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Drug Information

What is Dapoxetine + Sildenafil combination used for?

Dapoxetine + Sildenafil combination tablet is used for the treatment of premature ejaculation and erectile dysfunction.

Dapoxetine + Sildenafil combination may also be prescribed for other conditions as determined by the doctor.

How does Dapoxetine + Sildenafil combination work?

In Dapoxetine + Sildenafil combination, Dapoxetine belongs to the class of drugs called selective serotonin reuptake inhibitors. It acts by increasing the levels of a certain chemical in the body, thereby causing a delay in ejaculation. Thus, it helps in treating premature ejaculation.

Sildenafil belongs to the class of drugs called phosphodiesterase (PDE-5) inhibitors. The drug acts by increasing the blood flow to the penis by relaxing the smooth muscles. Thus, it helps in treating erectile dysfunction.

How to take Dapoxetine + Sildenafil combination?

The dosage and the drug form depend on the age, weight and medical condition of an individual. Take Dapoxetine + Sildenafil combination tablet as prescribed by your doctor.

  • Swallow the tablet Do not crush or chew the tablet.
  • Take the drug with or without food. However, taking the drug with food prevents stomach upset.

If you miss a dose of Dapoxetine + Sildenafil combination, please take it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What are the drugs that interact with Dapoxetine + Sildenafil combination?

Drugs that interact with Dapoxetine + Sildenafil combination are:

  • Amlodipine
  • Captopril
  • Diltiazem
  • Erythromycin
  • Fluconazole
  • Furosemide
  • Ketoconazole
  • Tramadol
  • Verapamil
  • Warfarin

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of Dapoxetine + Sildenafil combination?

The following are the most common side effects of Dapoxetine + Sildenafil combination:

  • Dizziness
  • Stomach pain
  • Diarrhoea
  • Headache
  • Light-headedness
  • Flushing
  • Vision disorders
  • Ringing in ears
  • Dry mouth
  • Sleeplessness

The following are the severe side effects, and you may require immediate medical attention:

  • Increased heart rate
  • Burning in extremities
  • Painful urination
  • Sensitivity to light
  • Prolonged erection

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while taking Dapoxetine + Sildenafil combination?

  • Do not drive or operate heavy machinery if Dapoxetine + Sildenafil combination causes dizziness and vision problems.
  • Consult the doctor before taking any other drug along with Dapoxetine + Sildenafil combination.
  • Avoid consumption of alcohol as it may alter the absorption of Dapoxetine + Sildenafil
  • Keep the medication out of reach of children.
  • Avoid grapefruit juice while taking Dapoxetine + Sildenafil combination as it may increase the plasma levels of Dapoxetine + Sildenafil.

You are advised not to take Dapoxetine + Sildenafil combination if

  • it has passed the expiry date of the medicine printed on the pack.
  • the foil or packaging is torn or shows signs of tampering or there is discolouration.

What should you tell your doctor before taking Dapoxetine + Sildenafil combination?

  • Inform your doctor if you have any pre-existing medical conditions, such as heart problems, kidney disease, liver disease, high or low blood pressure, dehydration), penile disorders, history of prolonged erection, sickle cell anaemia, leukaemia, multiple myeloma and eye problems.
  • Inform the doctor if you have any history of allergic reaction with the usage of Dapoxetine + Sildenafil
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplement

Frequently asked questions about Dapoxetine + Sildenafil combination

  1. How should Dapoxetine + Sildenafil combination be stored?
  2. Dapoxetine + Sildenafil combination should be stored at a temperature between 15 – 20°C.

  3. Is it safe to alter the dose of Dapoxetine + Sildenafil combination?
  4. It is not advisable to alter the dose prescribed. Consult your doctor for dose-related queries.

  5. Can I recommend Dapoxetine + Sildenafil combination to others?
  6. It is not advisable to recommend drugs to others as the severity of the condition and medical history is not same for every individual.


The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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