Sandimmun 50mg Injection 1ml

Auto Immune Disease Rx required

Best Price*  ₹ 212.62
MRP ₹265.78
(Inclusive of all taxes) * Mkt: Novartis India Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout


SANDIMMUN 50MG contains Cyclosporin which belongs to the group of medicines called immunosuppressive agents. Immunosuppressive agents are the drugs that suppress or reduces the strength of body’s immune system. It is used to prevent graft rejection in patients who have had an organ transplant, bone marrow and stem cell transplantation.

It can also be used to treat various autoimmune disease like severe rheumatoid arthritis, nephrotic syndrome (kidney disease) and skin diseases (atopic dermatitis and psoriasis). Cyclosporin blocks the development of cells which attack the affected transplanted tissue and suppress abnormal immune function thus preventing the rejection of transplanted organs.

Limit your exposure to sunlight and UV light by wearing protective clothing and by applying a sunscreen to prevent skin cancer. Avoid consumption of alcohol or grapefruit juice while taking this medicine. This medicine should not be given to children for any non-transplant disease, except for nephrotic syndrome. Do not take this medicine if you have any uncontrollable infection or any type of cancer. Consult your doctor for advice.


  • Prevents graft rejection in patients who have undergone an organ transplant, bone marrow and stem cell transplantation
  • Treats severe rheumatoid arthritis
  • Treats nephrotic syndrome (kidney disease)
  • Treats skin diseases (such as atopic dermatitis, or eczema and psoriasis)


Cyclosporin is a calcineurin inhibitor that inhibits the activation of T-lymphocytes (cells catalyzing immune reaction). It works by inhibiting the production of various cytokines (e.g. IL-1, IL-2) involved in the regulation of T-cell activation. These effects of cyclosporine on T cells and on connective tissue cells can produce a range of cytokines. These in turn promote proliferation and differentiation of antigen activated B cells into antibody (Ab) secreting plasma cells. Antibodies finally bind and inactivate the antigen.


SANDIMMUN 50MG will be given to you by a doctor or a nurse into the vein (intravenously) as an infusion drip. Your doctor will decide the correct dose for you depending upon your condition.



  • severe allergic reaction (such as flushing of face and upper chest, fluid in lungs, shortness of breath, blood pressure changes and accelerated heartbeat)
  • fever or sore throat
  • signs of brain infection (e.g. changes in sight, loss of coordination, memory loss, difficulty in speaking, muscle weakness)
  • confusion
  • feeling disorientated
  • feeling agitated, sleeplessness
  • coma, paralysis
  • stiff neck
  • swelling at the back of eye
  • yellowing of skin and eyes
  • loss of appetite
  • dark colored urine
  • problems in urination
  • pale skin, feeling tired
  • bruising or bleeding


  • high blood pressure
  • headache
  • tremor of your body
  • unwanted growth of body and facial hair
  • fits (seizures)
  • tiredness, loss of appetite
  • nausea, vomiting, abdominal pain, constipation, diarrhea
  • acne, hot flushes
  • fever
  • feeling numb or tingling
  • muscle pain
  • overgrowth of gum tissue


  • numbness or tingling in fingers and toes
  • severe upper stomach pain
  • swelling of face, stomach, hands and/or feet
  • chest pain
  • changes in menstrual cycle
  • breast enlargement in men


Nausea or vomiting:

Try taking this medicine with, or just after meal. Stick to simple meals. Do not eat rich or spicy food.


Eat fibre rich foods like fresh fruit, vegetables and cereals. Drink plenty of water. Exercise more regularly.


Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Stomach pain:

Try to rest and relax. You can eat and drink slowly or have smaller and frequent meals. Keeping a heat pad on your stomach may also help. If still pain persists, speak to your doctor.



SANDIMMUN 50MG should be used with caution in pregnant women. Consult your doctor before taking this medicine.


SANDIMMUN 50MG should be used with caution in breast feeding women. Consult your doctor before taking this medicine.


Do not drive or operate any machines if your ability is affected by this medicine.


Avoid consumption of alcohol while taking this medicine, as it may increase the risk of side effects.


Do not take SANDIMMUN 50MG if you are suffering from severe kidney disease. Consult your doctor for advice.


SANDIMMUN 50MG should be taken with caution in patients with severe liver disease. Consult your doctor for advice.


Do not take this medicine if you are allergic to cyclosporin.


Do not take SANDIMMUN 50MG if you are suffering from uncontrollable high blood pressure. Consult your doctor for advice.


Do not take this medicine, if you have:

  • any uncontrollable infection or any type of cancer
  • gout, alcohol-related problems or epilepsy, low blood magnesium levels, high blood potassium levels, or if you need to have a vaccination


Talk to your doctor, if you are taking,

  • medicines that affects your potassium levels (e.g. spironolactone, aldosterone)
  • medicines used for heart problems or high blood pressure (e.g. diltiazem, nicardipine, verapamil, amiodarone, nifedipine or digoxin)
  • medicines used to treat epilepsy (e.g. carbamazepine or phenytoin)
  • medicines used to treat HIV (e.g. saquinavir, indinavir, ritonavir)
  • antibiotics (used to treat infections) e.g. erythromycin, gentamycin, tobramycin, ciprofloxacin
  • anti-fungal agents (used to treat fungal infection) e.g. voriconazole, terbinafine, amphotericin B)
  • cholic acid and derivatives (used to treat gallstones)
  • telaprevir (used to treat hepatitis C).
  • barbiturates (used to induce sleep)
  • octreotide (used to treat acromegaly)
  • orlistat (used to help weight loss)
  • St. John’s wort (used to treat depression)
  • ticlopidine (used after a stroke)
  • repaglinide (oral anti-diabetic medicine)
  • ambrisentan (used to treat pulmonary arterial hypertension)


Drug :   Cyclosporin
Pharmacological Category :   Immunosuppressive agent, Calcineurin inhibitor
Therapeutic Indication :   Prevents graft rejection, Treats auto immune disease
Dosage Forms :  

Capsule, Oral suspension, Eye drops, Injection


Store below 20-25°C and keep out of reach of children.


Can SANDIMMUN 50MG cause cancer?

Yes. This medicine increases your risk of developing cancers, particularly of the skin and lymphoid system. Limit your exposure to sunlight and UV light by wearing appropriate protective clothing and applying a sunscreen with a high protection factor often while taking this medicine.

Can SANDIMMUN 50MG cause hair loss?

This medicine does not cause any hair loss. However, if you experience any unusual symptoms, contact your physician.


1. KD Tripathi. Immunosuppressant drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 878-881.

2. Alan M. Krensky, William M. Bennett and Flavio Vincenti. Immunosuppressants, Tolerogens and Immunostimulants. Goodman & Gilman’s: The pharmacological basics of therapeutics. 12th Edition. New York, New York: McGraw-Hill Medical, 2011. Page – 1009-1012.

3. NeuroVive Pharmaceutical AB. A Study to Compare the Bioavailability and Pharmacokinetics of Cyclosporine After Intravenous Administration of NEUROSTAT®, a CREMOPHOR® EL-free Lipid Emulsion, and SANDIMMUNE® Injection (a Suspension of Cyclosporine in CREMOPHOR® EL) in Healthy Volunteers. NIH U.S. National Library of Medicine [Revised on August 2014] [Accessed 29th October 2020]

4. Matthew B. Jensen, Rajeev Krishnaney-Davison, Laura K. Cohen and Su-Chun Zhang. Injected Versus Oral Cyclosporine for Human Neural Progenitor Grafting in Rats. NCBI; PMC US National Library of Medicine, National Institute of Health. April 2012 [Accessed 29th October 2020]

5. Novartis Pharmaceuticals UK Limited; Electronic Medicines Compendium (EMC); [Revised on March 2020] [Accessed 29th October 2020]


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