INTRODUCTION

ROVAMYCIN FORTE contains Spiramycin which belongs to a group of medicines known as macrolide antibiotics. It is used to treat respiratory tract infections, prostatitis, urethritis, impetigo, folliculitis, toxoplasmosis in pregnant women and other conditions caused by bacteria. It works by inhibiting bacterial protein synthesis. Toxoplasmosis is a condition which causes miscarriage, stillbirth or damage to the baby's brain and other organs, particularly the eyes in pregnant women.

Spiramycin is a macrolide antibiotic, which reversibly binds to the bacterial ribosomes and inhibits the protein synthesis and subsequent cell growth. It is primarily bacteriostatic, but may be bactericidal against more sensitive strains when used in high concentrations. Spiramycin also accumulates in high concentrations in the bacterial cell. Unlike erythromycin, it does not produce gastrointestinal motility stimulation.

Always take this ROVAMYCIN FORTE exactly as directed by your doctor. Before taking this medicine, tell your doctor if you have liver, kidney or heart problems and if you have pregnant or breastfeeding. The common side effects are nausea, diarrhoea, gastric irritation and rashes.

USES OF ROVAMYCIN FORTE

• Treat bacterial infections

HOW ROVAMYCIN FORTE WORKS

ROVAMYCIN FORTE works by inhibiting bacterial protein synthesis and stops the bacteria from growing, and prevents the infection from spreading.

DIRECTIONS FOR USE

Always take this ROVAMYCIN FORTE exactly as your doctor has told you. Swallow as whole, do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF ROVAMYCIN FORTE

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to simple normal meals and do not eat rich or spicy foods.

Upset stomach:

Place a warm water bottle on your abdomen. Soak in a warm bath. Drink plenty of clear fluids and water.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

WARNING & PRECAUTIONS

INTERACTIONS

Inform your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following,

• erythromycin (used to treat infections)
• diuretics
• ergotamine, dihydroergotamine
• amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol (used to treat heart problems)

SYNOPSIS

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ROVAMYCIN FORTE

What is ROVAMYCIN FORTE used for?

It is used to treat bacterial infection by stopping the growth of bacteria.

What are the side effects of ROVAMYCIN FORTE?

The common side effects are nausea, vomiting, abdominal pain, diarrhea and allergic reactions. If this reaction persists, consult your doctor for advice.

Is ROVAMYCIN FORTE safe?

It is safe if used at prescribed doses for the prescribed duration as directed by the doctor.

REFERENCES

1. KD Tripathi MD. Anti-microbial drugs. Essentials of Medical Pharmacology 7th ed. New Delhi, May 2013. Page – 756.

2. Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. Page: 1421.

3. R. Sutherland. Spiramycin: a reappraisal of its antibacterial activity: British journal of pharmacology. Aug, 1962; [Accessed Jan 8, 2021] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482231/

USEFUL DIAGNOSTIC TESTS

• TORCH Profile IgG & IgM 10 Parameters
• Toxoplasma DNA PCR - Qualitative
• Toxoplasma gondii - IgG
• Toxoplasma gondii - IgM