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INTRODUCTION

SYLO contains a medicine called silymarin which belongs to the group of medicines called flavonoids. It is indicated as a supportive therapy for various chronic inflammatory disease of liver such as liver cirrhosis, viral hepatitis, alcoholic liver disease and drug-induced liver damage in adult patients. It can also be used to treat indigestion, lack of appetite and stomach upset caused due to overindulgence of food and drink in patients with liver problems. Silymarin is a flavonoid isolated from the plant species called Silybum marianum which is commonly known as milk thistle.

The antioxidant and hepatoprotective activities of silymarin effectively reduces the oxidative liver damage by inhibiting the generation of free radicals. Silymarin also enhances the cellular regeneration of hepatocytes by stimulating the activity of an enzyme called RNA polymerase I. It also improves metabolism and digestion by improving the overall functional capacity of the liver. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the disease.

Do not stop taking this medicine abruptly without consulting your doctor as it may worsen your existing condition. Avoid smoking and consumption of alcohol while taking this medicine. This medicine is generally safe and well tolerated. However, it may cause nausea, headache or indigestion in some individuals. Contact your doctor if any of the symptoms bothers you. SYLO is strictly not recommended for use in pregnant or lactating women and in children under 18 years of age. Consult your doctor before taking.

USES OF SYLO

  • Supportive therapy for various chronic inflammatory disease of liver such as liver cirrhosis, viral hepatitis, alcoholic liver disease and drug-induced liver damage in adult patients
  • Treats indigestion, lack of appetite and stomach upset in patients with liver problems

HOW SYLO WORKS

Silymarin is a flavonoid which contains both antioxidant and hepatoprotective properties. It effectively reduces the oxidative cellular damage of liver by inhibiting the generation of free radicals that are produced from the metabolism of toxic substances such as ethanol and carbon tetrachloride. It also enhances the regeneration of hepatocytes by stimulating the activity of an enzyme called RNA polymerase I and provides relief from various chronic inflammatory diseases of the liver. As a result, the overall functional capacity of liver is increased, which leads to an improvement in digestion, appetite and body weight.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and severity of the disease. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF SYLO

SERIOUS

  • allergic reactions such as (skin rash, itching, redness, difficulty in breathing, swelling of face, neck, tongue or throat)

COMMON

  • nausea
  • diarrhea
  • upset stomach
  • headache

HOW TO MANAGE SIDE EFFECTS

Nausea:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Headache:  

Rest and drink plenty of fluids. Do not drink too much alcohol. Ask your doctor to recommend a painkiller.

WARNING & PRECAUTIONS

PREGNANCY

SYLO is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

SYLO is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machines if your ability is affected by this medicine.

ALCOHOL

Avoid consumption of alcohol while taking this medicine.

LIVER

SYLO should be taken with caution in patients with severe liver problems. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to silymarin or other plants belonging to Asteraceae/Compositae family (e.g. daisies, artichokes, marigolds).

INTERACTIONS

Tell your doctor about all the medicines you use, including non-prescription and prescription medicines and herbal supplements.

SYNOPSIS

Drug :   Silymarin
Pharmacological Category :   Hepatoprotectant, Antioxidant, Flavonoids
Therapeutic Indication :   Liver disease, Cirrhosis, Indigestion
Dosage Forms :   Tablet, Syrup

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT SYLO

Is SYLO a vitamin?

No. This medicine is a flavonoid isolated from the plant species called Silybum marianum which is commonly known as milk thistle.

Is SYLO safe during pregnancy?

No. This medicine is strictly not recommended for use in pregnant women. Consult your doctor before taking.

Can SYLO cure fatty liver?

Yes. This medicine can be used to treat non-alcoholic fatty liver disease. However, your doctor will decide the correct dose and duration for you depending upon your health condition.

Can I take SYLO while breastfeeding?

No. This medicine is strictly not recommended for use in breastfeeding mothers. Consult your doctor before taking.

REFERENCES

1. Harsh Mohan. The liver, Biliary tract and Exocrine pancreas. Textbook of Pathology. 6th Edition. Page – 604-630.

2. University of Malaya. Silymarin for the Treatment of Non-Alcoholic Fatty Liver Disease (NAFLD). NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on January 2016] [Accessed 27th January 2021] https://clinicaltrials.gov/ct2/show/NCT02006498

3. Hassan Solhi, Ramin Ghahremani, Amir Mohammad Kazemifar and Zahra Hoseini Yazdi. Silymarin in treatment of non-alcoholic steatohepatitis: A randomized clinical trial. NCBI; PMC US National Library of Medicine, National Institute of Health. 2014. [Accessed 27th January 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894463/

4. Nancy Vargas-Mendoza, Eduardo Madrigal-Santillán, Ángel Morales-González, Jaime Esquivel-Soto, Cesar Esquivel-Chirino, Manuel García-Luna y González-Rubio, Juan A Gayosso-de-Lucio, and José A Morales-González. Hepatoprotective effect of silymarin. NCBI; PMC US National Library of Medicine, National Institute of Health. March 2014. [Accessed 27th January 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959115/#:~:text=Silymarin%20has%20both%20hepatoprotective%20and,hepatocyte%20external%20cell%20membrane%20modification.

5. Micro Labs Limited. Silybon. [Accessed 27th January 2021] https://www.microlabsltd.com/products

6. Serum Institute of India Pvt. Ltd. Limarin capsules and suspension (Silymarin capsules and suspension). [Accessed 27th January 2021] https://www.seruminstitute.com/product_ind_limarin.php

USEFUL DIAGNOSTIC TESTS

  • Liver function test

PRODUCT DETAILS

    Hsn Code
    30049099
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