INTRODUCTION

S AMWELL 5MG contains Amlodipine which belongs to a group of medicines called calcium antagonists. It is used to treat high blood pressure (hypertension), chest pain due to narrowing of the blood vessels of the heart muscle (angina pectoris) or a rare form of chest pain due to cramping of the blood vessels of the heart muscle (prinzmetal or variant angina). It can be used alone or in combination with other medicines to treat these conditions.

High blood pressure usually occurs from blood pushing too hard against your blood vessels. Pain or discomfort that keeps coming back when part of your heart does not get enough blood is defined as angina.

Always take this medicine exactly as your doctor has directed you. It should be taken with a glass of water with or without food. Drinking grapefruit juice and taking grapefruit should be avoided while taking this medicine. Before taking it, tell your doctor know if you have any liver, heart, or kidney problems. Inform your doctor what other medicines you are taking, especially those used to treat high blood pressure or heart conditions. This medicine is not recommended for use in children aged under 6 years.

USES OF S AMWELL 5MG

• High blood pressure (hypertension)
• Angina

HOW S AMWELL 5MG WORKS

• High blood pressure: This medicine reduces blood pressure by relaxing blood vessels, so that blood passes through them more easily
• Angina: This medicine improves blood supply to the heart muscle which then receives more oxygen and as a result chest pain is prevented

DIRECTIONS FOR USE

Always take this medicine exactly as your doctor has directed you. It should be taken with a glass of water with or without food. Drinking grapefruit juice and taking grapefruit should be avoided while taking this medicine.

SIDE EFFECTS OF S AMWELL 5MG

HOW TO MANAGE SIDE EFFECTS

Feeling sick (nausea) or indigestion:

Have simple meals and avoid eating rich or spicy foods.

Drowsiness or dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Constipation:

Add fruits, vegetables whole grains and other high-fiber foods to your diet.

WARNING & PRECAUTIONS

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:

• any other hypertensives
• verapamil, diltiazem
• ketoconazole and itraconazole (used to treat fungal infections)
• ritonavir
• clarithromycin, erythromycin and telithromycin, rifampicin, rifabutin (antibiotics)
• nefazodone (used to treat depression)
• dexamethasone (used to treat inflammatory and autoimmune conditions)
• dantrolene
• simvastatin (cholesterol lowering medicine)
• cyclosporine, tacrolimus (immunosuppressant)
• phenobarbital, phenytoin and carbamazepine (used for epilepsy)
• sildenafil (used for impotence)

SYNOPSIS

MORE INFORMATION

Store in a cool and dry place and keep out of reach of children.

FAQs ABOUT S AMWELL 5MG

How long does it take for S AMWELL 5MG to work?

It starts working on the same day it’s taken and however, it may take weeks to see the full effect.

For how long do I need to take S AMWELL 5MG?

Continue taking the medicine even if you feel better or if you do not notice any considerable difference and do not stop taking without consulting your doctor.

What should I avoid while taking S AMWELL 5MG?

Consult your doctor first before starting any new prescription or non-prescription medicines or supplements. Follow low sodium and low-fat diet and adhere to the lifestyle changes as advised by your doctor. Drinking grapefruit juice and taking grapefruit should be avoided while taking this medicine.

REFERENCES

1. KD Tripathi MD. Anti-anginal and other anti-ischaemic drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 549.

2. Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page 758-60.

3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. Page 60-61.

4. Opie LH. Calcium Channel Blockers. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. Page 86-88.

5. Hassan Fares, James J DiNicolantonio, James H O'Keefe and Carl J Lavie. Amlodipine in hypertension: a first-line agent with efficacy for improving blood pressure and patient outcomes, Sep 28, 2016; [Accessed Oct 6, 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051471/ 

6. Accord Healthcare Limited. Electronic Medicines Compendium (EMC); [Revised July 2018] [Accessed Oct 6, 2020] https://www.medicines.org.uk/emc/files/pil.6068.pdf

7. Pfizer Labs. 1987, U.S. Food & Drug Administration [Revised May 2011] [Accessed Oct 6, 2020] https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019787s047lbl.pdf

USEFUL DIAGNOSTIC TESTS

• Kidney Function Test