INTRODUCTION

STALROX 150 TABLET contains Roxithromycin which belongs to the group of medicines called Antibiotics. It is used to treat mild to moderately severe bacterial infections such as upper respiratory tract infections like acute pharyngitis, sinusitis, tonsillitis, lower respiratory tract infections like acute exacerbations of chronic bronchitis and acute bronchitis (inflammation of bronchial tube with thick mucus and breathing difficulties, community acquired pneumonia (lung infection acquired outside the hospital), skin and soft issues infections, impetigo (contagious skin infections with red sores around the face, mouth and nose), non gonococcal urethritis (inflammation of urinary tube causing pain and burning sensation while urinating), acute pharyngitis, and tonsillitis (inflammation of tonsils or pharynx with sore throat and pain during swallowing).

Prior to the treatment with STALROX 150 TABLET, your doctor may want you to take several blood tests to understand your existing condition.

STALROX 150 TABLET is not recommended for patients having severely impaired liver function. Consult your doctor before taking the medicine.

It should be used with caution among patients with impaired kidney function and heart disease like congenital prolonged QT interval. Consult your doctor before taking STALROX 150 TABLET.

The safety and efficacy of [GBNKEYOWORD] has not been established in foetus (unborn child). Hence consult your doctor during pregnancy.

STALROX 150 TABLET is not recommended for use during breastfeeding as it may excrete in breastmilk. Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition.

Caution should be exercised when STALROX 150 TABLET is taken by elderly patients. The most common side effects of taking STALROX 150 TABLET are diarrhoea, nausea, vomiting, abdominal or stomach pain. Consult your doctor if any of the above side effects worsen or persist for a longer duration.

USES OF STALROX 150 TABLET

It is used treat bacterial infections such as:

• upper respiratory tract infections like acute pharyngitis, sinusitis, tonsillitis
• lower respiratory tract infections like acute exacerbations of chronic bronchitis and acute bronchitis, community acquired pneumonia
• skin and soft issues infections, impetigo (contagious skin infections)
• non gonococcal urethritis
• acute pharyngitis
• acute tonsillitis

HOW STALROX 150 TABLET WORKS

STALROX 150 TABLET works by inhibiting the protein synthesis through cell wall penetration of the suspectable organisms and binding on the 50 S ribosomal subunit of bacteria thereby terminating the bacterial growth. As a result, it blocks the growth of the bacteria and stops the infection from spreading.

DIRECTIONS FOR USE

Always take STALROX 150 TABLET as advised by your physician. Swallow the medicine with a glass of water before food or on an empty stomach (more than 3 hours after a meal). Do not chew or crush the medicine. Your doctor will decide the correct dose for you depending upon the age, body weight and severity of the infection.

SIDE EFFECTS OF STALROX 150 TABLET

HOW TO MANAGE SIDE EFFECTS

Diarrhea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

Nausea or Vomiting:

Stick to simple meals. Try to avoid oil rich or spicy foods, sugary snacks, and drinks. Try to drink liquid slowly along with your meals, or in between meals. Consult your doctor if your symptom is not improving.

Headache:

Apply hot or cold-water bag on your head. Try to take rest in a quiet and dark room. Drink tea or coffee. Massage on scalp or head with mild pressure. Consult your doctor for advice.

Stomach pain:

Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad on your stomach. Take your physician’s advice.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking STALROX 150 TABLET, inform your doctor if you are taking any of the following medicine:

• theophylline (medicine used to treat asthma)
• ergotamine or dihydroergotamine (used to treat migraine headache)
• terfenadine, astemizole (medicines used to treat allergic conditions)
• cisapride (used to treat heartburns and gastrointestinal problems)
• pimozide (used to treat psychosis)
• warfarin, vitamin K Antagonists like phenprocoumon (used to prevent blood clots)
• digoxin, digitoxin (medicines used to treat heart failure, irregular heart rhythms)
• midazolam (used to induce drowsiness or sleep before operations)
• ciclosporin (medicine used to prevent graft rejection after organ transplantation)
• chloroquine or hydroxychloroquine (used to treat malaria)
• rifabutin and bromocriptine (used in the treatment of HIV infections)

Overdosage:

If you or anyone else accidentally takes too much of STALROX 150 TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep STALROX 150 TABLET out of reach of children
• Store STALROX 150 TABLET at room temperature

FAQs ABOUT STALROX 150 TABLET

What is the use of STALROX 150 TABLET?

STALROX 150 TABLET treats bacterial infections such as upper respiratory tract infections like acute pharyngitis, sinusitis, tonsillitis, lower respiratory tract infections like acute exacerbations of chronic bronchitis and acute bronchitis, community acquired pneumonia, skin and soft issues infections, impetigo (contagious skin infections), non gonococcal urethritis, acute pharyngitis, and acute tonsillitis.

When should I take STALROX 150 TABLET?

Always take as advised by your physician. STALROX 150 TABLET should be taken at least 15 minutes before food or on an empty stomach (3 hours after a meal). Swallow the medicine with a glass of water and do not chew or crush the medicine.

Can STALROX 150 TABLET be used in breast-feeding woman?

STALROX 150 TABLET is not recommended for use during breastfeeding since it is excreted in breastmilk. Consult your doctor for advice.

Does STALROX 150 TABLET cause diarrhoea?

Diarrhoea is a common side effect caused while taking antibiotics. It will resolve on its own once the medicine course terminates. Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

Who should avoid taking STALROX 150 TABLET?

STALROX 150 TABLET is not recommended for patients having severely impaired liver function. Consult your doctor before taking STALROX 150 TABLET.

How long I should use STALROX 150 TABLET?

STALROX 150 TABLET should be used as long as per your physician’s advice. Prolonged use of this medicine or other antibiotics may cause superinfection which occurs additionally over the existing infection.

REFERENCES

1. KD. Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Anti bacteria Antibiotics; Urinary Antiseptics. Essentials of medical pharmacology. Eighth edition. 2019. Page –805.

2. Roxithromycin. NIH National Library of Medicine, National Centre for biotechnology information. PubChem. October 2022. [Accessed 29th October 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Roxithromycin

3. J.K. Aronson. ScienceDirect. Roxithromycin. 2016. [Accessed 29th October 2022] https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/roxithromycin

4. Sanofi-Aventis Australia Private Ltd. RULIDE & RULIDE D (ROXITHROMYCIN). [Revised in October 2022] [Accessed 29th October 2022] https://secure.guildlink.com.au/gc/ws/sw/pi.cfm?product=swprulid

5. Teva Pharma (New Zealand) Limited. ARROW – ROXITHROMYCIN. [Revised in May 2017] [Accessed 29th October 2022] https://www.medsafe.govt.nz/Consumers/cmi/a/arrow-roxithromycin.pdf

6. DM PHARMA. Roxithromycin tablet. [Accessed 29th October 2022] http://dmpharma.co.in/ROXYDM.ht

USEFUL DIAGNOSTIC TESTS

• Complete blood count