SPENTRON 1mg Tablet 4's

Vomitting/Emesis Rx required
OUT OF STOCK

Best Price* ₹ 72.00 MRP ₹ 90.00
(Inclusive of all taxes) *4 Tablet(s) in a Strip * Mkt: Swati Spentose Pvt Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout



INTRODUCTION

SPENTRON 1MG TABLET contains a medicine Granisetron which belongs to a group of medicines called Anti-emetics. It is used to prevent or treat nausea (feeling sick) and vomiting (being sick) caused by other medical treatments such as chemotherapy or radiation treatment for cancer.

Before taking SPENTRON 1MG TABLET inform your doctor if you have heart diseases, blockage in your stomach or intestines, electrolyte abnormalities, galactose intolerance, lactase deficiency or glucose-galactose malabsorption.

SPENTRON 1MG TABLET is not recommended for use in pregnant and breast-feeding women. Consult with your doctor before taking. SPENTRON 1MG TABLET should not be used in children below 2 years of age. SPENTRON 1MG TABLET can be used in elderly people (65 years and older). However, consult with your doctor before taking.

The most common side effects are headache, constipation, problems sleeping (insomnia), and diarrhoea. Consult with your doctor if any of these worsen or doesn’t improve.

USES OF SPENTRON 1MG TABLET

Prevents or treats,

  • nausea and vomiting caused chemotherapy or radiotherapy

HOW SPENTRON 1MG TABLET WORKS

SPENTRON 1MG TABLET acts by inhibiting a receptor called 5-HT3 receptors present which present both in brain and gastrointestinal tract. This inhibition of 5-HT3 receptors in turn inhibits the stimulation of the vomiting centre, preventing nausea and vomiting.

DIRECTIONS FOR USE

Always take SPENTRON 1MG TABLET as directed by your physician. Swallow the medicine as a whole with a plenty of water and do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your conditions.

SIDE EFFECTS OF SPENTRON 1MG TABLET

COMMON

  • headache
  • constipation
  • problems sleeping (insomnia)
  • changes in liver function tests (pain in abdomen, nausea, vomiting, jaundice)
  • diarrhoea

RARE

Stop taking SPENTRON 1MG TABLET and inform your doctor immediately if you experience any of the following side effects:

  • changes in the heartbeat, chest pain, irregular heartbeat and changes seen on ECG readings (electrical recordings of the heart)
  • swelling of the hands, feet, ankles, face, lips and mouth or throat, which may cause difficulty in swallowing or breathing
  • rash or itching
  • fainting
  • serotonin syndrome symptoms such as diarrheoa, nausea, vomiting, high temperature and blood pressure, excessive sweating and rapid heartbeat, agitation, confusion, hallucination, shivering, muscles shakes, jerks or stiffness, loss of coordination and restlessness

HOW TO MANAGE SIDE EFFECTS

Diarrhoea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. Ask for your doctor’s advice if diarrhoea doesn’t improve.

Headache:

Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if headache doesn’t improve.

Constipation:

Eat plenty of fiber rich foods such as vegetables, fresh fruits, and cereals and drink plenty of water. Exercise more regularly. Ask for your doctor’s advice if constipation doesn’t improve.

WARNING & PRECAUTIONS

PREGNANCY

SPENTRON 1MG TABLET is not recommended for use in pregnant women. Consult your doctor before taking it.

BREASTFEEDING

SPENTRON 1MG TABLET is not recommended for use in breastfeeding women. Consult your doctor before taking it.

DRIVING AND USING MACHINES

SPENTRON 1MG TABLET should not affect your ability to drive or operate machinery.

ALLERGY

Do not take SPENTRON 1MG TABLET if you are allergic (hypersensitive) to Granisetron or any other ingredients of this medicine.

HEART DISEASE

SPENTRON 1MG TABLET should be used with caution in patients suffering from heart diseases. Consult your doctor for advice before taking SPENTRON 1MG TABLET.

OTHERS

Before taking SPENTRON 1MG TABLET, inform your doctor if you have:

  • blockage in the intestine (stomach-ache, wind, feeling or being sick, or difficulty passing stools)
  • electrolyte abnormalities (potassium, sodium, or calcium)
  • serotonin syndrome
  • been or are being treated for cancer with a medicine that might cause damage your heart
  • lactose intolerance

Use in pediatrics:

SPENTRON 1MG TABLET is not recommended for use in children below 2 years of age. Consult with your child’s doctor before giving this to your child.

Use in geriatrics:

SPENTRON 1MG TABLET can be used in elderly people (65 years and older). However, consult with your doctor before taking.

INTERACTIONS

A. Drug - Drug interactions:

Before taking SPENTRON 1MG TABLET, inform your doctor if you are taking any of the following medicines:

  • other 5-HT3 receptor antagonist such as dolasetron or ondansetron (used to treat and prevent nausea and vomiting)
  • diltiazem, amlodipine (medicines used to treat an irregular heartbeat)
  • phenobarbital (used to treat epilepsy)
  • ketoconazole (used to treat fungal infections)
  • paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine, escitalopram (used to treat depression and/or anxiety)
  • buprenorphine, tramadol (used to treat acute and chronic pain)

Overdosage:

If you or anyone else accidentally take too much of SPENTRON 1MG TABLET, consult your doctor immediately. Symptoms of overdose includes mild headaches.

SYNOPSIS

Drug :   Granisetron
Pharmacological Category :    5-HT3 Receptor Antagonist
Therapeutic Indication :   Nausea and vomiting caused by chemotherapy or radiotherapy
Dosage Forms :   Tablet, Syrup, Suspension, Injection

MORE INFORMATION

  • Keep SPENTRON 1MG TABLET out of reach from children
  • Store SPENTRON 1MG TABLET at room temperature below 30°C

FAQs ABOUT SPENTRON 1MG TABLET

What is SPENTRON 1MG TABLET and why is it prescribed?

SPENTRON 1MG TABLET contains a medicine Granisetron. It is used to prevent or treat nausea (feeling sick) and vomiting (being sick) caused by other medical treatments such as chemotherapy or radiation treatment for cancer.

Does SPENTRON 1MG TABLET cause constipation?

Yes, SPENTRON 1MG TABLET may cause constipation in some individuals. Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. Ask for your doctor’s advice if constipation doesn’t improve

Can I stop taking SPENTRON 1MG TABLET when my symptoms are relieved?

Do not stop taking SPENTRON 1MG TABLET before the treatment is finished. If you stop taking SPENTRON 1MG TABLET, your symptoms may return. Ask for your doctor’s advice if you wish to stop taking this medicine.

Can I take SPENTRON 1MG TABLET during heart disease?

SPENTRON 1MG TABLET should be used with caution in patients suffering from heart disease. Consult your doctor for advice before taking SPENTRON 1MG TABLET.

What is the best time to take SPENTRON 1MG TABLET?

Always take SPENTRON 1MG TABLET as directed by your physician. SPENTRON 1MG TABLET can be taken with or without food. Your doctor will decide the correct dose and duration for you depending upon your conditions.

REFERENCES

1. KD. Tripathi. Antiemetic, Prokinetic and Digestant Drug. Essentials of medical pharmacology. Seventh edition. 2013. Page –669.

2. NIH National Library of Medicine, National center for biotechnology information. Granisetron. Pubchem. [Accessed on 26th November 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Granisetron-hydrochloride

3. Anh L. Ngo, Vwaire Orhurhu, Ivan Urits, Edwin O. Delfin, Medha Sharma, Mark R. Jones, Omar Viswanath, Richard D. Urman. Extended release granisetron: Review of pharmacologic considerations and clinical role in the perioperative setting. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. September 2019. [Accessed on 26th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625288/

4. Matti Aapro. Granisetron: an update on its clinical use in the management of nausea and vomiting. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. [Accessed on 26th November 2022] https://pubmed.ncbi.nlm.nih.gov/15561811/

5. Generics [UK] Limited. Electronic Medicines Compendium (EMC). [Revised on Jan 2021]. [Accessed on 26th November 2022] https://www.medicines.org.uk/emc/files/pil.2685.pdf

6. Atnahs Pharma UK Limited. Health Products Regulatory Authority (HPRA). [Revised in March 2021]. [Accessed on 26th November 2022] http://www.hpra.ie/img/uploaded/swedocuments/Licence_PA22657-003-003_23032021132538.pdf

7. Natco Pharma Ltd. Granisetron Tablets. Dailymed. [Revised in May 2022]. [Accessed on 26th November 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=df4b6775-4337-41e0-815a-b064d98c3fe1

8. Aspen Pharmacare. Granisetron. [Revised in January 2022]. [Accessed on 26th November 2022] https://pi-pil-repository.sahpra.org.za/wp-content/uploads/2022/03/1.3.2_Aspen-Granisetron_27-January-2022_EPIL.pdf

9. Atnahs Pharma UK Limited. Kytril (Granisetron). Pharmanovia. [Accessed on 26th November 2022] https://pharmanovia.com/product/kytril/

10. Drug Bank. Granisetron. [Accessed on 26th November 2022] https://go.drugbank.com/drugs/DB00889

USEFUL DIAGNOSTIC TESTS

  • Complete Blood Count

PRODUCT DETAILS

    Net Qty
    1 N
    Item Weight
    10 g
    Ingredient
    GRANISETRON 1 mg
    Hsn Code
    30049039
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