INTRODUCTION

S R T 25MG contains Sertraline which belongs to a group of medicines called Selective Serotonin Re-uptake Inhibitors. It is used to treat depression and or anxiety disorders. It works by increasing the levels of a mood-enhancing chemical called serotonin in the brain that stabilizes our mood, feelings of well-being, and happiness. 

Take S R T 25MG according to the dose and frequency as advised by your doctor. Swallow the medicine whole, do not crush or chew. It can be taken with or without food. This medicine is not recommended in children and adolescents less than 18 years old, except for patients with Obsessive Compulsive Disorder (OCD). The common side effects are nausea, insomnia, headache and diarrhea. Consumption of alcohol is not recommended during treatment with this medicine. Before taking this medicine, inform your doctor if you have epilepsy, diabetes, liver, kidney and heart problems and if you are pregnant or breastfeeding women. It should not be taken in combination with grapefruit juice, as this may increase the level of medicine in your body.

USES OF S R T 25MG

• Treat depression and anxiety disorders

HOW S R T 25MG WORKS

S R T 25MG works by increasing the levels of a mood-enhancing chemical called serotonin in the brain.

DIRECTIONS FOR USE

Take S R T 25MG according to the dose and frequency as advised by your doctor. Swallow the medicine whole, do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF S R T 25MG

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to simple normal meals and do not eat rich or spicy foods.

Headache:

Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.

Diarrhoea:

Drink lot of fluid, such as water or squash, to avoid dehydration. Do not take any other medicine without consulting your doctor.

WARNING & PRECAUTIONS

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

• moclobemide, lithium, amitriptyline, nortriptyline, nefazodone, fluoxetine, fluvoxamine (used to treat depression), selegiline (used to treat Parkinson’s disease)
• linezolid and methylene blue (used to treat high levels of methaemoglobin in the blood)
• pimozide, perphenazine, levomepromazine and olanzapine (used to treat mental disorders)
• St. John’s Wort (herbal medicine)
• tramadol, ibuprofen, acetylsalicylic acid (used to treat severe pain)
• fentanyl mivacurium and suxamethonium (used in anaesthesia)
• sumatriptan (to treat migraines)
• warfarin (used to treat blood clot)
• diazepam
• diueretics, verapamil, diltiazem, flecainide, propafenone
• phenytoin, phenobarbital, carbamazepine (used to treat epilepsy)
• tolbutamide (used to treat diabetes)
• cimetidine, omeprazole, lansoprazole, pantoprazole (used to treat ulcers)
• rifampicin, clarithromycin, telithromycin, erythromycin (used to treat bacterial infections)
• fluconazole, ketoconazole, itraconazole, posaconazole, voriconazole (used to treat fungal infections)
• ritonavir, telaprevir (used to treat HIV/AIDS)
• aprepitant (used to prevent nausea and vomiting after an operation or chemotherapy)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT S R T 25MG

What does S R T 25MG do to the body?

It works by affecting the balance of chemicals in the brain. It increases the level of a neurotransmitter called serotonin in the brain.

Is S R T 25MG effective?

Yes it is effective if used in the correct dose and duration directed by your doctor.

Can I have S R T 25MG with grapefruit?

It should not be taken in combination with grapefruit juice, as this may increase the level of medicine in your body.

REFERENCES

1. KD Tripathi MD. Drugs Used in Mental Illness: Antidepressant and Anti-anxiety: antidepressant and anti- anxiety drugs. Drugs Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page - 463.

2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page -1253-1258.

3. James. M O Donnell and Richard C Shelton. Neuropharmacology: Drugs therapy of Depression and Anxiety disorders. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page - 405.

4. Ethan A. Poweleit, BS, Stacey L. Aldrich, MS, Lisa J. Martin, PhD, David Hahn, Jeffrey R. Strawn, MD, and Laura B. Ramsey. Pharmacogenetics of Sertraline Tolerability and Response in Pediatric Anxiety and Depressive Disorders: Journal of child and adolescent psychopharmacology; vol - 29, No- 5, 2019; https://www.liebertpub.com/doi/pdfplus/10.1089/cap.2019.0017

5. Milpharm Limited, Electronic Medicines Compendium (EMC); [Revised Aug 2020] [Accessed Nov 11, 2020] https://www.medicines.org.uk/emc/files/pil.5760.pdf  

6. Pfizer Roerig, 1991; U.S. Food & Drug Administration; [Revised Dec 2016] [Accessed Nov 11, 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/019839S74S86S87_20990S35S44S45lbl.pdf