INTRODUCTION

SOLIAN 400MG contains amisulpride which belongs to the group of medicines called antipsychotics. It is used to treat schizophrenia. Schizophrenia is a serious mental disorder, in which you may feel, hear and see things which do not exist, have weird and frightening thoughts and make you feel alone. It may also make you feel tense, anxious or depressed.

Amisulpride acts by improving your abnormal behavior, disturbed thoughts and feelings. It can be used to treat both acute and chronic schizophrenia. Along with this treatment, your doctor might recommend you stop smoking and alcohol consumption, because it can affect the way the medicine works. Manage your stress levels by having plenty of sleep, meditation, deep breathing or by staying socially connected. 

Take SOLIAN 400MG as directed by your physician. This medicine should be taken before meals. Contact your doctor for advice if these symptom bothers you. Before taking this medicine, inform your doctor if you have breast cancer, phaeochromocytoma or pituitary tumour. This medicine is strictly not recommended for use in pregnant or breastfeeding women and in children below 18 years of age. Discuss the benefits with your doctor. The most common side effects of taking this medicine are muscle stiffness, tremor, dizziness, sleepiness and blurred vision.

USES OF SOLIAN 400MG

• Treat schizophrenia

HOW SOLIAN 400MG WORKS

It works by blocking the receptors in brain that dopamine acts on and prevent the excessive activity of dopamine and helps to control psychotic illness such as abnormal motor activity, hallucinations, aggression and anxiety.

DIRECTIONS FOR USE

Take SOLIAN 400MG as directed by your physician. Swallow the medicine as whole with plenty of water before a meal. Your doctor will decide the correct dose for you depending upon your condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF SOLIAN 400MG

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Constipation: 

Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.

Dizziness:

Try to rest and relax. Do not drive or operate any machines while you feel dizzy.

WARNING & PRECAUTIONS

INTERACTIONS

Talk to your doctor, if you are taking,

• levodopa (used to treat Parkinson's disease)
• dopamine agonists (such as ropinirole and bromocriptine)
• medicines used to reduce your heart rate (such as quinidine, disopyramide, amiodarone and sotalol)
• medicines used to treat high blood pressure and heart problems (such as diltiazem, verapamil, guanfacine or digitalis)
• other anti-psychotic medicines for mental problems
• medicines used to treat severe pain (e.g. morphine, pethidine, tramadol and indomethacin)
• medicines which induce hypokalemia such as hypokalaemic diuretics (e.g. spironolactone), IV amphotericin B, glucocorticoids or tetracosactides
• medicines to make you sleep such as barbiturates (e.g. phenobarbitone) and benzodiazepines (e.g. diazepam)
• halofantrine and mefloquine (used to treat malaria)
• anaesthetics (medicine which induces loss of sensation or consciousness)
• promethazine (used to treat nausea, allergies and sleep disturbances)
• bepridil (used to treat chest pain)
• clonidine (used to treat migraines, flushing or for high blood pressure)
• cisapride (used to treat GI problems)
• intravenous erythromycin and sparfloxacin (used to treat infections)
• intravenous vincamine (used to improve blood flow in the brain)
• pentamidine (used to treat chest infections)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT SOLIAN 400MG

Can SOLIAN 400MG affects sexual performance?

Yes. This medicine can cause difficulty in maintaining an erection, or ejaculation. Contact your doctor if this symptom troubles you.

Can SOLIAN 400MG be used in children?

No. This medicine is strictly not recommended for use in children under 18 years of age. Consult your doctor for advice before taking

Can SOLIAN 400MG cause anxiety?

This medicine helps to relieve anxiety and irritation. However, if you feel more anxious after taking this medicine, consult your doctor.

Can SOLIAN 400MG be taken at night?

Yes. Your doctor will decide the correct dose, duration and time of consumption for you depending upon your age, weight and health condition.

REFERENCES

1. KD. Tripathi. Drugs used in mental illness: Antipsychotic and Antimanic drugs. Essentials of medical pharmacology. Seventh edition. 2013.Page – 443.

2. Sanofi. Study of the Efficacy and Safety After Long-Term Treatment with Amisulpride in Schizophrenic Patients. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on April 2008] [Accessed 3rd November 2020] https://clinicaltrials.gov/ct2/show/NCT00331981

3. Katja Komossa, Christine Rummel-Kluge, Heike Hunger, Franziska Schmid, Sandra Schwarz, Joaquim I Silveira da Mota Neto, Werner Kissling, and Stefan Leucht. Amisulpride versus other atypical antipsychotics for schizophrenia. NCBI; PMC National Library of Medicine, National Institute of Health. January 2010. [Accessed 3rd November 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164462/

4. Peng Men, Zhanmiao Yi, Chaoyun Li, Shuli Qu, Tengbin Xiong, Xin Yu & Suodi Zhai. Comparative efficacy and safety between amisulpride and olanzapine in schizophrenia treatment and a cost analysis in China: a systematic review, meta-analysis, and cost-minimization analysis. BMC Psychiatry. September 2018. [Accessed 3rd November 2020] https://bmcpsychiatry.biomedcentral.com/articles/10.1186/s12888-018-1867-8

5. Milpharm Limited, APL Swift Services (Malta) Ltd. Electronic Medicines Compendium (EMC); [Revised on April 2020] [Accessed 3rd November 2020] https://www.medicines.org.uk/emc/files/pil.548.pdf

6. Delpharm Dijon. Electronic Medicines Compendium (EMC); [Revised on October 2019] [Accessed 3rd November 2020] https://www.medicines.org.uk/emc/files/pil.3964.pdf