INTRODUCTION

SALBAIR I TRANSHALER is a combination of Ipratropium and Levosalbutamol which belongs to the group of medicines called Bronchodilator agents and Adrenergic beta-agonists, respectively. SALBAIR I TRANSHALER is used in adults, adolescents, and children (aged 4 years and above) to treat/prevent bronchospasm (tightening of airway muscles) with reversible obstructive airway diseases such as asthma, COPD (inflammatory lung disease), bronchitis (inflammation of airways), and/or emphysema (lung disease that cause shortness of breath).

SALBAIR I TRANSHALER is not recommended for use in patients allergic to ipratropium, levosalbutamol, and/or atropine.

Before using SALBAIR I TRANSHALER, inform your doctor if you have high blood pressure, seizures, diabetes, narrow angle glaucoma (increased eye pressure), lung problems (such as asthma), heart problems (such as coronary insufficiency, cardiac arrhythmias), kidney problems (such as renal impairment), and/or liver problems (such as hepatic impairment).

SALBAIR I TRANSHALER is generally not recommended for use in pregnant women unless it is clearly necessary. It is advised to be used with caution in breastfeeding women only if necessary since it is not known whether the medicine passes through breast milk.

SALBAIR I TRANSHALER should be used with caution in children and adolescents (aged 4 to 18 years) and is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.

The most common side effects using SALBAIR I TRANSHALER are dry mouth, sore throat, stuffy nose, throat irritation, dizziness, headache, nausea, and/or vomiting. Consult your doctor if any of these symptoms worsens.

USES OF SALBAIR I TRANSHALER

• Treats/prevents bronchospasm with reversible obstructive airway diseases such as asthma, COPD, bronchitis, and/or emphysema in affected individuals

HOW SALBAIR I TRANSHALER WORKS

SALBAIR I TRANSHALER provides ease in breathing from bronchospasm (constricted airway muscles), where Ipatropium and Levosalbutamol work together to relax airway muscles which results in widening of airways providing relief from obstructive airflow and easy in breathing from bronchospasm associated with reversible obstructive airway diseases (such as asthma, COPD) in affected individuals.

DIRECTIONS FOR USE

Take SALBAIR I TRANSHALER as advised by your physician. It is for inhalation use only. Remove the cap and shake the inhaler. Insert the inhaler into spacer and breath out. Press down the inhaler and breath in slowly through the inhaler. Hold your breath for a count of 10 and slowly breath out. Close the inhaler after use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF SALBAIR I TRANSHALER

HOW TO MANAGE SIDE EFFECTS

Dry mouth:

Try to drink plenty of cold water and sip on cold unsweetened drinks and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptom gets worse.

Dizziness:

Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.

Headache:

If SALBAIR I TRANSHALER causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking SALBAIR I TRANSHALER. If it lasts more than a week or severe, inform your doctor.

Nausea and vomiting:

Take SALBAIR I TRANSHALER with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.

Constipation:

Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.

Diarrhoea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult and inform your doctor if the symptom worsens.

Indigestion:

Try to have smaller and more frequent meals and drink slowly. Reduce consumption of coffee, cola, tea, or alcohol and lose weight if you are obese.  Try to avoid smoking and don’t have rich, fatty or spicy foods. Consult your doctor and inform if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

SALBAIR I TRANSHALER is generally not recommended for use in pregnant women unless it is clearly necessary.  Consult your doctor before using SALBAIR I TRANSHALER.

BREASTFEEDING

SALBAIR I TRANSHALER should be used with caution in breastfeeding women only if clearly necessary since it is unknown whether the medicine passes through breast milk. Consult your doctor before using the medicine.

DRIVING AND USING MACHINES

Do not drive/operate machines if you feel dizzy, and/or experience accommodation disorder, dilated pupils/blurred vision while using SALBAIR I TRANSHALER.

KIDNEY

SALBAIR I TRANSHALER should be used with caution in patients with kidney problems such as renal impairment. Consult your doctor before using SALBAIR I TRANSHALER.

LIVER

SALBAIR I TRANSHALER should be used with caution in patients with liver problems such as hepatic impairment. Consult your doctor before using SALBAIR I TRANSHALER.

ALLERGY

Do not take SALBAIR I TRANSHALER if you are allergic to ipratropium, levosalbutamol, atropine, and/or any other ingredients of the medicine.

LUNGS

SALBAIR I TRANSHALER should be used with caution in patients with lung problems such as asthma. Consult your doctor before using the medicine. 

HEART DISEASE

SALBAIR I TRANSHALER should be used with caution in patients with heart problems such as coronary insufficiency, cardiac arrhythmias. Consult your doctor before using SALBAIR I TRANSHALER.

INTERACTIONS

A. Drug-Drug interactions:

Before using SALBAIR I TRANSHALER, inform your doctor if you are taking any of the following medicine:

• medicines used to treat high blood pressure such as beta-adregenic/receptor blocking agents (Ex. propanolol, metoprolol, atenolol)
• anticholinergic agents (medicines used to block acetylcholine) Ex. atropine, benztropine
• diuretics (used to treat high blood pressure) Ex. chlorothiazide, chlorthalidone
• monoamine oxidase inhibitors/tricyclic antidepressants (medicines used to treat depression) Ex. selegiline, phenelzine, amitriptyline, imipramine

B. Drug–Food interactions:

SALBAIR I TRANSHALER is not recommended for use in patients allergic to soyabean, and/or other related food products such as peanut.

Overdosage:

If you or anyone else accidentally take too much of SALBAIR I TRANSHALER, then consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are seizures, chest pain, high/low blood pressure, fast heartbeat, irregular heartbeats, nervousness, headache, tremor, dry mouth, palpitation, nausea, dizziness, fatigue, weakness, sleeplessness, hypokalaemia (low potassium level in blood), and/or visual accommodation disorder.

SYNOPSIS

MORE INFORMATION

• Keep SALBAIR I TRANSHALER out of reach of children
• Do not store SALBAIR I TRANSHALER above 30°C

FAQs ABOUT SALBAIR I TRANSHALER

What is SALBAIR I TRANSHALER used for?

SALBAIR I TRANSHALER is used in adults, adolescents, and children (aged 4 years and above) to treat/prevent bronchospasm (tightening of airway muscles) with reversible obstructive airway diseases such as asthma, COPD (inflammatory lung disease), bronchitis (inflammation of airways), and/or emphysema (lung disease that cause shortness of breath).

What are the side effects of SALBAIR I TRANSHALER?

The most common side effects using SALBAIR I TRANSHALER are dry mouth, sore throat, stuffy nose, throat irritation, dizziness, headache, nausea, and/or vomiting. Consult your doctor if any of these symptoms worsens.

How SALBAIR I TRANSHALER works?

SALBAIR I TRANSHALER provides ease in breathing from bronchospasm (constricted airway muscles), where Ipatropium and Levosalbutamol work together to relax airway muscles which results in widening of airways providing relief from obstructive airflow and easy in breathing from bronchospasm associated with reversible obstructive airway diseases (such as asthma, COPD) in affected individuals.

How SALBAIR I TRANSHALER should be administered?

Take SALBAIR I TRANSHALER as advised by your physician. It is for inhalation use only. Remove the cap and shake the inhaler. Insert the inhaler into spacer and breath out. Press down the inhaler and breath in slowly through the inhaler. Hold your breath for a count of 10 and slowly breath out. Close the inhaler after use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Can SALBAIR I TRANSHALER be used in pregnant and breastfeeding women?

No, SALBAIR I TRANSHALER is generally not recommended for use in pregnant women unless it is clearly necessary. It should be used with caution in breastfeeding women only if necessary since it is not known whether the medicine pass through breast milk. Consult your doctor before using SALBAIR I TRANSHALER.

REFERENCES

1. K.D. Tripathi. Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia. Essentials of medical pharmacology. Seventh edition. 2013. Page- 116.

2. Hongzhen Xu, Lin Tong, Peng Gao,  Yan Hu, Huijuan Wang, Zhimin Chen, Luo Fang. Combination of ipratropium bromide and salbutamol in children and adolescents with asthma: A meta-analysis. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. [Revised in February 2021] [Accessed on 27th May 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901745/

3. CiplaMed. DUOLIN Inhaler. [Revised in April 2019] [Accessed on 27th May 2022] https://www.ciplamed.com/content/duolin-inhaler

4. CiplaMed. DUOLIN forte Inhaler.[Accessed on 27th May 2022] https://www.ciplamed.com/product-index-listing?field_speciality_tid=All&field_other_specialty_tid=All&field_brand_value=&field_molecule_value=levo

USEFUL DIAGNOSTIC TESTS

• Spirometry
• Chest X-ray
• CT scan

AUTHOR DETAILS

Written By Dr. K .AZEEM HUSSAIN, B.D.S
Last updated on 26 Nov 2022 | 07:08 PM(IST)