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Drug Information

What is Montelukast + Rupatadine combination used for?

Montelukast + Rupatadine combination is used for the treatment of the following conditions:

  • Asthma
  • Exercise-induced bronchospasm
  • Allergic rhinitis
  • Hay fever
  • Urticaria

Montelukast + Rupatadine combination may also be prescribed for other conditions as determined by the doctor.

How does Montelukast + Rupatadine combination work?

In Montelukast + Rupatadine combination, Montelukast belongs to the class of drugs called as the leukotriene receptor antagonist. This drug acts by blocking the action of certain receptors in lungs. This helps in widening of the airways and relieving the symptoms.

Rupatadine belongs to the class of drugs called as the anti-histamines. This drug acts by binding to histamine receptors and prevents the release of allergic chemicals. This helps in relieving the allergic symptoms.

How to take Montelukast + Rupatadine combination?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Montelukast + Rupatadine combination as prescribed by your doctor.

Swallow the tablet whole. Do not crush or chew the tablet. Take the drug with or without food. However, taking the drug with food prevents stomach upset.

If you miss a dose of Montelukast + Rupatadine combination, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What are the drugs that interact with Montelukast + Rupatadine combination?

Drugs that interact with Montelukast + Rupatadine combination include the following:

  • Acetaminophen
  • Amiodarone
  • Aspirin
  • Atropine
  • Ergotamine
  • Ketoconazole
  • Rifampicin
  • Somatropin
  • Tamoxifen
  • Zafirlukast

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Montelukast + Rupatadine combination?

The following are the most common side effects of Montelukast + Rupatadine combination:

  • Increased appetite
  • Irritability
  • Nausea
  • Abdominal pain
  • Fever
  • Muscle pain
  • Increased weight

The following are the severe side effects and you may require immediate medical attention:

  • Bloody nose
  • Tightness of chest
  • Profuse sweating
  • Joint pain
  • Shortness of breath

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Montelukast + Rupatadine combination?

  • Avoid using the medicine if you are allergic to Montelukast + Rupatadine combination or similar drugs.
  • Consult the doctor before taking any other drug along with Montelukast + Rupatadine combination.
  • Do not stop using the medication abruptly unless instructed by the doctor.
  • Do not exceed the dose more than what is prescribed.

You are advised not to take Montelukast  + Rupatadine combination if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Montelukast + Rupatadine combination?

  • Tell your doctor if you have any history of respiratory diseases, kidney and liver diseases.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Inform the doctor if you are pregnant or breastfeeding.

Frequently asked questions about Montelukast + Rupatadine

  1. Can I use aspirin while taking Montelukast + Rupatadine combination?
  2. You should avoid taking Aspirin with Montelukast + Rupatadine combination, as it may increase the risk of complications.

  3. Is it safe to use Montelukast + Rupatadine combination if I have a history of kidney disease?
  4. Montelukast + Rupatadine combination is not recommended in patients with kidney disease. However, consult the doctor before using the drug.

  5. Do I need to avoid any foods while using Montelukast + Rupatadine combination?
  6. Avoid consuming grapefruit and grapefruit juice while using Montelukast + Rupatadine combination, as it increases the drug toxicity in the body.

  7. Is it safe to take Montelukast + Rupatadine combination in patients with lactose intolerance?
  8. Montelukast + Rupatadine combination should be avoided by the patients with lactose intolerance. However, inform the doctor before using Montelukast + Rupatadine combination.

  9. How should Montelukast + Rupatadine combination be stored?
  10. Montelukast + Rupatadine combination must be stored at room temperature, away from sunlight.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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