INTRODUCTION

RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS contains Rizatriptan which belongs to the group of medicines called Selective serotonin 5-hydroxytryptamine receptor agonist. RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS is used in adults to treat headache phase of migraine attack.  

RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS is not recommended for use in patients allergic to Rizatriptan. It is also not recommended for use in patients suffering from moderate/mild/severe high blood pressure (which is not controlled by medication), stroke, peripheral vascular disease (condition marked by blockage of blood vessels), heart problems (such as heart attack, angina), and/or severe kidney/liver problems.

Before taking RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS, inform your doctor if you have diabetes, family history of heart disease, headache (associated with dizziness, difficulty in walking, lack of coordination), short lived symptoms (such as chest pain, tightness), and/or mild to moderate kidney/liver problems.

RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary as it is not known whether the medicine can cause harm to the unborn baby. It is also used with caution in breastfeeding women only if it is clearly necessary. Breastfeeding mothers should avoid nursing the child for next 24 hours after taking the medicine since it may cause unwanted effects in the nursing child.

RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS is not recommended for use in children and adolescents (aged below 18 years) and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor. 

The most common side effects of taking RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS are tingling sensation of hands/feet, headache, sleeplessness, dry mouth, nausea, vomiting, and/or diarrhea. Consult your doctor if any of these symptoms worsens.

USES OF RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS

• Treats headache experienced during migraine attack in adult patients

HOW RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS WORKS

RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS works by constricting the blood vessels that surround the brain which results in reduced swelling in the blood vessels thus providing relief from headache that occurs in migraine attack in affected individuals.

DIRECTIONS FOR USE

Tablet

Take RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Oral Disintegrating Tablet / Mouth Dissolving Tablet:

Take RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS as advised by your physician. Place RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS inside your mouth and allow it to dissolve completely. Do not swallow or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS

HOW TO MANAGE SIDE EFFECTS

Headache:

If RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS. If it lasts more than a week or severe, inform your doctor.

Dry mouth and thirst:

Try to drink plenty of cold water and sip on cold unsweetened drinks and use lip balm if your lips are dry. Brush your teeth twice a day and use mouthwash. Consult and inform your doctor if the symptom gets worse.

Nausea and vomiting:

Take RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS with or just after a meal. Stick to simple meals. Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking too much liquid along with your meals, drink slowly in between meals. Inform your doctor if the condition worsens.

Diarrhea:

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult and inform your doctor if the symptom worsens.

Indigestion:

Try to have smaller and more frequent meals and drink slowly. Reduce consumption of coffee, cola, tea, or alcohol and lose weight if you are obese.  Try to avoid smoking and don’t have rich, fatty or spicy foods. Consult your doctor and inform if the symptom does not improve.

Dizziness:

Try to rest and get enough sleep. Try to avoid driving or operating any tools or machines while you feel dizzy. Limit consumption of alcohol, as it can aggravate dizziness. Consult and inform your doctor if the symptom worsens.

Rashes:

Do not scratch the affected area. Wear protective clothing while going outdoors. Regularly moisturize your skin. Consult and inform your doctor if the symptom gets worse.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug Interactions

Before taking RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS, inform your doctor if you are taking any of the following medicine:

• other triptans (medicines used to treat migraine) Ex. ergotamine, dihydro-ergotamine, sumatriptan, naratriptan or zolmitriptan
• medicines used to treat depression such as selective serotonin reuptake inhibitors (SSRIs) (Ex.sertraline, escitalopram oxalate, uoxetine),  serotonin noradrenaline reuptake inhibitors (SNRIs) (Ex. venlafaxine, and duloxetine), monoamine oxidase (MAO) inhibitors (Ex. moclobemide, phenelzine, tranylcypromine, pargyline)
• medicines used to treat bacterial infections (Ex. linezolid)
• propranolol (used to treat heart problems, anxiety)
• methysergide (used to treat migraine)

Overdosage:

If you or anyone else accidentally takes too much of RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS, visit the nearby hospital or consult your doctor immediately. Symptoms of overdose are dizziness, drowsiness, vomiting, fainting, and/or slow heart rate.

SYNOPSIS

MORE INFORMATION

• Keep RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS out of sight and reach of children
• Do not store RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS above 30°C

FAQs ABOUT RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS

What is RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS and why it is used?

RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS contains Rizatriptan which belongs to the group of medicines called Selective serotonin 5-hydroxytryptamine receptor agonist. It is generally used to treat headache phase of migraine attack in adult patients.

What are the common side effects of RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS?

The most common side effects of taking RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS are tingling sensation of hands/feet, headache, sleeplessness, dry mouth, nausea, vomiting, and/or diarrhea. Consult your doctor if any of these symptoms worsens.

Can RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS be used in pregnant and breastfeeding women?

Yes, RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS can be used but with caution in pregnant and breastfeeding women only if necessary since it is not known whether the medicine can cause harm to the unborn baby/nursing child. Consult your doctor before taking the medicine.

How RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS works?

RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS works by constricting the blood vessels that surround the brain which results in reduced swelling in the blood vessels thus providing relief from headache that occurs in migraine attack in affected individuals.

What happens if RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS is taken more than its required dosage?

If you or anyone else accidentally takes too much of RIZORA O.D.S 5MG ORAL DISINTEGRATING STRIPS, visit the nearby hospital or consult your doctor immediately. Symptoms of overdose are dizziness, drowsiness, vomiting, fainting, and/or slow heart rate.

REFERENCES

1. KD. Tripathi. 5-Hydroxytryptamine, its Antagonists and Drug Therapy of Migraine. Essentials of medical pharmacology. Seventh edition. Page- 179.
2. Offie P. Soldin, Julia Dahlin, Daniel M. O’Mara. Triptans in Pregnancy. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. May 2013. [Accessed on 2nd December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644550/

3. MERCK SHARP & DOHME B.V. Electronic Medicines Compendium (EMC) [Revised in April 2022] [Accessed on 2nd December 2022] https://www.medicines.org.uk/emc/files/pil.7797.pdf

4. Intas Pharmaceuticals Ltd. Rizora- 5 & Rizora-10. [Accessed on 2nd December 2022] https://www.intaspharma.com/products/