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals. Consult your doctor if your symptom does not improve.
Diarrhea:
Drink lot of fluids such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own to treat without consulting your doctor.
Stomach pain:
Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, consult your doctor.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
WARNING & PRECAUTIONS
PREGNANCY
TAZLOC 40MG TABLET is not recommended in early pregnancy and must not be taken when more than 3 months pregnant, as it may cause serious harm to the baby if used after 3 months of pregnancy. Consult your doctor before taking TAZLOC 40MG TABLET.
BREASTFEEDING
TAZLOC 40MG TABLET is not recommended for use in breastfeeding women. Your doctor may choose another treatment especially if you want to breast-feed when your baby is new-born or born prematurely. Consult your doctor for advice before taking TAZLOC 40MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy or tired after taking TAZLOC 40MG TABLET. Consult your doctor before taking TAZLOC 40MG TABLET.
ALCOHOL
Avoid consumption of alcohol as it may increase the risk of low blood pressure.
KIDNEY
TAZLOC 40MG TABLET should be taken with caution in patients with kidney disease, kidney artery stenosis (narrowing of blood vessels to one or both the kidneys) and with a history of kidney transplant. Consult your doctor before taking TAZLOC 40MG TABLET.
LIVER
TAZLOC 40MG TABLET is not recommended for use in patients with severe liver problems such as cholestasis or biliary obstruction (flow of bile from liver stops or slows). TAZLOC 40MG TABLET should be used with caution in patients with liver diseases. Consult your doctor before taking TAZLOC 40MG TABLET.
ALLERGY
TAZLOC 40MG TABLET is not recommended for use if you are allergic to Telmisartan or any other ingredients of this medicine.
HEART DISEASE
TAZLOC 40MG TABLET should be taken with caution in patients having heart trouble or low blood pressure (due to dehydration problems, low-salt intake, diarrhoea or vomiting). Before taking TAZLOC 40MG TABLET consult with your doctor.
OTHERS
Before taking TAZLOC 40MG TABLET, inform your doctor if you have:
- high potassium levels in the body
- raised aldosterone levels (water and salt retention in the body along with imbalance of various blood minerals)
- diabetes
Use in pediatrics:
TAZLOC 40MG TABLET is not recommended for use in children and adolescents (under 18 years of age). Consult your child’s doctor for advice.
Use in geriatrics:
TAZLOC 40MG TABLET should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking this medicine.
INTERACTIONS
A. Drug - Drug interactions:
Before taking TAZLOC 40MG TABLET, inform your doctor if you are taking any of the following medicines:
- angiotensin converting enzyme inhibitors (Ex. enalapril, lisinopril, ramipril), angiotensin II receptor antagonists (Ex. candesartan, irbesartan) and aliskiren (medicines used to treat high blood pressure)
- digoxin (used to treat heart failure and abnormal heart rhythm)
- medicines containing lithium (used to treat some types of depression)
- medicines that may increase blood potassium levels such as salt substitutes containing potassium
- non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen (medicines used to treat pain and inflammation
- heparin (used to prevent or treat blood clot)
- immunosuppressive agents such as ciclosporin or tacrolimus (used to prevent organ rejection after transplant)
- antibiotic trimethoprim (medicine used to treat and prevent urinary tract infections)
- diuretics such as furosemide, hydrochlorothiazide and potassium-sparing diuretics (Ex. amiloride, spironolactone) (used to treat oedema or high blood pressure)
- corticosteroids such as dexamethasone, hydrocortisone (used to treat inflammatory conditions)
- baclofen (used for muscle spasm)
- amifostine (medicine used in cancer chemotherapy)
- barbiturates such as phenobarbital, pentobarbital (used to treat seizures)
- antidepressants such as citalopram, fluoxetine, paroxetine (used to treat depression)
- narcotics such as morphine and codeine (used to treat moderate to severe pain)
Overdosage:
If you or anyone else accidentally take too much of TAZLOC 40MG TABLET, consult your doctor immediately or visit the nearby hospital. The most common symptoms of overdose are low blood pressure, fast or slow heartbeat, dizziness, elevated levels of creatinine and sudden kidney failure.
SYNOPSIS
| Drug | : | Telmisartan |
| Pharmacological Category | : | Angiotensin receptor blockers |
| Therapeutic Indication | : | Essential hypertension, prevention of heart attack and stroke |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- keep TAZLOC 40MG TABLET out of reach of children
- Store at room temperature
FAQs ABOUT TAZLOC 40MG TABLET
Can TAZLOC 40MG TABLET be used to treat high blood pressure?
TAZLOC 40MG TABLET can be considered as a drug of choice for high blood pressure. It contains telmisartan which helps to relax the blood vessels and then normalize the blood pressure. Although, TAZLOC 40MG TABLET can treat high blood pressure, you doctor might treat you with other drugs depending upon your condition.
Can TAZLOC 40MG TABLET cause slow heart rate?
Yes, TAZLOC 40MG TABLET can make your heart to beat slow. If you experience any abnormally slow heart rate with shortness of breath, feeling of fainting and spinning sensation (vertigo) consult your doctor immediately.
What precautions do I need to follow while taking TAZLOC 40MG TABLET?
Patients taking TAZLOC 40MG TABLET must inform their doctor about their pre-existing disease conditions like kidney, heart or liver problems. Consult your doctor immediately if you experience any unusual symptoms after taking TAZLOC 40MG TABLET.
What happens if I stop taking TAZLOC 40MG TABLET?
Do not stop taking TAZLOC 40MG TABLET without talking to your doctor first. Stopping this medicine suddenly can cause your blood pressure to spike and may increase the risk for heart attack or stroke.
Is TAZLOC 40MG TABLET safe to use in patients with kidney problems?
TAZLOC 40MG TABLET should be taken with caution in patients with kidney disease, kidney artery stenosis (narrowing of blood vessels to one or both the kidneys) and with a history of kidney transplant. Your doctor may assess your kidney functioning during treatment with this medicine to prevent the risk of kidney damage or any unusual effects. Consult your doctor before taking TAZLOC 40MG TABLET.
How long should TAZLOC 40MG TABLET be taken?
TAZLOC 40MG TABLET does not cure high blood pressure but controls it. Your blood pressure may decrease during the first 2 weeks of treatment, but it may take 4 weeks for you to notice the full benefit of this medicine. Consult your doctor for the exact duration of recommendation for you.
REFERENCES
1. KD. Tripathi. Drugs Affecting Renin Angiotensin System. Essentials of medical pharmacology. Eighth edition. 2019. Page – 535-538.
2. Philippe Gosse. A Review of Telmisartan in the Treatment of Hypertension: Blood Pressure Control in the Early Morning Hours. NIH National Library of Medicine, National center for biotechnology information. PubMed Central. September 2006. [Accessed on 7th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1993985/
3. A Prem Kumar, Anirudra Ghorai, Vasudev Kriplani, Rabindra Kumar Dash, J Aravinda, Paramesh Shamanna, TK Sabeer, Abdul Hannan, and Santosh Revankar. Clinical data analysis of telmisartan for hypertension management in Indian population. NIH National Library of Medicine, National center for biotechnology information. PubMed Central June 2021. [Accessed on 7th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819792/
4. Accord Healthcare Ireland Limited. Health Products Regulatory Authority (HPRA). [Revised in July 2021] [Accessed on 7th May 2022] http://www.hpra.ie/img/uploaded/swedocuments/8c0fc811-cf88-4bd5-818e-609e07fe1190.pdf
5. Hetero Labs Limited. U.S. Food & Drug Administration. [Revised in August 2015] [Accessed 7th May 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/205901Orig1s000lbl.pdf
USEFUL DIAGNOSTIC TESTS
- Kidney function test
AUTHOR DETAILS
Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 12 Oct 2022 | 06:05 PM(IST)
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