ROWASA Pellet 500mg

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By Abbott India Ltd
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Drug Information for ROWASA Pellet 500mg

What is ROWASA PELLET used for?

ROWASA PELLET is used for the treatment of ulcerative colitis. It is also recommended to treat mild to moderate Crohn’s disease.

ROWASA PELLET may also be prescribed for other conditions as determined by the doctor.

How does ROWASA PELLET work?

ROWASA PELLET belongs to the class of drugs called anti-inflammatory agents. This drug acts by increasing the mucosal production and diminishing the inflammation by inhibiting the synthesis of prostaglandins and blocking the action of cyclooxygenase enzymes. Inhibition of prostaglandins reduces the inflammation in the colon and other symptoms associated with ulcerative colitis.


The dosage and the drug form depend on the age, weight and medical condition of an individual. Use ROWASA PELLET as prescribed by your doctor.

  • Mix the required amount of ROWASA PELLET powder in a glass of cold water and drink it immediately.
  • Swallow the whole tablet. Do not crush or chew the tablet. Take the drug with or without food. However, taking the drug with food prevents stomach upset.
  • Use ROWASA PELLET enema as suggested by the doctor.

If you miss a dose of ROWASA PELLET, please use it immediately once you remember. However, if it is almost time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not use a double dose to make up for the missed dose.

The overdose symptoms of ROWASA PELLET may include:

  • Ringing in the ears
  • Confusion
  • Rapid breath
  • Seizures

What are the drugs that interact with ROWASA PELLET?

Drugs that interact with ROWASA PELLET include the following:

  • Cidofovir
  • Diatrizoate
  • Iodipamide
  • Iopamidol
  • Lopinavir
  • Tacrolimus

This is not a comprehensive list of drug interactions. Consult your doctor to know more about other possible drug interactions.

What are the side effects of ROWASA PELLET?

The following are the most common side effects of ROWASA PELLET:

  • Nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Itching
  • Dyspepsia

The following are the severe side effects, and you may require immediate medical attention:

  • Hair loss
  • Pancreatitis
  • Tremor
  • Gout
  • Shortness of breath
  • Chest pain

This is not a complete list of side effects and others may occur. Please consult your doctor to know more about other possible side effects.

What special precautions should be followed while using ROWASA PELLET?

  • Avoid using the medicine if you are allergic to ROWASA PELLET or similar drugs.
  • Avoid consumption of alcohol as it may alter the absorption of ROWASA PELLET.
  • Monitor your uric acid levels on a regular basis while using ROWASA PELLET.
  • Avoid ROWASA PELLET during pregnancy or breastfeeding because the safe use of the drug is not yet established.
  • Do not stop using the medication abruptly unless instructed by the doctor.
  • Do not exceed the dose more than prescribed.

What should you tell your doctor before using ROWASA PELLET?

  • Tell your doctor if you have any history of heart, liver, kidney or respiratory diseases.
  • Inform the doctor if you are taking any other drugs, OTC medications, herbal products or nutritional supplements.
  • Inform the doctor if you are pregnant or breastfeeding.

Frequently Asked questions about ROWASA PELLET

  1. Does ROWASA PELLET enema affect male fertility?
  2. Yes. ROWASA PELLET enema may alter the sperm count and affects the male fertility. Consult your doctor for further information.

  3. Can I use mesalamine tablet and enema at the same time?
  4. Yes. You can use ROWASA PELLET tablet and enema at the same time, only when recommended by the doctor.

  5. Is it safe to use ROWASA PELLET in anaemic patients?
  6. No. It is not safe to use ROWASA PELLET in patients with anaemia.

  7. Do I need to be monitored for any laboratory parameters while using ROWASA PELLET?
  8. Blood tests and Kidney function tests must be regularly monitored while using ROWASA PELLET.

  9. What are the other formulations of ROWASA PELLET available?
  10. ROWASA PELLET is available as granules, foam enemas, rectal suppositories, and capsules.



The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment.  Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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