Senacept 30mg Tablet 10'S

Hyperthyroidism Rx required

Best Price*  ₹ 650.00
(Inclusive of all taxes) *10 Tablet(s) in a Strip * Mfr: Lupin Ltd * Country of Origin: NA



INTRODUCTION

SENACEPT 30MG contains cinacalcet which belongs to a group of medicines called calcimimetic agent that increases the sensitivity of the calcium-sensing receptor to activation by extracellular calcium. It treats problem with the organs called parathyroid glands. The parathyroids are four small glands in the neck, near thyroid gland, that produce the parathyroid hormone (PTH). Hyperparathyroidism (HPT) is a condition where the parathyroid gland may become overactive and make too much PTH. In this condition the calcium stored in the bones move into the blood leading to hypercalcemia (too much calcium in the blood).

Secondary hyperparathyroidism (SHPT) describes an alteration in bone and mineral metabolism that occurs as a direct result of chronic kidney disease (CKD). The parathyroid gland is the central organ responsible for regulating these adaptive responses leading to secondary hyperparathyroidism. Parathyroid hormone helps prevent low calcium levels by acting on the bones, intestine, and kidneys. SENACEPT 30MG works by controlling levels of the parathyroid hormone (PTH), calcium and phosphorous in body.

Children under the age 18 with parathyroid cancer or primary hyperparathyroidism must not take this medicine. Do not drive or operate machines, if you experience side effects such as dizziness and seizures. If you are pregnant or breast-feeding, think you may be pregnant or planning to have a baby, ask your doctor for advice before taking this medicine. The usual starting dose for this medicine in adults is 30 mg twice per day or as directed by your physician. Swallow the medicine whole with plenty of water. The most common side effects are nausea, vomiting, dizziness, rash, muscle pain, loss of appetite, headache, etc.

USES OF SENACEPT 30MG

  • Secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) on dialysis
  • Hypercalcemia in patients with Parathyroid carcinoma and primary hyperparathyroidism (HPT)

HOW SENACEPT 30MG WORKS

SENACEPT 30MG works by controlling levels of the parathyroid hormone (PTH), calcium and phosphorous in body.

DIRECTIONS FOR USE

The usual starting dose for this medicine in adults is 30 mg twice per day or as prescribed by your doctor. Swallow the medicine whole with plenty of water.

SIDE EFFECTS OF SENACEPT 30MG

SERIOUS

  • numbness or tingling around mouth, muscle aches or cramps and seizures. These may be signs of low calcium levels (hypocalcaemia)
  • swelling of face, lips, mouth, tongue or throat which may cause by difficulty in swallowing or breathing (angioedema)

COMMON

  • dizziness, headache
  • nausea or vomiting
  • constipation
  • feeling weak
  • loss (anorexia) or decrease of appetite
  • muscle pain (myalgia)
  • weakness (asthenia)
  • rash
  • reduced testosterone levels
  • high potassium levels in the blood (hyperkalaemia)
  • allergic reactions (hypersensitivity)
  • diarrhea
  • indigestion

HOW TO MANAGE SIDE EFFECTS

Constipation:

Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.

Nausea and vomiting:

Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

WARNING & PRECAUTIONS

PREGNANCY

SENACEPT 30MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.

BREASTFEEDING

SENACEPT 30MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.

DRIVING AND USING MACHINES

Do not drive or operate any machinery while taking this medicine, it may make you feel dizziness, seizures.

ALCOHOL

Consumption of alcohol is not recommended during treatment with this medicine.

KIDNEY

SENACEPT 30MG should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.

LIVER

SENACEPT 30MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.

ALLERGY

Do not take if you are allergic to the medicine.

HEART DISEASE

If you have any heart related problems, consult your doctor for advice before taking this medicine.

OTHERS

Do not take SENACEPT 30MG if you have low levels of calcium in your blood.

INTERACTIONS

Talk to your doctor if you are taking medicines used to:

  • treat the skin and fungal infections
  • treat the bacterial infections (telithromycin, rifampicin and ciprofloxacin)
  • treat HIV infection and AIDS (ritonavir)
  • treat depression (fluvoxamine)
  • treat depression
  • relieve cough (dextromethorphan)
  • treat the changes in heart rate (flecainide and propafenone)
  • treat high blood pressure

SYNOPSIS

Drug :   Cinacalcet
Pharmacological Category :   Calcimimetics
Therapeutic Indication :   Hyperparathyroidism
Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT SENACEPT 30MG

Can SENACEPT 30MG be used in pregnant women?

No. It is not recommended for use in the pregnant women. Consult your doctor before taking.

Does SENACEPT 30MG cause hypocalcemia?

It can cause acute, severe and symptomatic hypocalcaemia in susceptible patients, possibly those with prolonged high bone turnover states or those not receiving VDRA therapy.

REFERENCES

1. Bharath M. Reddy, MD, Howard S. Weintraub, MD, and Arthur Z. Schwartzbard, MD, A New Approach to Treating an Old Problem, [Approved on 2010] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014127/pdf/20101200s00004p641.pdf

2. K.D.Tripathi, Essentials of medical pharmacology, Cardiovascular drugs, Chapter 39 - Anti anginal and other ischaemic drugs, Page – 554.

3. Lionel H. Opie, Bernard J. Gersh, Drugs for the heart, Drugs Used in anti anginals, Eighth Edition, 2013. Page – 55-56.

4. Amgen Europe B.V; Electronic Medicines Compendium (EMC); [Revised on 08/2017] [Accessed 04 Nov 2020] https://www.medicines.org.uk/emc/files/pil.5599.pdf

5. Amgen Inc.; U.S. Food & Drug Administration; [Revised on 08/2011] [Accessed 04 Nov 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021688s017lbl.pdf

Manufacturer/Marketer Details

    Country Of Origin
    NA
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