Tacstead 1mg Capsule 10'S

Auto Immune Disease Rx required

Best Price*  ₹ 344.07
MRP ₹382.30
(Inclusive of all taxes) *10 Capsule(s) in a Strip * Mfr: Steadfast Medishield Pvt Ltd * Country of Origin: India
TOTAL AMOUNT ₹ 382.30

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INTRODUCTION

TACSTEAD 1MG contains Tacrolimus which belongs to the group of medicines called immunosuppressants. It is used with other medicines to help prevent organ rejection in adults who had a kidney, liver or heart transplant. Following an organ transplant, our immune system will try to reject the newly transplanted organ. Tacrolimus controls our body’s immune response and enables it to accept the transplanted organ.

It may also be given during an ongoing rejection of transplanted liver, kidney, heart or other organ, when previous treatment was unable to control your immune response. Tacrolimus acts by inhibiting the activity of T-lymphocytes and cytokines. While taking this medicine, your doctor might recommend you, to do blood test, urine test, heart and eye tests, to set the correct dose.

It should be taken orally on an empty stomach. Avoid drinking alcohol or grapefruit juice while taking this medicine. Limit your exposure to sun and UV light, because immunosuppressants could increase the risk of skin cancer. TACSTEAD 1MG must not be taken with cyclosporin. This medicine is not recommended in children and adolescents under 18 years of age.

USES OF TACSTEAD 1MG

  • Prophylaxis of organ rejection in adults with kidney, liver or heart transplants

HOW TACSTEAD 1MG WORKS

Tacrolimus prevents rejection by inhibiting T lymphocyte cells and cytokines, specific cells of the immune system. This in turn controls our body’s immune response and enables it to accept the transplanted organ.

DIRECTIONS FOR USE

Take this medicine on an empty stomach or 2 to 3 hours after a meal or as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF TACSTEAD 1MG

COMMON

  • diabetes mellitus
  • difficulty in sleeping
  • headache, dizziness
  • increased blood pressure
  • stomach pain, diarrhea, mouth ulcers, vomiting, constipation, bloating
  • anxiety, confusion, depression, mood changes, hallucination, mental disorders
  • fits, tingling and numbness in hands and feet
  • blurred vision, ringing in your ears
  • faster heartbeat, shortness of breath
  • inflammation of pharynx, cough
  • yellowing of skin
  • muscle pain, back pain, joint pain
  • impaired or painful urination
  • fever

RARE

  • small bleedings in skin due to blood clots
  • blindness, deafness
  • serious reactions with blistering of skin, mouth, eyes and genitals
  • increased hair growth
  • feeling thirsty

HOW TO MANAGE SIDE EFFECTS

Vomiting:

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.

Bloating:

Eat smaller and frequent meals. Eat and drink slowly, and exercise regularly. If the symptoms get worse, contact your doctor.

Constipation: 

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

WARNING & PRECAUTIONS

PREGNANCY

TACSTEAD 1MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

TACSTEAD 1MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machines if your ability is affected by this medicine.

ALCOHOL

Avoid consumption of alcohol or grape-fruit juice while taking this medicine.

LIVER

TACSTEAD 1MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic (hypersensitive) to tacrolimus, sirolimus, or to any macrolide-antibiotics.

HEART DISEASE

TACSTEAD 1MG should be taken with caution in patients with QT wave prolongation. Consult your doctor for advice.

OTHERS

Before taking this medicine, inform your doctor if you:

  • have severe diarrhea, stomach pain with or without chills, fever, nausea or vomiting, blurred vision or changes in color vision

INTERACTIONS

Talk to your doctor, if you are taking,

  • other immunosuppressant drugs (e.g. ciclosporin, mycophenolic acid)
  • medicines used to treat viral infections such as HIV (e.g. ritonavir, nelfinavir, saquinavir and cobicistat), hepatitis (telaprevir, boceprevir, ombitasvir, paritaprevir, dasabuvir), human cytomegalovirus (e.g. letermovir), herpes zoaster (e.g. acyclovir)
  • macrolide antibiotics (used to treat bacterial infections) e.g. erythromycin, clarithromycin, josamycin, amphotericin B and rifampicin
  • antifungal medicines (used to treat fungal infections) e.g. ketoconazole, fluconazole, itraconazole, voriconazole, clotrimazole and isavuconazole
  • medicines used to treat stomach ulcer and acid reflux (e.g. omeprazole, lansoprazole or cimetidine)
  • medicines used to treat nausea and vomiting (e.g. metoclopramide)
  • medicines used to treat heartburn (e.g. cisapride or aluminium-hydroxide)
  • medicines used to treat high blood pressure or heart problems (e.g. nifedipine, nicardipine, diltiazem, verapamil, amiodarone)
  • medicines used to treat elevated cholesterol and triglycerides (e.g. atorvastatin)
  • medicines used to treat depression (e.g. nefazodone, St. John’s Wort, or extracts of Schisandra sphenanthera)
  • nilotinib and imatinib (used to treat certain cancers)
  • contraceptive pill (birth control pills)
  • phenytoin or phenobarbital (used to treat epilepsy)
  • corticosteroids (used to treat inflammations) e.g. prednisolone and methylprednisolone
  • potassium supplements
  • diuretics (used to increase urine output) e.g. amiloride, triamterene, or spironolactone
  • non-steroidal anti-inflammatory drugs (NSAIDs, e.g. ibuprofen)
  • anticoagulants (used to thin blood) e.g. warfarin, heparin
  • oral medicines for diabetes (e.g. metformin)
  • vaccinations

SYNOPSIS

Drug :   Tacrolimus
Pharmacological Category :  

Immunosuppressants, Calcineurin Inhibitor

Therapeutic Indication :  

Prevents graft rejection

Dosage Forms :   Tablet, Capsule, Cream, Ointment, Lotion, Eye ointment, Topical solution

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT TACSTEAD 1MG

Can TACSTEAD 1MG used to treat vitiligo?

No. This medicine is intended only for the prophylaxis of graft rejection.

Can TACSTEAD 1MG used to treat acne?

No. This medicine is intended only for the prophylaxis of graft rejection.

Can TACSTEAD 1MG cause cancer?

Yes. Limit your exposure to sun and UV light, because immunosuppressants could increase the risk of skin cancer. Wear appropriate protective clothing and use a sunscreen with a high sun protection factor.

REFERENCES

1. KD Tripathi. Immunosuppressant drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 881.

2. Alan M. Krensky, William M. Bennett and Flavio Vincenti. Immunosuppressants, Tolerogens and Immunostimulants. Goodman & Gilman’s: The pharmacological basics of therapeutics. 12th Edition. New York, New York: McGraw-Hill Medical, 2011. Page – 1008-1009.

3. Astellas Pharma Inc. A Study of a Modified-Release Tacrolimus in Stable Pediatric Liver Transplant Patients Based Immunosuppression Regimen. NIH U.S. National library of medicine Clinical trials.gov. [Revised on October 2013] [Accessed 27th October 2020] https://clinicaltrials.gov/ct2/show/NCT00282256

4. David H. Peters, Andrew Fitton, Greg L. Plosker & Diana Faulds. Tacrolimus: A Review of its Pharmacology, and Therapeutic Potential in Hepatic and Renal Transplantation.  Springer Nature Switzerland AG. October 2012. [Accessed 27th October 2020] https://link.springer.com/article/10.2165%2F00003495-199346040-00009

5. Astellas Ireland Co., Ltd. [Revised on March 2020] [Accessed 26th October 2020] https://www.medicines.org.uk/emc/files/pil.7524.pdf

6. Astellas Pharma US, Inc. [Revised on February 2012] [Accessed 26th October 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf

Manufacturer/Marketer Details

    Net Qty
    1
    Shelf Life
    NA
    Item Weight
    17.5
    No. of Units in a Kit
    NA
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Tacstead 1mg Capsule 10'S

Tacstead 1mg Capsule 10'S Mfr: Steadfast Medishield Pvt Ltd

M.R.P.: Rs.382.30
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