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INTRODUCTION
SUPIROCIN B PLUS OINTMENT is a combination of Beclomethasone and Mupirocin, which belong to the groups of medicines called Anti-inflammatory and Antibiotic, respectively. It is used to treat bacterial skin infections like impetigo. Bacterial skin infections develop when bacteria enter through hair follicles or through small breaks in the skin that result from scrapes, surgery, punctures, sunburn, burns, animal or insect bites, wounds, and preexisting skin disorders.
Before using SUPIROCIN B PLUS OINTMENT, inform your doctor if you have psoriasis. SUPIROCIN B PLUS OINTMENT is not recommended for use in pregnant or breastfeeding women. Caution should be taken while using SUPIROCIN B PLUS OINTMENT unless considered necessary.
SUPIROCIN B PLUS OINTMENT is not recommended for children under the age of one. The most common side effects of this medicine are application site reactions such as burning, irritation, itching, and redness. Contact your physician if any of the above symptoms worsen.
USES OF SUPIROCIN B PLUS OINTMENT
- Treats bacterial skin infections like impetigo
HOW SUPIROCIN B PLUS OINTMENT WORKS
SUPIROCIN B PLUS OINTMENT is a combination of Beclomethasone and Mupirocin. Beclomethasone is a corticosteroid that is present in SUPIROCIN B PLUS OINTMENT and works by reducing inflammation and relieving symptoms like itching, redness, irritation, and swelling by blocking the enzymes responsible for causing them (prostaglandins and leukotrienes). Mupirocin, which is an antibacterial agent, exerts its action by reversibly binding to an enzyme (isoleucyl transfer RNA synthetase) and inhibiting its activity of synthesising proteins in the bacteria, producing microbicidal action.
DIRECTIONS FOR USE
Apply SUPIROCIN B PLUS OINTMENT as directed by your physician. It is for external use only. Cleanse and dry the skin to be treated. Wash your hands with soap and water, apply a thin layer of the medicine to the affected area of the skin, and rub it gently. Avoid contact with the eyes, nose, mouth, or inside the vagina. Do not cover, wrap, or bandage the skin unless directed by the doctor.
SIDE EFFECTS OF SUPIROCIN B PLUS OINTMENT
COMMON
- reaction at the site of application (like burning, irritation, itching, and redness)
- dryness and redness of the skin
RARE
Stop applying SUPIROCIN B PLUS OINTMENT and contact your physician immediately if you experience any of the following side effects:
- severe skin reactions or allergies (symptoms include raised and itchy rash, swelling, sometimes of the face or mouth, causing difficulty in breathing and collapse or loss of consciousness)
- skin problem gets worse
HOW TO MANAGE SIDE EFFECTS
Itchy skin:
Avoid taking hot baths because hot water can irritate the skin. Do not scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if the itching worsens.
WARNING & PRECAUTIONS
PREGNANCY
SUPIROCIN B PLUS OINTMENT should not be used in pregnancy unless considered necessary. Contact your doctor before applying it.
BREASTFEEDING
SUPIROCIN B PLUS OINTMENT should be used with caution in breastfeeding women as it is not known whether it may pass through breast milk. Contact your doctor before applying it.
ALLERGY
Do not apply SUPIROCIN B PLUS OINTMENT if you are allergic to Beclomethasone, Mupirocin, other corticosteroids, or other ingredients of this medicine.
OTHERS
SUPIROCIN B PLUS OINTMENT is not recommended for use if you have:
- acne
- severe reddening of the skin on and around the nose (rosacea)
- spotted red rash around the mouth (perioral dermatitis)
- itching around the back passage or private parts
- viral infections (like chickenpox, cold sores, or herpes)
- fungal infections (like athlete’s foot, thrush, or ringworm)
- skin blisters or sores that are caused by an infection
- varicose ulcers (ulcers which are caused by swollen veins)
- stasis ulcers (ulcers caused by reduced blood or flow of body fluid)
Before taking SUPIROCIN B PLUS OINTMENT, inform your doctor if you have:
- psoriasis
- applying for the medicine under an airtight dressing, including a child's nappy
- had or going to have BCG immunization vaccine
Use in pediatrics:
SUPIROCIN B PLUS OINTMENT is not recommended for use in children under 1-year-old. Contact your doctor before using.
Use in geriatrics:
In elderly patients, SUPIROCIN B PLUS OINTMENT should be used with caution. Contact your doctor before using.
INTERACTIONS
A. Drug-Drug interactions:
Before taking SUPIROCIN B PLUS OINTMENT, inform your doctor if you are taking any of the following medicine:
- medicine used to treat blood pressure (Ex. amlodipine)
- medicine used for medical termination of pregnancy (Ex. mifepristone)
- medicine used to thin the blood (Ex. warfarin)
- medicine used to prevent pregnancy (Ex. ethinyl estradiol)
- medicine used to treat diabetes (Ex. insulin)
- medicine used as an antibiotic (Ex. ciprofloxacin)
Overdosage:
If you or anyone else accidentally use too much of SUPIROCIN B PLUS OINTMENT or if you or a child accidentally swallow the medicine, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Beclomethasone, Mupirocin |
| Pharmacological Category | : | Anti-inflammatory, Antibiotic |
| Therapeutic Indication | : | Bacterial Infections |
| Dosage Forms | : | Ointment |
MORE INFORMATION
- Keep out of reach from children
- Store SUPIROCIN B PLUS OINTMENT below 25°C
FAQs ABOUT SUPIROCIN B PLUS OINTMENT
When is caution to be taken while using SUPIROCIN B PLUS OINTMENT?
Before taking SUPIROCIN B PLUS OINTMENT, inform your doctor if you have psoriasis, have to apply the medicine under an airtight dressing, including a child's nappy, or have had or are going to have the BCG immunisation vaccine. Consult your doctor before using SUPIROCIN B PLUS OINTMENT.
Is it safe for children to use SUPIROCIN B PLUS OINTMENT?
SUPIROCIN B PLUS OINTMENT is not recommended for children under the age of one. Contact your doctor before using SUPIROCIN B PLUS OINTMENT.
What are the common side effects of SUPIROCIN B PLUS OINTMENT?
The most common side effects of SUPIROCIN B PLUS OINTMENT are application-site reactions such as burning, irritation, itching, and redness. Contact your physician if any of the side effects persist or worsen.
How to use SUPIROCIN B PLUS OINTMENT
Apply SUPIROCIN B PLUS OINTMENT as directed by your physician. It is for external use only. Cleanse and dry the skin to be treated. Wash your hands with soap and water, apply a thin layer of the medicine to the affected area of the skin, and rub it gently. Avoid contact with the eyes, nose, mouth, or inside the vagina. Do not cover, wrap, or bandage the skin unless directed by the doctor.
What is the purpose of the SUPIROCIN B PLUS OINTMENT?
SUPIROCIN B PLUS OINTMENT is used to treat bacterial skin infections like impetigo. Bacterial skin infections develop when bacteria enter through hair follicles or through small breaks in the skin that result from scrapes, surgery, punctures, sunburn, burns, animal or insect bites, wounds, and pre-existing skin disorders.
REFERENCES
1. KD Tripathi. Corticosteroids, Antifungal drugs & Aminoglycoside Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 289,792, 750.
2. Bethesda (MD). Beclomethasone. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 30th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/20469
3. Bethesda (MD). Mupirocin. National Institute of Health. NLM. National Centre for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 30th June 2022] https://pubchem.ncbi.nlm.nih.gov/compound/446596
4. Srinivas Sidgiddi, MD, Refika I. Pakunlu, PhD, and Kent Allenby, MD. Efficacy, Safety, and Potency of Betamethasone Dipropionate Spray 0.05%. The Journal of Clinical and Aesthetic Dermatology. April 2018 (Accessed on 30th June 2022) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891082/
5. John Gisby and Joanna Bryant. Efficacy of a New Cream Formulation of Mupirocin: Comparison with Oral and Topical Agents in Experimental Skin Infections. Journal of Antimicrobial Agents and Chemotherapy. February 2000. [Accessed on 30th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC89667/
6. Beclomethasone and Mupirocin. www.lanternmeds.com. [Accessed on 30th June 2022] https://www.lanternmeds.com/supirocin-b-plus-ointment.html
7. Beclomethasone and Mupirocin. www.lyflink.com. [Accessed on 30th June 2022] https://www.lyflink.com/medicine/102616-supirocin-b-plus-ointment/
8. GlaxoSmithKline Pharmaceuticals. Electronic Medicines Compendium (EMC). [Revised in September 2021] [Accessed on 30th June 2022] https://www.medicines.org.uk/emc/files/pil.3812.pdf
9. Essential Generics. Medicines Compendium (EMC). [Revised in September 2021] [Accessed on 30th June 2022] https://www.medicines.org.uk/emc/files/pil.12941.pdf
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