SPRINTAS 100mg Capsule 5's

Auto Immune Disease Rx required

Best Price*  ₹ 431.55
MRP ₹539.44
(Inclusive of all taxes) *5 Capsule(s) in a Strip * Mkt: Intas Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

SPRINTAS 100MG contains Cyclosporin which belongs to the group of medicines called immunosuppressive agents. Immunosuppressive agents are the drugs that suppress or reduces the strength of body’s immune system. It is used to prevent graft rejection in patients who have had an organ transplant, bone marrow and stem cell transplantation.

It can also be used to treat various autoimmune disease like severe rheumatoid arthritis, nephrotic syndrome (kidney disease), eye problems (endogenous uveitis, including Behçet's uveitis) and skin diseases (atopic dermatitis, or eczema and psoriasis). Cyclosporin blocks the development of cells which attack the affected transplanted tissue and suppress abnormal immune function thus preventing the rejection of transplanted organs.

Limit your exposure to sunlight and UV light by wearing protective clothing and by applying a sunscreen to prevent skin cancer. Avoid consumption of alcohol or grapefruit juice while taking this medicine. This medicine should not be given to children for any non-transplant disease, except for nephrotic syndrome. Do not take this medicine if you have any uncontrollable infection or any type of cancer. Consult your doctor for advice.

USES OF SPRINTAS 100MG

  • Prevents the rejection of transplanted organs
  • Treats severe rheumatoid arthritis
  • Treats nephrotic syndrome (kidney disease)
  • Treats eye problems such as endogenous uveitis, including Behçet's uveitis
  • Treats skin diseases such as atopic dermatitis, or eczema and psoriasis)

HOW SPRINTAS 100MG WORKS

Cyclosporin works by inhibiting the production of various cytokines involved in the regulation of T-cell activation. These effects of cyclosporine on T cells and on connective tissue cells can produce a range of cytokines. These in turn promote antibody (Ab) secreting plasma cells which finally bind and inactivate the antigen.

DIRECTIONS FOR USE

Take this medicine as directed by your physician. Your doctor will decide the correct dose for you depending upon your condition. Avoid drinking grapefruit juice while taking this medicine.

SIDE EFFECTS OF SPRINTAS 100MG

SERIOUS

  • fever or sore throat
  • signs of brain infection (e.g. changes in sight, loss of coordination, memory loss, difficulty in speaking, muscle weakness)
  • confusion
  • feeling disorientated
  • feeling agitated, sleeplessness
  • coma, paralysis
  • stiff neck
  • swelling at the back of eye
  • yellowing of skin and eyes
  • loss of appetite
  • dark colored urine
  • problems in urination
  • pale skin, feeling tired
  • bruising or bleeding

COMMON

  • high blood pressure
  • headache
  • tremor of your body
  • unwanted growth of body and facial hair
  • fits (seizures)
  • tiredness, loss of appetite
  • nausea, vomiting, abdominal pain, constipation, diarrhea
  • acne, hot flushes
  • fever
  • feeling numb or tingling
  • muscle pain
  • overgrowth of gum tissue

RARE

  • numbness or tingling in fingers and toes
  • severe upper stomach pain
  • swelling of face, stomach, hands and/or feet
  • chest pain
  • changes in menstrual cycle
  • breast enlargement in men

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.

Constipation: 

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Diarrhea:

Drink lots of fluids to avoid dehydration. Avoid taking any medicines for diarrhoea without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.

WARNING & PRECAUTIONS

PREGNANCY

SPRINTAS 100MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.

BREASTFEEDING

SPRINTAS 100MG should be used with caution in breast feeding women. Consult your doctor before taking this medicine.

DRIVING AND USING MACHINES

Avoid driving or operating any machines, if your ability is affected by this medicine.

ALCOHOL

Avoid consumption of alcohol while taking this medicine, as it may increase the risk of side effects.

KIDNEY

Do not take SPRINTAS 100MG if you are suffering from severe kidney disease. Consult your doctor for advice.

LIVER

SPRINTAS 100MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to cyclosporin.

HEART DISEASE

Do not take SPRINTAS 100MG if you are suffering from uncontrollable high blood pressure. Consult your doctor for advice.

OTHERS

Do not take this medicine, if you have:

  • any uncontrollable infection or any type of cancer
  • gout, alcohol-related problems or epilepsy, low blood magnesium levels, high blood potassium levels, or if you need to have a vaccination

INTERACTIONS

Talk to your doctor, if you are taking,

  • medicines that affects your potassium levels (e.g. spironolactone, aldosterone)
  • medicines used for heart problems or high blood pressure (e.g. diltiazem, nicardipine, verapamil, amiodarone, nifedipine or digoxin)
  • medicines used to treat epilepsy (e.g. carbamazepine or phenytoin)
  • medicines used to treat HIV (e.g. saquinavir, indinavir, ritonavir)
  • antibiotics (used to treat infections) e.g. erythromycin, gentamycin, tobramycin, ciprofloxacin
  • anti-fungal agents (used to treat fungal infection) e.g. voriconazole, terbinafine, amphotericin B)
  • cholic acid and derivatives (used to treat gallstones)
  • telaprevir (used to treat hepatitis C).
  • barbiturates (used to induce sleep)
  • octreotide (used to treat acromegaly)
  • orlistat (used to help weight loss)
  • St. John’s wort (used to treat depression)
  • ticlopidine (used after a stroke)
  • repaglinide (oral anti-diabetic medicine)
  • ambrisentan (used to treat pulmonary arterial hypertension)

SYNOPSIS

Drug :   Cyclosporin
Pharmacological Category :   Immunosuppressive agent, Calcineurin inhibitor
Therapeutic Indication :   Prevents graft rejection, Treats auto immune disease
Dosage Forms :  

Capsule, Oral suspension, Eye drops, Injection

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT SPRINTAS 100MG

Can SPRINTAS 100MG cause cancer?

Yes. This medicine increases your risk of developing cancers, particularly of the skin and lymphoid system. Limit your exposure to sunlight and UV light by wearing appropriate protective clothing and applying a sunscreen with a high protection factor often while taking this medicine.

Can SPRINTAS 100MG cause unwanted hair growth?

Yes. The common side effects of this medicine is excessive growth of body and facial hair However, if you experience any unusual symptoms, contact your physician.

REFERENCES

1. KD Tripathi. Immunosuppressant drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 878-881.

2. Alan M. Krensky, William M. Bennett and Flavio Vincenti. Immunosuppressants, Tolerogens and Immunostimulants. Goodman & Gilman’s: The pharmacological basics of therapeutics. 12th Edition. New York, New York: McGraw-Hill Medical, 2011. Page – 1009-1012.

3. Russian Academy of Medical Sciences. Study Cyclosporine (CsA) Versus Tacrolimus (Tacro) After Campath Induction in Kidney Transplantation (RSCS-Campath). NIH U.S. National library of medicine Clinical trials.gov. May 2016 [Accessed 26th October 2020] https://clinicaltrials.gov/ct2/show/NCT01346397

4. University Hospital. Cyclosporine A Pretreatment and Kidney Graft Function (Cys-A-Rein). NIH U.S. National library of medicine Clinical trials.gov. 20th September 2020. [Accessed 26th October 2020] https://clinicaltrials.gov/ct2/show/NCT02907554

5. Karl Stonecipher. Innovative Medical. Efficacy of Cyclosporine for the Prevention and Treatment of Dry Eye Symptoms Following LASIK or Photorefractive Keratectomy. NIH U.S. National library of medicine Clinical trials.gov. September 2008. [Accessed 26th October 2020] https://clinicaltrials.gov/ct2/show/NCT00349440

6. G Wells, D Haguenauer, B Shea, M E Suarez-Almazor, V A Welch, P Tugwell. Cyclosporine for rheumatoid arthritis. NIH: National Library of Medicine, National center of biotechnology Information Pubmed.gov. 2000. [Accessed 26th October 2020] https://pubmed.ncbi.nlm.nih.gov/10796412/

7. Novartis Pharmaceuticals. Verification Study of Ciclosporin for Atopic Dermatitis. NIH U.S. National library of medicine Clinical trials.gov. November 2011. [Accessed 26th October 2020] https://clinicaltrials.gov/ct2/show/NCT00232076

8. Dustin Tedesco and Lukas Haragsim. Cyclosporine: A Review. NCBI; PMC US National Library of Medicine, National Institute of Health. January 2012. [Accessed 27th October 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259474/

9. Novartis Pharmaceuticals UK Limited. Electronic Medicines Compendium (EMC); [Revised on March 2020] [Accessed 26th October 2020] https://www.medicines.org.uk/emc/files/pil.1034.pdf

USEFUL DIAGNOSTIC TESTS

  • Rheumatoid Factor - Agglutination
  • Rheumatoid Factor - Turbidometry
  • Rheumatoid Factor IgG Antibody

PRODUCT DETAILS

    Net Qty
    1
    Ingredient
    CYCLOSPORIN 100 mg
    Hsn Code
    30045039
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

SPRINTAS 100mg Capsule 5's

SPRINTAS 100mg Capsule 5's Mkt: Intas Pharmaceuticals Ltd

M.R.P.: Rs.539.44
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